KEGG   PATHWAY: mabb00975
Entry
mabb00975                   Pathway                                
Name
Biosynthesis of various siderophores - Mycobacteroides abscessus subsp. bolletii 50594
Class
Metabolism; Biosynthesis of other secondary metabolites
Pathway map
mabb00975  Biosynthesis of various siderophores
mabb00975

Organism
Mycobacteroides abscessus subsp. bolletii 50594 [GN:mabb]
Gene
MASS_1777  [KO:K00836] [EC:2.6.1.76]
MASS_1778  [KO:K13745] [EC:4.1.1.86]
MASS_2189  [KO:K00836] [EC:2.6.1.76]
Compound
C00025  L-Glutamate
C00047  L-Lysine
C00065  L-Serine
C00077  L-Ornithine
C00134  Putrescine
C00158  Citrate
C00230  3,4-Dihydroxybenzoate
C00315  Spermidine
C00441  L-Aspartate 4-semialdehyde
C00515  D-Ornithine
C00986  1,3-Diaminopropane
C01005  O-Phospho-L-serine
C01028  N6-Hydroxy-L-lysine
C01672  Cadaverine
C02637  3-Dehydroshikimate
C03283  L-2,4-Diaminobutanoate
C03401  L-2,3-Diaminopropanoate
C03955  N6-Acetyl-N6-hydroxy-L-lysine
C05554  Aerobactin
C06940  Deferoxamine
C20333  N2-Citryl-N6-acetyl-N6-hydroxy-L-lysine
C20883  3,4-Dihydroxybenzoyl-[aryl-carrier protein]
C20884  (3,4-Dihydroxybenzoyl)adenylate
C20885  N-Citryl-spermidine
C20952  N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine
C21559  N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate
C22004  N8,N'8-Citryl-bis(spermidine)
C22069  N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine)
C22072  2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate
C22073  2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate
C22074  2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate
C22075  Staphyloferrin B
C22101  N5-Citryl-D-ornithine
C22102  Staphyloferrin A
C22273  Petrobactin
C22888  N-Hydroxyputrescine
C22912  Pre-putrebactin
C22913  Putrebactin
C22914  N1-Hydroxy-N1-succinylputrescine
C22915  N1-Hydroxy-N1-succinylcadaverine
C22916  Bisucaberin B
C22917  Bisucaberin
C23083  O-Citrylserine
C23084  N-Citryl-ethanolamine
C23085  Diaminobutyryl-citryl-ethanolamine
C23086  alpha-Ketoglutaryl-diaminobutyryl-citryl-ethanolamine
C23087  Diaminobutyryl-citryl-ethanolamino-alpha-ketoglutarate
C23088  Achromobactin
C23089  Vibrioferrin
C23090  4-[[(3S)-4-Amino-3-hydroxybutyl]-hydroxyamino]-4-oxobutanoic acid
C23091  Alcaligin
C23092  N-Hydroxycadaverine
C23093  Desferrioxamine G1
C23094  Desferrioxamine E
C23095  N4-Hydroxy-1-aminopropane
C23096  N4-Acetyl-N4-hydroxy-1-aminopropane
C23097  N1-Citryl-N4-acetyl-N4-hydroxy-1-aminopropane
C23098  Schizokinen
C23099  Rhizobactin 1021
C23100  Alanyl-O-citryl-aminoehanol
C23101  N-Hydroxy-N-acetylcadaverine
C23102  Rhizoferrin
C23103  N-Citryputrescine
C23104  N-Citrylornithine
C23105  Pre-alcaligin
Reference
  Authors
Carroll CS, Moore MM
  Title
Ironing out siderophore biosynthesis: a review of non-ribosomal peptide synthetase (NRPS)-independent siderophore synthetases.
  Journal
Crit Rev Biochem Mol Biol 53:356-381 (2018)
DOI:10.1080/10409238.2018.1476449
Reference
PMID:1393837
  Authors
Neilands JB
  Title
Mechanism and regulation of synthesis of aerobactin in Escherichia coli K12 (pColV-K30).
  Journal
Can J Microbiol 38:728-33 (1992)
DOI:10.1139/m92-119
Reference
  Authors
Ronan JL, Kadi N, McMahon SA, Naismith JH, Alkhalaf LM, Challis GL.
  Title
Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant  acyl transferase DesC.
  Journal
Philos Trans R Soc Lond B Biol Sci 373 (2018)
DOI:10.1098/rstb.2017.0068
Reference
  Authors
Lynch D, O'Brien J, Welch T, Clarke P, Cuiv PO, Crosa JH, O'Connell M.
  Title
Genetic organization of the region encoding regulation, biosynthesis, and  transport of rhizobactin 1021, a siderophore produced by Sinorhizobium meliloti.
  Journal
J Bacteriol 183:2576-85 (2001)
Reference
  Authors
Challis GL.
  Title
A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases.
  Journal
Chembiochem 6:601-11 (2005)
DOI:10.1002/cbic.200400283
Reference
  Authors
Cotton JL, Tao J, Balibar CJ
  Title
Identification and characterization of the Staphylococcus aureus gene cluster coding for staphyloferrin A.
  Journal
Biochemistry 48:1025-35 (2009)
DOI:10.1021/bi801844c
Reference
  Authors
Li B, Deng X, Kim SH, Buhrow L, Tomchick DR, Phillips MA, Michael AJ.
  Title
Alternative pathways utilize or circumvent putrescine for biosynthesis of  putrescine-containing rhizoferrin.
  Journal
J Biol Chem 296:100146 (2021)
DOI:10.1074/jbc.RA120.016738
Reference
  Authors
Cheung J, Beasley FC, Liu S, Lajoie GA, Heinrichs DE
  Title
Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus.
  Journal
Mol Microbiol 74:594-608 (2009)
DOI:10.1111/j.1365-2958.2009.06880.x
Reference
  Authors
Tanabe T, Mitome H, Miyamoto K, Akira K, Tsujibo H, Tomoo K, Nagaoka K, Funahashi T.
  Title
Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus.
  Journal
Biometals 37:507-517 (2024)
DOI:10.1007/s10534-023-00566-x
Reference
  Authors
Tanabe T, Funahashi T, Nakao H, Miyoshi S, Shinoda S, Yamamoto S
  Title
Identification and characterization of genes required for biosynthesis and transport of the siderophore vibrioferrin in Vibrio parahaemolyticus.
  Journal
J Bacteriol 185:6938-49 (2003)
DOI:10.1128/JB.185.23.6938-6949.2003
KO pathway
ko00975   

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