KEGG   Homo sapiens (human): 9474
Entry
9474              CDS       T01001                                 
Symbol
ATG5, APG5, APG5-LIKE, APG5L, ASP, SCAR25, hAPG5
Name
(RefSeq) autophagy related 5
  KO
K08339  autophagy-related protein 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04136  Autophagy - other
hsa04140  Autophagy - animal
hsa04211  Longevity regulating pathway
hsa04213  Longevity regulating pathway - multiple species
hsa04216  Ferroptosis
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa05131  Shigellosis
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06182  Shigella
nt06525  Ferroptosis
nt06532  Autophagy
  Element
N00156  Autophagy-vesicle nucleation/elongation/maturation, LC3-II formation
N01588  Fe3+ Ferritin transport
Disease
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    9474 (ATG5)
   04136 Autophagy - other
    9474 (ATG5)
  09143 Cell growth and death
   04216 Ferroptosis
    9474 (ATG5)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    9474 (ATG5)
   04622 RIG-I-like receptor signaling pathway
    9474 (ATG5)
  09149 Aging
   04211 Longevity regulating pathway
    9474 (ATG5)
   04213 Longevity regulating pathway - multiple species
    9474 (ATG5)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    9474 (ATG5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9474 (ATG5)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    9474 (ATG5)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Autophagosome formation proteins
   Atg12 conjugation proteins
    9474 (ATG5)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Autophagy-related proteins
    9474 (ATG5)
SSDB
Motif
Pfam: ATG5_UblA ATG5_UblB ATG5_HBR DUF6782
Other DBs
NCBI-GeneID: 9474
NCBI-ProteinID: NP_001273035
OMIM: 604261
HGNC: 589
Ensembl: ENSG00000057663
UniProt: Q9H1Y0 A9UGY9 Q7Z3H3
Structure
LinkDB
Position
6:complement(106184476..106325760)
AA seq 275 aa
MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVM
RQEDISEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDA
IEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEEN
GFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLKEVCPSAIDPEDGEKKNQVMI
HGIEPMLETPLQWLSEHLSYPDNFLHISIIPQPTD
NT seq 828 nt   +upstreamnt  +downstreamnt
atgacagatgacaaagatgtgcttcgagatgtgtggtttggacgaattccaacttgtttc
acgctatatcaggatgagataactgaaagggaagcagaaccatactatttgcttttgcca
agagtaagttatttgacgttggtaactgacaaagtgaaaaagcactttcagaaggttatg
agacaagaagacattagtgagatatggtttgaatatgaaggcacaccactgaaatggcat
tatccaattggtttgctatttgatcttcttgcatcaagttcagctcttccttggaacatc
acagtacattttaagagttttccagaaaaagaccttctgcactgtccatctaaggatgca
attgaagctcattttatgtcatgtatgaaagaagctgatgctttaaaacataaaagtcaa
gtaatcaatgaaatgcagaaaaaagatcacaagcaactctggatgggattgcaaaatgac
agatttgaccagttttgggccatcaatcggaaactcatggaatatcctgcagaagaaaat
ggatttcgttatatcccctttagaatatatcagacaacgactgaaagacctttcattcag
aagctgtttcgtcctgtggctgcagatggacagttgcacacactaggagatctcctcaaa
gaagtttgtccttctgctattgatcctgaagatggggaaaaaaagaatcaagtgatgatt
catggaattgagccaatgttggaaacacctctgcagtggctgagtgaacatctgagctac
ccggataattttcttcatattagtatcatcccacagccaacagattga

KEGG   Homo sapiens (human): 10533
Entry
10533             CDS       T01001                                 
Symbol
ATG7, APG7-LIKE, APG7L, GSA7, SCAR31
Name
(RefSeq) autophagy related 7
  KO
K08337  ubiquitin-like modifier-activating enzyme ATG7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04136  Autophagy - other
hsa04140  Autophagy - animal
hsa04216  Ferroptosis
hsa04613  Neutrophil extracellular trap formation
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06182  Shigella
nt06525  Ferroptosis
nt06532  Autophagy
  Element
N00156  Autophagy-vesicle nucleation/elongation/maturation, LC3-II formation
N01588  Fe3+ Ferritin transport
Disease
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    10533 (ATG7)
   04136 Autophagy - other
    10533 (ATG7)
  09143 Cell growth and death
   04216 Ferroptosis
    10533 (ATG7)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    10533 (ATG7)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10533 (ATG7)
   04121 Ubiquitin system [BR:hsa04121]
    10533 (ATG7)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    10533 (ATG7)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Autophagosome formation proteins
   Atg12 conjugation proteins
    10533 (ATG7)
   Atg8 conjugation proteins
    10533 (ATG7)
Ubiquitin system [BR:hsa04121]
 Ubiquitin-activating enzymes (E1)
  UBL-activating enzymes
   10533 (ATG7)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Autophagy-related proteins
    10533 (ATG7)
SSDB
Motif
Pfam: ATG7_N ThiF Shikimate_DH
Other DBs
NCBI-GeneID: 10533
NCBI-ProteinID: NP_006386
OMIM: 608760
HGNC: 16935
Ensembl: ENSG00000197548
UniProt: O95352 B3KQM6
LinkDB
Position
3:11272397..11576353
AA seq 703 aa
MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLP
ARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGT
ALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEAL
ECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQY
PGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPK
AVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLL
LGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADR
LQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRES
RWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLF
ANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEG
GYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYERE
GFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI
NT seq 2112 nt   +upstreamnt  +downstreamnt
atggcggcagctacgggggatcctggactctctaaactgcagtttgccccttttagtagt
gccttggatgttgggttttggcatgagttgacccagaagaagctgaacgagtatcggctg
gatgaagctcccaaggacattaagggttattactacaatggtgactctgctgggctgcca
gctcgcttaacattggagttcagtgcttttgacatgagtgctcccaccccagcccgttgc
tgcccagctattggaacactgtataacaccaacacactcgagtctttcaagactgcagat
aagaagctccttttggaacaagcagcaaatgagatatgggaatccataaaatcaggcact
gctcttgaaaaccctgtactcctcaacaagttcctcctcttgacatttgcagatctaaag
aagtaccacttctactattggttttgctatcctgccctctgtcttccagagagtttacct
ctcattcaggggccagtgggtttggatcaaaggttttcactaaaacagattgaagcacta
gagtgtgcatatgataatctttgtcaaacagaaggagtcacagctcttccttacttctta
atcaagtatgatgagaacatggtgctggtttccttgcttaaacactacagtgatttcttc
caaggtcaaaggacgaagataacaattggtgtatatgatccctgtaacttagcccagtac
cctggatggcctttgaggaattttttggtcctagcagcccacagatggagtagcagtttc
cagtctgttgaagttgtttgcttccgtgaccgtaccatgcagggggcgagagacgttgcc
cacagcatcatcttcgaagtgaagcttccagaaatggcatttagcccagattgtcctaaa
gcagttggatgggaaaagaaccagaaaggaggcatgggaccaaggatggtgaacctcagt
gaatgtatggaccctaaaaggttagctgagtcatcagtggatctaaatctcaaactgatg
tgttggagattggttcctactttagacttggacaaggttgtgtctgtcaaatgtctgctg
cttggagccggcaccttgggttgcaatgtagctaggacgttgatgggttggggcgtgaga
cacatcacatttgtggacaatgccaagatctcctactccaatcctgtgaggcagcctctc
tatgagtttgaagattgcctagggggtggtaagcccaaggctctggcagcagcggaccgg
ctccagaaaatattccccggtgtgaatgccagaggattcaacatgagcatacctatgcct
gggcatccagtgaacttctccagtgtcactctggagcaagcccgcagagatgtggagcaa
ctggagcagctcatcgaaagccatgatgtcgtcttcctattgatggacaccagggagagc
cggtggcttcctgccgtcattgctgcaagcaagagaaagctggtcatcaatgctgctttg
ggatttgacacatttgttgtcatgagacatggtctgaagaaaccaaagcagcaaggagct
ggggacttgtgtccaaaccaccctgtggcatctgctgacctcctgggctcatcgcttttt
gccaacatccctggttacaagcttggctgctacttctgcaatgatgtggtggccccagga
gattcaaccagagaccggaccttggaccagcagtgcactgtgagtcgtccaggactggcc
gtgattgcaggagccctggccgtggaattgatggtatctgttttgcagcatccagaaggg
ggctatgccattgccagcagcagtgacgatcggatgaatgagcctccaacctctcttggg
cttgtgcctcaccagatccggggatttctttcacggtttgataatgtccttcccgtcagc
ctggcatttgacaaatgtacagcttgttcttccaaagttcttgatcaatatgaacgagaa
ggatttaacttcctagccaaggtgtttaattcttcacattccttcttagaagacttgact
ggtcttacattgctgcatcaagaaacccaagctgctgagatctgggacatgagcgatgat
gagaccatctga

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