KEGG   Homo sapiens (human): 9861
Entry
9861              CDS       T01001                                 
Symbol
PSMD6, Rpn7, S10, SGA-113M, p42A, p44S10
Name
(RefSeq) proteasome 26S subunit, non-ATPase 6
  KO
K03037  26S proteasome regulatory subunit N7
Organism
hsa  Homo sapiens (human)
Pathway
hsa03050  Proteasome
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05017  Spinocerebellar ataxia
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05169  Epstein-Barr virus infection
Network
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
  Element
N01029  26S proteasome-mediated protein degradation
N01030  Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation
N01060  Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation
N01061  Mutation-caused aberrant Htt to 26S proteasome-mediated protein degradation
N01144  Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation
N01145  Mutation-inactivated VCP to 26S proteasome-mediated protein degradation
N01146  Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation
N01197  Scrapie conformation PrPSc to 26S proteasome-mediated protein degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03050 Proteasome
    9861 (PSMD6)
 09160 Human Diseases
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    9861 (PSMD6)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    9861 (PSMD6)
   05012 Parkinson disease
    9861 (PSMD6)
   05014 Amyotrophic lateral sclerosis
    9861 (PSMD6)
   05016 Huntington disease
    9861 (PSMD6)
   05017 Spinocerebellar ataxia
    9861 (PSMD6)
   05020 Prion disease
    9861 (PSMD6)
   05022 Pathways of neurodegeneration - multiple diseases
    9861 (PSMD6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03051 Proteasome [BR:hsa03051]
    9861 (PSMD6)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Regulatory particles
   PA700 (19S proteasome)
    non-ATPase subunits
     9861 (PSMD6)
SSDB
Motif
Pfam: RPN7 PCI RPN7_PSMD6_C
Other DBs
NCBI-GeneID: 9861
NCBI-ProteinID: NP_055629
OMIM: 617857
HGNC: 9564
Ensembl: ENSG00000163636
UniProt: Q15008
Structure
LinkDB
Position
3:complement(64010551..64024007)
AA seq 389 aa
MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKS
LDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGA
LTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRL
KVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKV
IKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMR
IHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPD
SKNWQYQETIKKGDLLLNRVQKLSRVINM
NT seq 1170 nt   +upstreamnt  +downstreamnt
atgccgctggagaacctggaggaggagggtctgcccaagaaccccgacttgcgtatcgcg
cagctgcgcttcctgctcagcctgcccgagcaccgcggagacgctgccgtgcgcgacgag
ctgatggcggccgtccgcgataacaacatggctccttactatgaagccttgtgcaaatcc
ctcgactggcagatagacgtggacctactcaataaaatgaagaaggcaaatgaagatgag
ttgaagcgtttggatgaggagctggaagatgcagagaagaatctaggagagagcgaaatt
cgcgatgcaatgatggcaaaggccgagtacctctgccggataggtgacaaagagggagct
ctgacagcctttcgcaagacatatgacaaaactgtggccctgggtcaccgattggatatt
gtattctatctccttaggattggcttattttatatggataatgatctcatcacacgaaac
acagaaaaggccaaaagcttaatagaagaaggaggagactgggacaggagaaaccgccta
aaagtgtatcagggtctttattgtgtggctattcgtgatttcaaacaggcagctgaactc
ttccttgacactgtttcaacatttacatcctatgaactcatggattataaaacatttgtg
acttatactgtctatgtcagtatgattgccttagaaagaccagatctcagggaaaaggtc
attaaaggagcagagattcttgaagtgttgcacagtcttccagcagttcggcagtatctg
ttttcactctatgaatgccgttactctgttttcttccaatcattagcggttgtggaacag
gaaatgaaaaaggactggctttttgcccctcattatcgatactatgtaagagaaatgaga
attcatgcatacagtcagctgctggaatcatataggtcattaacccttggctatatggca
gaagcgtttggtgttggtgtggaattcattgatcaggaactgtccaggtttattgctgcc
gggagactacactgcaaaatagataaagtgaatgaaatagtagaaaccaacagacctgat
agcaagaactggcagtaccaagaaactatcaagaaaggagatctgctactaaacagagtt
caaaaactttccagagtaattaatatgtaa

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