Ochotona princeps (American pika): 101531640 Help Entry 101531640         CDS       T07609                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X1   KO K02187   caspase 3 [EC:3.4.22.56] Organism opi  Ochotona princeps (American pika) Pathway opi01524   Platinum drug resistance opi04010   MAPK signaling pathway opi04115   p53 signaling pathway opi04148   Efferocytosis opi04210   Apoptosis opi04215   Apoptosis - multiple species opi04623   Cytosolic DNA-sensing pathway opi04650   Natural killer cell mediated cytotoxicity opi04657   IL-17 signaling pathway opi04668   TNF signaling pathway opi04726   Serotonergic synapse opi04932   Non-alcoholic fatty liver disease opi04933   AGE-RAGE signaling pathway in diabetic complications opi04936   Alcoholic liver disease opi05010   Alzheimer disease opi05012   Parkinson disease opi05014   Amyotrophic lateral sclerosis opi05016   Huntington disease opi05020   Prion disease opi05022   Pathways of neurodegeneration - multiple diseases opi05132   Salmonella infection opi05133   Pertussis opi05134   Legionellosis opi05145   Toxoplasmosis opi05146   Amoebiasis opi05152   Tuberculosis opi05160   Hepatitis C opi05161   Hepatitis B opi05162   Measles opi05163   Human cytomegalovirus infection opi05164   Influenza A opi05165   Human papillomavirus infection opi05167   Kaposi sarcoma-associated herpesvirus infection opi05168   Herpes simplex virus 1 infection opi05169   Epstein-Barr virus infection opi05170   Human immunodeficiency virus 1 infection opi05200   Pathways in cancer opi05203   Viral carcinogenesis opi05205   Proteoglycans in cancer opi05206   MicroRNAs in cancer opi05210   Colorectal cancer opi05222   Small cell lung cancer opi05416   Viral myocarditis opi05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:opi00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101531640 (CASP3)    04668 TNF signaling pathway     101531640 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     101531640 (CASP3)   09143 Cell growth and death    04210 Apoptosis     101531640 (CASP3)    04215 Apoptosis - multiple species     101531640 (CASP3)    04115 p53 signaling pathway     101531640 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     101531640 (CASP3)    04650 Natural killer cell mediated cytotoxicity     101531640 (CASP3)    04657 IL-17 signaling pathway     101531640 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     101531640 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101531640 (CASP3)    05206 MicroRNAs in cancer     101531640 (CASP3)    05205 Proteoglycans in cancer     101531640 (CASP3)    05203 Viral carcinogenesis     101531640 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     101531640 (CASP3)    05222 Small cell lung cancer     101531640 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101531640 (CASP3)    05161 Hepatitis B     101531640 (CASP3)    05160 Hepatitis C     101531640 (CASP3)    05164 Influenza A     101531640 (CASP3)    05162 Measles     101531640 (CASP3)    05168 Herpes simplex virus 1 infection     101531640 (CASP3)    05163 Human cytomegalovirus infection     101531640 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     101531640 (CASP3)    05169 Epstein-Barr virus infection     101531640 (CASP3)    05165 Human papillomavirus infection     101531640 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     101531640 (CASP3)    05133 Pertussis     101531640 (CASP3)    05134 Legionellosis     101531640 (CASP3)    05152 Tuberculosis     101531640 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     101531640 (CASP3)    05145 Toxoplasmosis     101531640 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     101531640 (CASP3)    05012 Parkinson disease     101531640 (CASP3)    05014 Amyotrophic lateral sclerosis     101531640 (CASP3)    05016 Huntington disease     101531640 (CASP3)    05020 Prion disease     101531640 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     101531640 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101531640 (CASP3)    05416 Viral myocarditis     101531640 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101531640 (CASP3)    04932 Non-alcoholic fatty liver disease     101531640 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     101531640 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101531640 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:opi01002]     101531640 (CASP3) Enzymes [BR:opi01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      101531640 (CASP3) Peptidases and inhibitors [BR:opi01002]  Cysteine peptidases   Family C14: caspase family    101531640 (CASP3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  101531640 NCBI-ProteinID:  XP_004579072 LinkDB All DBs Position 2A:complement(50477506..50495037) Genome browser AA seq 277 aa AA seqDB search MENAEISVDSKSIKNSETKILQGSKSVNSGISLERSYKMDYPEMGLCIIINNKNFHTSTG MAPRSGTDVDAAKLRETFMNLKYDVKNKNDLTCEEIVELLRNVSKEDHSKRSSFICVILS HGEEGRIFGTNGSIELKKLTNLFRGDCCRSLTGKPKLFIIQACRGTELDSGIETDSAVEN DTVCQKIPVEADFLYAYSTAPGYYSWRNSKEGSWFIQSLCEMLKEYAHKLEFMHILTRVN WKVATEFESYSLDANFHAKKQVPCIVSMLTKELYFYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacgctgaaatctctgtggattcaaaatccattaaaaattcggaaacaaagatc ctccagggaagcaaatcagtgaactcaggaatatctctggagagaagttacaaaatggat tatcctgaaatgggcttatgcataatcattaataacaagaacttccatacaagcactgga atggcgcctcgatctggtacagatgttgatgcagcaaaactcagggaaacattcatgaac ttgaaatatgatgtcaaaaataaaaatgatcttacatgtgaagaaattgtggaactcctg cgcaatgtttctaaagaagatcacagcaaaaggagcagttttatttgtgtgattttaagc cacggcgaggaaggacgcatttttggaacaaatgggtctattgaactgaaaaaactaaca aatttgttcagaggggattgttgtagaagtctaactggaaagcctaaacttttcattatt caggcctgccgaggcacagagctggacagcggtatcgaaacagacagtgcggtcgaaaat gacacagtgtgccagaaaataccagttgaagctgacttcttatatgcatattctacagcg cctggttactattcctggcgaaattcaaaggaagggtcctggttcatccagtcactctgt gagatgctgaaggaatacgctcacaagctggagttcatgcacatccttacccgggtgaac tggaaggtagccacagaatttgagtcctactccctcgatgccaattttcatgcgaagaaa caggttccatgtattgtgtccatgctcacaaaagagctgtatttttatcactga

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