Homo sapiens (human): 80201 Help Entry 80201             CDS       T01001                                  Symbol HKDC1, RP92 Name (RefSeq) hexokinase domain containing 1   KO K00844   hexokinase [EC:2.7.1.1] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa00051   Fructose and mannose metabolism hsa00052   Galactose metabolism hsa00500   Starch and sucrose metabolism hsa00520   Amino sugar and nucleotide sugar metabolism hsa00524   Neomycin, kanamycin and gentamicin biosynthesis hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa01250   Biosynthesis of nucleotide sugars hsa04066   HIF-1 signaling pathway hsa04910   Insulin signaling pathway hsa04930   Type II diabetes mellitus hsa04973   Carbohydrate digestion and absorption hsa05131   Shigellosis hsa05230   Central carbon metabolism in cancer Module hsa_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hsa_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Network nt06524  Apoptosis   Element N00950   Shigella FimA to crosstalk between extrinsic and intrinsic apoptotic pathways Disease H00527   Retinitis pigmentosa Drug target Lonidamine:  D07257 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     80201 (HKDC1)    00051 Fructose and mannose metabolism     80201 (HKDC1)    00052 Galactose metabolism     80201 (HKDC1)    00500 Starch and sucrose metabolism     80201 (HKDC1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     80201 (HKDC1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     80201 (HKDC1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     80201 (HKDC1)  09150 Organismal Systems   09154 Digestive system    04973 Carbohydrate digestion and absorption     80201 (HKDC1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     80201 (HKDC1)   09171 Infectious disease: bacterial    05131 Shigellosis     80201 (HKDC1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     80201 (HKDC1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     80201 (HKDC1) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      80201 (HKDC1) Membrane trafficking [BR:hsa04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     80201 (HKDC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  80201 NCBI-ProteinID:  NP_079406 OMIM:  617221 HGNC:  23302 Ensembl:  ENSG00000156510 UniProt:  Q2TB90 B3KT70 LinkDB All DBs Position 10:69220332..69267552 Genome browser AA seq 917 aa AA seqDB search MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI WTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA ALITAVAKRLQQAQKEN NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgtttgcggtccacttgatggcattttacttcagcaagctgaaggaggaccagatcaag aaggtggacaggttcctgtatcacatgcggctctccgatgacacccttttggacatcatg aggcggttccgggctgagatggagaagggcctggcaaaggacaccaaccccacggctgca gtgaagatgttgcccaccttcgtcagggccattcccgatggttccgaaaatggggagttc ctttccctggatctcggagggtccaagttccgagtgctgaaggtgcaagtcgctgaagag gggaagcgacacgtgcagatggagagtcagttctacccaacgcccaatgaaatcatccgc gggaacggcacagagctgtttgaatatgtagctgactgtctggcagatttcatgaagacc aaagatttaaagcataagaaattgccccttggcctaactttttctttcccctgtcgacag actaaactggaagagggtgtcctactttcgtggacaaaaaagtttaaggcacgaggagtt caggacacggatgtggtgagccgtctgaccaaagccatgagaagacacaaggacatggac gtggacatcctggccctggtcaatgacaccgtggggaccatgatgacctgtgcctatgac gacccctactgcgaagttggtgtcatcatcggaactggcaccaatgcgtgttacatggag gacatgagcaacattgacctggtggagggcgacgagggcaggatgtgcatcaacacagag tggggggccttcggggacgacggggccctggaggacattcgcactgagttcgacagggag ctggacctcggctctctcaacccaggaaagcaactgttcgagaagatgatcagtggcctg tacctgggggagcttgtcaggcttatcttgctgaagatggccaaggctggcctcctgttt ggtggtgagaaatcttctgctctccacactaagggcaagatcgaaacacggcacgtggct gccatggagaagtataaagaaggccttgctaatacaagagagatcctggtggacctgggt ctggaaccgtctgaggctgactgcattgccgtccagcatgtctgtaccatcgtctccttc cgctcggccaatctctgtgcagcagctctggcggccatcctgacacgcctccgggagaac aagaaggtggaacggctccggaccacagtgggcatggacggcaccctctacaagatacac cctcagtacccaaaacgcctgcacaaggtggtgaggaaactggtcccaagctgtgatgtc cgcttcctcctgtcagagagtggcagcaccaagggggccgccatggtgaccgcggtggcc tcccgcgtgcaggcccagcggaagcagatcgacagggtgctggctttgttccagctgacc cgagagcagctcgtggacgtgcaggccaagatgcgggctgagctggagtatgggctgaag aagaagagccacgggctggccacggtcaggatgctgcccacctacgtctgcgggctgccg gacggcacagagaaaggaaagtttctcgccctggatcttgggggaaccaacttccgggtc ctcctggtgaagatcagaagtggacggaggtcagtgcgaatgtacaacaagatcttcgcc atccccctggagatcatgcagggcactggtgaggagctctttgatcacattgtgcagtgc atcgccgacttcctggactacatgggcctcaagggagcctccctacctttgggcttcaca ttctcatttccctgcaggcagatgagcattgacaagggaacactcatagggtggaccaaa ggtttcaaggccactgactgtgaaggggaggacgtggtggacatgctcagggaagccatc aagaggagaaacgagtttgacctggacattgttgcagtcgtgaatgatacagtggggacc atgatgacctgtggctatgaagatcctaattgtgagattggcctgattgcaggaacaggc agcaacatgtgctacatggaggacatgaggaacatcgagatggtggaggggggtgaaggg aagatgtgcatcaatacagagtggggaggatttggagacaatggctgcatagatgacatc tggacccgatacgacacggaggtggatgaggggtccttgaatcctggcaagcagagatac gagaaaatgaccagtgggatgtacttgggggagattgtgcggcagatcctgatcgacctg accaagcagggtctcctcttccgagggcagatttcagagcgtctccggaccaggggcatc ttcgaaaccaagttcctgtcccagatcgaaagcgatcggctggcccttctccaggtcagg aggattctgcagcagctgggcctggacagcacgtgtgaggacagcatcgtggtgaaggag gtgtgcggagccgtgtcccggcgggcggcccagctctgcggtgctggcctggccgctata gtggaaaaaaggagagaagaccaggggctagagcacctgaggatcactgtgggtgtggac ggcaccctgtacaagctgcaccctcacttttctagaatattgcaggaaactgtgaaggaa ctagcccctcgatgtgatgtgacattcatgctgtcagaagatggcagtggaaaaggggca gcactgatcactgctgtggccaagaggttacagcaggcacagaaggagaactag

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