Homo sapiens (human): 5265
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Entry
5265 CDS
T01001
Symbol
SERPINA1, A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT, nNIF
Name
(RefSeq) serpin family A member 1
KO
K03984
alpha-1-antitrypsin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04610
Complement and coagulation cascades
Network
nt06514
Coagulation cascade
Element
N01523
Regulation of fibrinolytic system, AAT
Disease
H01103
Alpha-1-antitrypsin deficiency
H01714
Chronic obstructive pulmonary disease (COPD)
Drug target
alfa1 Antitrypsin:
D11965
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
5265 (SERPINA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
5265 (SERPINA1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
5265 (SERPINA1)
Peptidases and inhibitors [BR:
hsa01002
]
Peptidase inhibitors
Family I4: serpin family
5265 (SERPINA1)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
5265 (SERPINA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Serpin
Motif
Other DBs
NCBI-GeneID:
5265
NCBI-ProteinID:
NP_000286
OMIM:
107400
HGNC:
8941
Ensembl:
ENSG00000197249
UniProt:
P01009
E9KL23
Structure
PDB
PDBj
LinkDB
All DBs
Position
14:complement(94376747..94390635)
Genome browser
AA seq
418 aa
AA seq
DB search
MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFS
LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGF
QELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQ
INDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTV
KVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFL
ENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKA
VLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQK
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
atgccgtcttctgtctcgtggggcatcctcctgctggcaggcctgtgctgcctggtccct
gtctccctggctgaggatccccagggagatgctgcccagaagacagatacatcccaccat
gatcaggatcacccaaccttcaacaagatcacccccaacctggctgagttcgccttcagc
ctataccgccagctggcacaccagtccaacagcaccaatatcttcttctccccagtgagc
atcgctacagcctttgcaatgctctccctggggaccaaggctgacactcacgatgaaatc
ctggagggcctgaatttcaacctcacggagattccggaggctcagatccatgaaggcttc
caggaactcctccgtaccctcaaccagccagacagccagctccagctgaccaccggcaat
ggcctgttcctcagcgagggcctgaagctagtggataagtttttggaggatgttaaaaag
ttgtaccactcagaagccttcactgtcaacttcggggacaccgaagaggccaagaaacag
atcaacgattacgtggagaagggtactcaagggaaaattgtggatttggtcaaggagctt
gacagagacacagtttttgctctggtgaattacatcttctttaaaggcaaatgggagaga
ccctttgaagtcaaggacaccgaggaagaggacttccacgtggaccaggtgaccaccgtg
aaggtgcctatgatgaagcgtttaggcatgtttaacatccagcactgtaagaagctgtcc
agctgggtgctgctgatgaaatacctgggcaatgccaccgccatcttcttcctgcctgat
gaggggaaactacagcacctggaaaatgaactcacccacgatatcatcaccaagttcctg
gaaaatgaagacagaaggtctgccagcttacatttacccaaactgtccattactggaacc
tatgatctgaagagcgtcctgggtcaactgggcatcactaaggtcttcagcaatggggct
gacctctccggggtcacagaggaggcacccctgaagctctccaaggccgtgcataaggct
gtgctgaccatcgacgagaaagggactgaagctgctggggccatgtttttagaggccata
cccatgtctatcccccccgaggtcaagttcaacaaaccctttgtcttcttaatgattgaa
caaaataccaagtctcccctcttcatgggaaaagtggtgaatcccacccaaaaataa
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