Homo sapiens (human): 998
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Entry
998 CDS
T01001
Symbol
CDC42, CDC42Hs, G25K, TKS
Name
(RefSeq) cell division cycle 42
KO
K04393
cell division control protein 42
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04014
Ras signaling pathway
hsa04015
Rap1 signaling pathway
hsa04062
Chemokine signaling pathway
hsa04144
Endocytosis
hsa04360
Axon guidance
hsa04370
VEGF signaling pathway
hsa04510
Focal adhesion
hsa04520
Adherens junction
hsa04530
Tight junction
hsa04660
T cell receptor signaling pathway
hsa04666
Fc gamma R-mediated phagocytosis
hsa04670
Leukocyte transendothelial migration
hsa04722
Neurotrophin signaling pathway
hsa04810
Regulation of actin cytoskeleton
hsa04912
GnRH signaling pathway
hsa04932
Non-alcoholic fatty liver disease
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa05100
Bacterial invasion of epithelial cells
hsa05120
Epithelial cell signaling in Helicobacter pylori infection
hsa05130
Pathogenic Escherichia coli infection
hsa05131
Shigellosis
hsa05132
Salmonella infection
hsa05135
Yersinia infection
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05203
Viral carcinogenesis
hsa05205
Proteoglycans in cancer
hsa05211
Renal cell carcinoma
hsa05212
Pancreatic cancer
hsa05417
Lipid and atherosclerosis
Network
nt06180
Pathogenic Escherichia coli
nt06181
Salmonella
nt06182
Shigella
nt06521
NLR signaling
Element
N01070
ITGA/B-FAK-CDC42 signaling pathway
N01071
Shigella IpgB1 to ITGA/B-FAK-CDC42 signaling pathway
N01076
Shigella IcsB to ITGA/B-FAK-CDC42 signaling pathway
N01096
Escherichia Map to CDC42 signaling pathway
N01112
Salmonella SopE/E2 to NOD-NFKB signaling pathway
N01119
RAC/CDC42-PAK-ERK signaling pathway
N01120
Salmonella SptP to RAC/CDC42-PAK-ERK signaling pathway
N01134
Salmonella SopB to CDC42 signaling pathway
Disease
H02667
Takenouchi-Kosaki syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
998 (CDC42)
04014 Ras signaling pathway
998 (CDC42)
04015 Rap1 signaling pathway
998 (CDC42)
04370 VEGF signaling pathway
998 (CDC42)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
998 (CDC42)
09144 Cellular community - eukaryotes
04510 Focal adhesion
998 (CDC42)
04520 Adherens junction
998 (CDC42)
04530 Tight junction
998 (CDC42)
09142 Cell motility
04810 Regulation of actin cytoskeleton
998 (CDC42)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
998 (CDC42)
04666 Fc gamma R-mediated phagocytosis
998 (CDC42)
04670 Leukocyte transendothelial migration
998 (CDC42)
04062 Chemokine signaling pathway
998 (CDC42)
09152 Endocrine system
04912 GnRH signaling pathway
998 (CDC42)
09156 Nervous system
04722 Neurotrophin signaling pathway
998 (CDC42)
09158 Development and regeneration
04360 Axon guidance
998 (CDC42)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
998 (CDC42)
05205 Proteoglycans in cancer
998 (CDC42)
05203 Viral carcinogenesis
998 (CDC42)
09162 Cancer: specific types
05212 Pancreatic cancer
998 (CDC42)
05211 Renal cell carcinoma
998 (CDC42)
09172 Infectious disease: viral
05165 Human papillomavirus infection
998 (CDC42)
09171 Infectious disease: bacterial
05120 Epithelial cell signaling in Helicobacter pylori infection
998 (CDC42)
05130 Pathogenic Escherichia coli infection
998 (CDC42)
05132 Salmonella infection
998 (CDC42)
05131 Shigellosis
998 (CDC42)
05135 Yersinia infection
998 (CDC42)
05100 Bacterial invasion of epithelial cells
998 (CDC42)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
998 (CDC42)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
998 (CDC42)
04933 AGE-RAGE signaling pathway in diabetic complications
998 (CDC42)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
998 (CDC42)
03036 Chromosome and associated proteins [BR:
hsa03036
]
998 (CDC42)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
998 (CDC42)
04031 GTP-binding proteins [BR:
hsa04031
]
998 (CDC42)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Small GTPases and associated proteins
Rho GTPases
998 (CDC42)
Endocytosis
Lipid raft mediated endocytosis
GRAF1-dependent endocytosis
998 (CDC42)
Macropinocytosis
Ras GTPases
998 (CDC42)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
998 (CDC42)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of microglial cells
998 (CDC42)
Exosomal proteins of breast milk
998 (CDC42)
GTP-binding proteins [BR:
hsa04031
]
Small (monomeric) G-proteins
Rho Family
Rac/Cdc42 [OT]
998 (CDC42)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ras
Roc
Arf
GTP_EFTU
Motif
Other DBs
NCBI-GeneID:
998
NCBI-ProteinID:
NP_001034891
OMIM:
116952
HGNC:
1736
Ensembl:
ENSG00000070831
UniProt:
P60953
Structure
PDB
LinkDB
All DBs
Position
1:22052709..22101360
Genome browser
AA seq
191 aa
AA seq
DB search
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
EPKKSRRCVLL
NT seq
576 nt
NT seq
+upstream
nt +downstream
nt
atgcagacaattaagtgtgttgttgtgggcgatggtgctgttggtaaaacatgtctcctg
atatcctacacaacaaacaaatttccatcggaatatgtaccgactgtttttgacaactat
gcagtcacagttatgattggtggagaaccatatactcttggactttttgatactgcaggg
caagaggattatgacagattacgaccgctgagttatccacaaacagatgtatttctagtc
tgtttttcagtggtctctccatcttcatttgaaaacgtgaaagaaaagtgggtgcctgag
ataactcaccactgtccaaagactcctttcttgcttgttgggactcaaattgatctcaga
gatgacccctctactattgagaaacttgccaagaacaaacagaagcctatcactccagag
actgctgaaaagctggcccgtgacctgaaggctgtcaagtatgtggagtgttctgcactt
acacagaaaggcctaaagaatgtatttgacgaagcaatattggctgccctggagcctcca
gaaccgaagaagagccgcaggtgtgtgctgctatga
DBGET
integrated database retrieval system