PATHWAY: ko00514 Help
Entry
Name
Other types of O-glycan biosynthesis
Description
O-linked glycosylation is the attachment of monosaccharides to the hydroxyl groups of amino acids, mostly serine and threonine, and is found in eukaryotes, archaea and bacteria. O-glycans exhibit diverse types of modifications where the innermost monosaccharide is N-acetylgalactosamine (
map00512 ), mannose in mammals (
map00515 ), and others (this map) including N-acetylglucosamine, fucose, glucose, galactose, mannose in yeast and arabinose in plants.
Class
Metabolism; Glycan biosynthesis and metabolism
BRITE hierarchy
Pathway map
ko00514 Other types of O-glycan biosynthesis
Other DBs
Orthology
K00710 GALNT; polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41 ]
K00728 POMT, pmt; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109 ]
K00731 C1GALT1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122 ]
K00778 ST6GAL1; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.3.1 ]
K00779 ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.3.1 ]
K00781 ST3GAL3; N-acetyllactosaminide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.3.6 ]
K05538 MNN1; alpha 1,3-mannosyltransferase [EC:2.4.1.-]
K09653 C1GALT2, C1GALT1C1; C1GALT1-specific chaperone 1
K10967 KTR1_3; alpha 1,2-mannosyltransferase [EC:2.4.1.-]
K10968 MNT2; alpha 1,3-mannosyltransferase [EC:2.4.1.-]
K10969 MNT3; alpha 1,3-mannosyltransferase [EC:2.4.1.-]
K10970 MNN25; alpha 1,2-mannosyltransferase [EC:2.4.1.-]
K10971 GMA12; alpha 1,2-galactosyltransferase [EC:2.4.1.-]
K13675 B3GALTL; UDP-glucose:O-linked fucose beta-1,3-glucosyltransferase [EC:2.4.1.-]
K13676 GXYLT; UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase [EC:2.4.2.42 ]
K20781 SGT1; peptidyl serine alpha-galactosyltransferase [EC:2.4.1.-]
K20783 RRA; arabinosyltransferase [EC:2.4.2.-]
K20784 XEG113; arabinosyltransferase [EC:2.4.2.-]
K23800 XXYLT1; xylosyl alpha-1,3-xylosyltransferase
K23840 GlcAT-P; beta-1,3-glucuronyltransferase P
Reference
Authors
Kizuka Y, Oka S
Title
Regulated expression and neural functions of human natural killer-1 (HNK-1) carbohydrate.
Journal
Reference
Authors
Lommel M, Strahl S
Title
Protein O-mannosylation: conserved from bacteria to humans.
Journal