KEGG   PATHWAY: ko00514
Entry
ko00514                     Pathway                                
Name
Other types of O-glycan biosynthesis
Description
O-linked glycosylation is the attachment of monosaccharides to the hydroxyl groups of amino acids, mostly serine and threonine, and is found in eukaryotes, archaea and bacteria. O-glycans exhibit diverse types of modifications where the innermost monosaccharide is N-acetylgalactosamine (map00512), mannose in mammals (map00515), and others (this map) including N-acetylglucosamine, fucose, glucose, galactose, mannose in yeast and arabinose in plants.
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
ko00514  Other types of O-glycan biosynthesis
ko00514

Other DBs
GO: 0006493
Orthology
K00710  GALNT; polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]
K00728  POMT, pmt; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]
K00731  C1GALT1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122]
K00778  ST6GAL1; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.3.1]
K00779  ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.3.1]
K00781  ST3GAL3; N-acetyllactosaminide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.3.6]
K03691  POFUT; peptide-O-fucosyltransferase [EC:2.4.1.221]
K05538  MNN1; alpha 1,3-mannosyltransferase [EC:2.4.1.-]
K05948  FNG; fringe [EC:2.4.1.222]
K07966  B4GALT1; beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
K07967  B4GALT2; beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
K07968  B4GALT3; beta-1,4-galactosyltransferase 3 [EC:2.4.1.90 2.4.1.38 2.4.1.-]
K09653  C1GALT2, C1GALT1C1; C1GALT1-specific chaperone 1
K09667  OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
K10967  KTR1_3; alpha 1,2-mannosyltransferase [EC:2.4.1.-]
K10968  MNT2; alpha 1,3-mannosyltransferase [EC:2.4.1.-]
K10969  MNT3; alpha 1,3-mannosyltransferase [EC:2.4.1.-]
K10970  MNN25; alpha 1,2-mannosyltransferase [EC:2.4.1.-]
K10971  GMA12; alpha 1,2-galactosyltransferase [EC:2.4.1.-]
K11703  GLT25D; collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]
K13646  PLOD3; lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66]
K13667  POGLUT1, RUMI, KTELC1; EGF-domain serine glucosyl/xylosyltransferase [EC:2.4.1.376 2.4.2.63]
K13675  B3GALTL; UDP-glucose:O-linked fucose beta-1,3-glucosyltransferase [EC:2.4.1.-]
K13676  GXYLT; UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase [EC:2.4.2.42]
K18134  EOGT; EGF domain-specific O-GlcNAc transferase [EC:2.4.1.255]
K20781  SGT1; peptidyl serine alpha-galactosyltransferase [EC:2.4.1.-]
K20782  HPAT; hydroxyproline O-arabinosyltransferase [EC:2.4.2.58]
K20783  RRA; arabinosyltransferase [EC:2.4.2.-]
K20784  XEG113; arabinosyltransferase [EC:2.4.2.-]
K23800  XXYLT1; xylosyl alpha-1,3-xylosyltransferase
K23840  GlcAT-P; beta-1,3-glucuronyltransferase P
Reference
  Authors
Kizuka Y, Oka S
  Title
Regulated expression and neural functions of human natural killer-1 (HNK-1) carbohydrate.
  Journal
Cell Mol Life Sci 69:4135-47 (2012)
DOI:10.1007/s00018-012-1036-z
Reference
  Authors
Lommel M, Strahl S
  Title
Protein O-mannosylation: conserved from bacteria to humans.
  Journal
Glycobiology 19:816-28 (2009)
DOI:10.1093/glycob/cwp066

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