KEGG   Homo sapiens (human): 9965
Entry
9965              CDS       T01001                                 
Symbol
FGF19
Name
(RefSeq) fibroblast growth factor 19
  KO
K22603  fibroblast growth factor 19
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04810  Regulation of actin cytoskeleton
hsa05200  Pathways in cancer
hsa05218  Melanoma
hsa05224  Breast cancer
hsa05226  Gastric cancer
Network
nt06210  ERK signaling (cancer)
nt06214  PI3K signaling (cancer)
nt06261  Gastric cancer
nt06265  Bladder cancer
nt06270  Breast cancer
nt06526  MAPK signaling
nt06528  Calcium signaling
nt06530  PI3K signaling
  Element
N00019  FGF-FGFR-RAS-ERK signaling pathway
N00037  FGF-FGFR-PI3K signaling pathway
N01592  GF-RTK-RAS-ERK signaling pathway
N01641  RTK-PLCG-ITPR signaling pathway
N01656  GF-RTK-PI3K signaling pathway
N01658  GF-RTK-RAS-PI3K signaling pathway
Drug target
Aldafermin: D11734
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    9965 (FGF19)
   04014 Ras signaling pathway
    9965 (FGF19)
   04015 Rap1 signaling pathway
    9965 (FGF19)
   04020 Calcium signaling pathway
    9965 (FGF19)
   04151 PI3K-Akt signaling pathway
    9965 (FGF19)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    9965 (FGF19)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    9965 (FGF19)
  09162 Cancer: specific types
   05226 Gastric cancer
    9965 (FGF19)
   05218 Melanoma
    9965 (FGF19)
   05224 Breast cancer
    9965 (FGF19)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    9965 (FGF19)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    9965 (FGF19)
Cytokines and neuropeptides [BR:hsa04052]
 Cytokines
  Growth factors (RTK binding)
   9965 (FGF19)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   9965 (FGF19)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 9965
NCBI-ProteinID: NP_005108
OMIM: 603891
HGNC: 3675
Ensembl: ENSG00000162344
UniProt: O95750 A0A7U3L4E7
Structure
LinkDB
Position
11:complement(69698238..69704022)
AA seq 216 aa
MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFL
RIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDC
AFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLR
GHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
NT seq 651 nt   +upstreamnt  +downstreamnt
atgcggagcgggtgtgtggtggtccacgtatggatcctggccggcctctggctggccgtg
gccgggcgccccctcgccttctcggacgcggggccccacgtgcactacggctggggcgac
cccatccgcctgcggcacctgtacacctccggcccccacgggctctccagctgcttcctg
cgcatccgtgccgacggcgtcgtggactgcgcgcggggccagagcgcgcacagtttgctg
gagatcaaggcagtcgctctgcggaccgtggccatcaagggcgtgcacagcgtgcggtac
ctctgcatgggcgccgacggcaagatgcaggggctgcttcagtactcggaggaagactgt
gctttcgaggaggagatccgcccagatggctacaatgtgtaccgatccgagaagcaccgc
ctcccggtctccctgagcagtgccaaacagcggcagctgtacaagaacagaggctttctt
ccactctctcatttcctgcccatgctgcccatggtcccagaggagcctgaggacctcagg
ggccacttggaatctgacatgttctcttcgcccctggagaccgacagcatggacccattt
gggcttgtcaccggactggaggccgtgaggagtcccagctttgagaagtaa

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