Homo sapiens (human): 8877 Help Entry 8877              CDS       T01001                                  Symbol SPHK1, SPHK Name (RefSeq) sphingosine kinase 1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism hsa  Homo sapiens (human) Pathway hsa00600   Sphingolipid metabolism hsa01100   Metabolic pathways hsa04020   Calcium signaling pathway hsa04071   Sphingolipid signaling pathway hsa04072   Phospholipase D signaling pathway hsa04148   Efferocytosis hsa04370   VEGF signaling pathway hsa04371   Apelin signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa05152   Tuberculosis Module hsa_M00100   Sphingosine degradation Network nt06535  Efferocytosis   Element N01750   Find-me signal (S1P) Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     8877 (SPHK1)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     8877 (SPHK1)    04371 Apelin signaling pathway     8877 (SPHK1)    04020 Calcium signaling pathway     8877 (SPHK1)    04072 Phospholipase D signaling pathway     8877 (SPHK1)    04071 Sphingolipid signaling pathway     8877 (SPHK1)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     8877 (SPHK1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     8877 (SPHK1)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     8877 (SPHK1) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      8877 (SPHK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  8877 NCBI-ProteinID:  NP_001136073 OMIM:  603730 HGNC:  11240 Ensembl:  ENSG00000176170 UniProt:  Q9NYA1 Q53ZR5 Structure PDBPDBj LinkDB All DBs Position 17:76383204..76387855 Genome browser AA seq 384 aa AA seqDB search MDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHA RELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASL NHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLE SEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVP LEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLL RLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFW MVSGCVEPPPSWKPQQMPPPEEPL NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt atggatccagcgggcggcccccggggcgtgctcccgcggccctgccgcgtgctggtgctg ctgaacccgcgcggcggcaagggcaaggccttgcagctcttccggagtcacgtgcagccc cttttggctgaggctgaaatctccttcacgctgatgctcactgagcggcggaaccacgcg cgggagctggtgcggtcggaggagctgggccgctgggacgctctggtggtcatgtctgga gacgggctgatgcacgaggtggtgaacgggctcatggagcggcctgactgggagaccgcc atccagaagcccctgtgtagcctcccagcaggctctggcaacgcgctggcagcttccttg aaccattatgctggctatgagcaggtcaccaatgaagacctcctgaccaactgcacgcta ttgctgtgccgccggctgctgtcacccatgaacctgctgtctctgcacacggcttcgggg ctgcgcctcttctctgtgctcagcctggcctggggcttcattgctgatgtggacctagag agtgagaagtatcggcgtctgggggagatgcgcttcactctgggcaccttcctgcgtctg gcagccctgcgcacctaccgcggccgactggcctacctccctgtaggaagagtgggttcc aagacacctgcctcccccgttgtggtccagcagggcccggtagatgcacaccttgtgcca ctggaggagccagtgccctctcactggacagtggtgcccgacgaggactttgtgctagtc ctggcactgctgcactcgcacctgggcagtgagatgtttgctgcacccatgggccgctgt gcagctggcgtcatgcatctgttctacgtgcgggcgggagtgtctcgtgccatgctgctg cgcctcttcctggccatggagaagggcaggcatatggagtatgaatgcccctacttggta tatgtgcccgtggtcgccttccgcttggagcccaaggatgggaaaggtgtgtttgcagtg gatggggaattgatggttagcgaggccgtgcagggccaggtgcacccaaactacttctgg atggtcagcggttgcgtggagcccccgcccagctggaagccccagcagatgccaccgcca gaagagcccttatga

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