| Entry |
|
| Symbol |
prpC
|
| Name |
2-methylcitrate synthase [EC: 2.3.3.5]
|
| Pathway |
| map00630 | Glyoxylate and dicarboxylate metabolism |
| map01110 | Biosynthesis of secondary metabolites |
| map01120 | Microbial metabolism in diverse environments |
| map01210 | 2-Oxocarboxylic acid metabolism |
|
| Module |
| M00009 | Citrate cycle (TCA cycle, Krebs cycle) |
| M00010 | Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate |
|
| Reaction |
| R00351 | acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing) |
| R00931 | propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming) |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K01659 prpC; 2-methylcitrate synthase
00630 Glyoxylate and dicarboxylate metabolism
K01659 prpC; 2-methylcitrate synthase
00640 Propanoate metabolism
K01659 prpC; 2-methylcitrate synthase
Enzymes [BR:ko01000]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.5 2-methylcitrate synthase
K01659 prpC; 2-methylcitrate synthase
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Gerike U, Hough DW, Russell NJ, Dyall-Smith ML, Danson MJ |
| Title |
Citrate synthase and 2-methylcitrate synthase: structural, functional and evolutionary relationships. |
| Journal |
|
| Reference |
|
| Authors |
Horswill AR, Escalante-Semerena JC |
| Title |
Salmonella typhimurium LT2 catabolizes propionate via the 2-methylcitric acid cycle. |
| Journal |
|
| Sequence |
|
| Reference |
|
| Authors |
Munoz-Elias EJ, Upton AM, Cherian J, McKinney JD |
| Title |
Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence. |
| Journal |
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| Sequence |
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| LinkDB |
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