EGF-EGFR-RAS-ERK signaling pathway

Amplified EGFR to RAS-ERK signaling pathway

EGFR-overexpression to RAS-ERK signaling pathway

EGF-ERBB2-RAS-ERK signaling pathway

ERBB2-overexpression to RAS-ERK signaling pathway

FGF-FGFR-RAS-ERK signaling pathway

Mutation-activated FGFR3 to RAS-ERK signaling pathway

HRAS-overexpression to ERK signaling pathway

Mutation-activated HRAS to ERK signaling pathway

MDM2-p21-Cell cycle G1/S

Deleted p14(ARF) to p21-cell cycle G1/S

p16-Cell cycle G1/S

Deleted p16(INK4a) to p16-cell cycle G1/S

Loss of RB1 to cell cycle G1/S

Mutation-inactivated RB1 to cell cycle G1/S

Mutation-inactivated TP53 to transcription