KEGG   PATHWAY: mah00740
Entry
mah00740                    Pathway                                
Name
Riboflavin metabolism - Methylotuvimicrobium alcaliphilum
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
mah00740  Riboflavin metabolism
mah00740

Other DBs
GO: 0006771
Organism
Methylotuvimicrobium alcaliphilum [GN:mah]
Gene
MEALZ_3560  GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
MEALZ_0717  Riboflavin-specific deaminase/GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
MEALZ_2917  ribAB; Riboflavin biosynthesis protein ribAB [Includes: GTP cyclohydrolase-2 (GTP cyclohydrolase II); 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase)] [KO:K14652] [EC:4.1.99.12 3.5.4.25]
MEALZ_2919  ribD; bifunctional riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (HTP reductase)] [KO:K11752] [EC:3.5.4.26 1.1.1.193]
MEALZ_2916  ribH; 6,7-dimethyl-8-ribityllumazine synthase (Lumazine synthase)(riboflavin synthase beta chain) [KO:K00794] [EC:2.5.1.78]
MEALZ_2918  ribC; riboflavin synthase alpha chain [KO:K00793] [EC:2.5.1.9]
MEALZ_3584  ribF; bifunctional riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)] [KO:K11753] [EC:2.7.1.26 2.7.7.2]
MEALZ_0954  bluB; putative 5,6-dimethylbenzimidazole synthase (flavin destructase), putative cob(II)yrinic acid a, c-diamide reductase [KO:K04719] [EC:1.13.11.79]
MEALZ_1895  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
MEALZ_0591  ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase (Polyprenyl p-hydroxybenzoate decarboxylase) [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
PMID:12136096
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
PMID:11856310
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
PMID:12867427
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
PMID:16042598
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
mah00030  Pentose phosphate pathway
mah00040  Pentose and glucuronate interconversions
mah00230  Purine metabolism
mah00860  Porphyrin metabolism
mah00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

DBGET integrated database retrieval system