KEGG   Homo sapiens (human): 84868
Entry
84868             CDS       T01001                                 
Symbol
HAVCR2, CD366, HAVcr-2, KIM-3, SPTCL, TIM3, TIMD-3, TIMD3, Tim-3
Name
(RefSeq) hepatitis A virus cellular receptor 2
  KO
K20414  hepatitis A virus cellular receptor 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04148  Efferocytosis
Disease
H02661  Subcutaneous panniculitis-like T-cell lymphoma
Drug target
Cobolimab: D11377
Sabatolimab: D12164
Surzebiclimab: D12429
Verzistobart: D12798
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    84868 (HAVCR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    84868 (HAVCR2)
CD molecules [BR:hsa04090]
 Proteins
  84868 (HAVCR2)
SSDB
Motif
Pfam: V-set ig I-set Ig_3 Ig_2 Receptor_2B4
Other DBs
NCBI-GeneID: 84868
NCBI-ProteinID: NP_116171
OMIM: 606652
HGNC: 18437
Ensembl: ENSG00000135077
UniProt: Q8TDQ0
Structure
LinkDB
Position
5:complement(157085832..157109044)
AA seq 301 aa
MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPV
FECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMND
EKFNLKLVIKPAKVTPAPTRQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQISTLA
NELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHSKEKIQNLSLI
SLANLPPSGLANAVAEGIRSEENIYTIEENVYEVEEPNEYYCYVSSRQQPSQPLGCRFAM
P
NT seq 906 nt   +upstreamnt  +downstreamnt
atgttttcacatcttccctttgactgtgtcctgctgctgctgctgctactacttacaagg
tcctcagaagtggaatacagagcggaggtcggtcagaatgcctatctgccctgcttctac
accccagccgccccagggaacctcgtgcccgtctgctggggcaaaggagcctgtcctgtg
tttgaatgtggcaacgtggtgctcaggactgatgaaagggatgtgaattattggacatcc
agatactggctaaatggggatttccgcaaaggagatgtgtccctgaccatagagaatgtg
actctagcagacagtgggatctactgctgccggatccaaatcccaggcataatgaatgat
gaaaaatttaacctgaagttggtcatcaaaccagccaaggtcacccctgcaccgactcgg
cagagagacttcactgcagcctttccaaggatgcttaccaccaggggacatggcccagca
gagacacagacactggggagcctccctgatataaatctaacacaaatatccacattggcc
aatgagttacgggactctagattggccaatgacttacgggactctggagcaaccatcaga
ataggcatctacatcggagcagggatctgtgctgggctggctctggctcttatcttcggc
gctttaattttcaaatggtattctcatagcaaagagaagatacagaatttaagcctcatc
tctttggccaacctccctccctcaggattggcaaatgcagtagcagagggaattcgctca
gaagaaaacatctataccattgaagagaacgtatatgaagtggaggagcccaatgagtat
tattgctatgtcagcagcaggcagcaaccctcacaacctttgggttgtcgctttgcaatg
ccatag

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