KEGG   MODULE: nmg_M00740
Entry
nmg_M00740        Pathway   Module                                 
Name
Methylaspartate cycle
Definition
(K01647,K01659) K27802 K00031 K00261 K19268+K01846 K04835 K19280 K14449 K19281 K19282 K00024
Diagram
nmg_M00740  Methylaspartate cycle
nmg_M00740

Class
Pathway modules; Carbohydrate metabolism; Other carbohydrate metabolism
Pathway
nmg00020  Citrate cycle (TCA cycle)
nmg00250  Alanine, aspartate and glutamate metabolism
nmg00630  Glyoxylate and dicarboxylate metabolism
nmg01200  Carbon metabolism
nmg01100  Metabolic pathways
nmg01120  Microbial metabolism in diverse environments
Organism
Natrialba magadii [GN:nmg]
Gene
Nmag_1476  citZ1; citrate synthase [KO:K01659]
Nmag_1974  mdh; malate dehydrogenase [KO:K00024]
Nmag_2322  gdhA3; glutamate dehydrogenase (NAD) [KO:K00261]
Nmag_2325  gdhA2; glutamate dehydrogenase (NADP) [KO:K00261]
Nmag_2420  citZ3; citrate synthase [KO:K01647]
Nmag_2423  citZ2; citrate synthase [KO:K01647]
Nmag_2939  icd; isocitrate dehydrogenase (NADP) [KO:K00031]
Nmag_2989  citB2; aconitate hydratase [KO:K27802]
Nmag_3333  mct; succinyl-CoA:mesaconate CoA-transferase [KO:K19280]
Nmag_3334  mamA; methylaspartate mutase small subunit [KO:K01846]
Nmag_3335  mamB; methylaspartate mutase large subunit [KO:K19268]
Nmag_3336  mal; methylaspartate ammonia-lyase [KO:K04835]
Nmag_3337  msh; mesaconyl-CoA hydratase [KO:K14449]
Nmag_3338  mcl; beta-methylmalyl-CoA lyase [KO:K19281]
Nmag_3363  aceB; malate synthase [KO:K19282]
Nmag_3671  gdhA1; glutamate dehydrogenase (NAD) [KO:K00261]
Nmag_3761  gdhA4; glutamate dehydrogenase (NAD) [KO:K00261]
Reaction
R00351  
R01325  
R01900  
R01899  
R00268  
R00248  
R00262  
R03696  
R10904  
R05076  
R00934  
R00473  
R10612  
R00342  
Compound
C00036  Oxaloacetate
C00024  Acetyl-CoA
C00158  Citrate
C00417  cis-Aconitate
C00311  Isocitrate
C05379  Oxalosuccinate
C00026  2-Oxoglutarate
C00025  L-Glutamate
C03618  L-threo-3-Methylaspartate
C01732  Mesaconate
C06028  2-Methylfumaryl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C00048  Glyoxylate
C04348  L-Malyl-CoA
C00149  (S)-Malate
Comment
Acetyl-CoA assimilation via the methylaspartate cycle: M00740+M00741
Organism group: haloarchaea (halobacteria)
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
KO module
M00740
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