KEGG   Homo sapiens (human): 9217
Entry
9217              CDS       T01001                                 
Symbol
VAPB, ALS8, VAMP-B, VAP-B
Name
(RefSeq) VAMP associated protein B and C
  KO
K10707  vesicle-associated membrane protein-associated protein B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04979  Cholesterol metabolism
hsa05014  Amyotrophic lateral sclerosis
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06534  Unfolded protein response
  Element
N01150  Mutation-inactivated VAPB to ATF6-mediated transcription
Disease
H00058  Amyotrophic lateral sclerosis (ALS)
H00455  Spinal muscular atrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    9217 (VAPB)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    9217 (VAPB)
   05022 Pathways of neurodegeneration - multiple diseases
    9217 (VAPB)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9217 (VAPB)
Membrane trafficking [BR:hsa04131]
 Autophagy
  ER-phagy
   Other ER-phagy associated proteins
    9217 (VAPB)
  Other autophagy associated proteins
   ER-mitochondria tethering complex
    9217 (VAPB)
SSDB
Motif
Pfam: Motile_Sperm Ig_CFAP65_4th ZapB Cep192_D3 Cep192_D6 bZIP_1 LcrG Com_YlbF ATP-synt_G
Other DBs
NCBI-GeneID: 9217
NCBI-ProteinID: NP_004729
OMIM: 605704
HGNC: 12649
Ensembl: ENSG00000124164
UniProt: O95292 Q53XM7
Structure
LinkDB
Position
20:58389229..58451101
AA seq 243 aa
MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR
CVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEV
QRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGK
IAL
NT seq 732 nt   +upstreamnt  +downstreamnt
atggcgaaggtggagcaggtcctgagcctcgagccgcagcacgagctcaaattccgaggt
cccttcaccgatgttgtcaccaccaacctaaagcttggcaacccgacagaccgaaatgtg
tgttttaaggtgaagactacagcaccacgtaggtactgtgtgaggcccaacagcggaatc
atcgatgcaggggcctcaattaatgtatctgtgatgttacagcctttcgattatgatccc
aatgagaaaagtaaacacaagtttatggttcagtctatgtttgctccaactgacacttca
gatatggaagcagtatggaaggaggcaaaaccggaagaccttatggattcaaaacttaga
tgtgtgtttgaattgccagcagagaatgataaaccacatgatgtagaaataaataaaatt
atatccacaactgcatcaaagacagaaacaccaatagtgtctaagtctctgagttcttct
ttggatgacaccgaagttaagaaggttatggaagaatgtaagaggctgcaaggtgaagtt
cagaggctacgggaggagaacaagcagttcaaggaagaagatggactgcggatgaggaag
acagtgcagagcaacagccccatttcagcattagccccaactgggaaggaagaaggcctt
agcacccggctcttggctctggtggttttgttctttatcgttggtgtaattattgggaag
attgccttgtag

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