| Entry |
|
| Symbol |
GSS
|
| Name |
|
| Pathway |
| map00270 | Cysteine and methionine metabolism |
|
| Module |
| M00118 | Glutathione biosynthesis, glutamate => glutathione |
|
| Reaction |
| R00497 | gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming) |
| R10994 | gamma-L-glutamyl-L-2-aminobutyrate:glycine ligase (ADP-forming) |
|
| Disease |
| H00668 | Anemia due to disorders of glutathione metabolism |
| H02312 | Glutathione synthetase deficiency |
| H02999 | Congenital nonspherocytic hemolytic anemia |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
K21456 GSS; glutathione synthase
09106 Metabolism of other amino acids
00480 Glutathione metabolism
K21456 GSS; glutathione synthase
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
K21456 GSS; glutathione synthase
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome
K21456 GSS; glutathione synthase
Enzymes [BR:ko01000]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.3 glutathione synthase
K21456 GSS; glutathione synthase
Exosome [BR:ko04147]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
K21456 GSS; glutathione synthase
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Gali RR, Board PG |
| Title |
Sequencing and expression of a cDNA for human glutathione synthetase. |
| Journal |
|
| Sequence |
|
| LinkDB |
|