KEGG   PATHWAY: apes00061
Entry
apes00061                   Pathway                                
Name
Fatty acid biosynthesis - Achromobacter pestifer
Class
Metabolism; Lipid metabolism
Pathway map
apes00061  Fatty acid biosynthesis
apes00061

Module
apes_M00082  Fatty acid biosynthesis, initiation [PATH:apes00061]
apes_M00083  Fatty acid biosynthesis, elongation [PATH:apes00061]
apes_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:apes00061]
Other DBs
GO: 0006633
Organism
Achromobacter pestifer [GN:apes]
Gene
FOC84_23130  acetyl-CoA carboxylase carboxyltransferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
FOC84_09400  acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
FOC84_21425  biotin carboxyl carrier domain-containing protein [KO:K02160]
FOC84_09395  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
FOC84_21420  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
FOC84_01930  ATP-grasp domain-containing protein [KO:K01961] [EC:6.4.1.2 6.3.4.14]
FOC84_05125  biotin carboxylase [KO:K01961] [EC:6.4.1.2 6.3.4.14]
FOC84_04945  acetyl-CoA carboxylase carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
FOC84_04855  fabD; ACP S-malonyltransferase [KO:K00645] [EC:2.3.1.39]
FOC84_13625  iron-containing redox enzyme family protein [KO:K00648] [EC:2.3.1.180]
FOC84_04860  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
FOC84_01155  beta-ketoacyl-ACP synthase [KO:K00647] [EC:2.3.1.41]
FOC84_24590  fabF; beta-ketoacyl-ACP synthase II [KO:K09458] [EC:2.3.1.179]
FOC84_01170  beta-ketoacyl-ACP synthase [KO:K09458] [EC:2.3.1.179]
FOC84_04840  fabF; beta-ketoacyl-ACP synthase II [KO:K09458] [EC:2.3.1.179]
FOC84_08345  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_09740  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_09820  3-oxoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
FOC84_09910  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_16425  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_18485  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_21590  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_22000  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_26565  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_28270  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_30710  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_32730  3-oxoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
FOC84_33280  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_01165  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
FOC84_04095  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
FOC84_04850  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
FOC84_06275  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
FOC84_08130  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_19440  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_24975  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_15695  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
FOC84_31730  fabZ; 3-hydroxyacyl-ACP dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
FOC84_08935  fabI; enoyl-ACP reductase FabI [KO:K00208] [EC:1.3.1.9 1.3.1.10]
FOC84_20420  fabI; enoyl-ACP reductase FabI [KO:K00208] [EC:1.3.1.9 1.3.1.10]
FOC84_28465  trans-2-enoyl-CoA reductase family protein [KO:K00209] [EC:1.3.1.9 1.3.1.44]
FOC84_14265  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_21330  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_23340  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_23700  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_25860  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
FOC84_26070  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_26970  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_32840  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_32945  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_04075  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_05835  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
FOC84_07915  acyl--CoA ligase [KO:K01897] [EC:6.2.1.3]
FOC84_08300  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
PMID:12061798
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
PMID:12518017
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
PMID:11337402
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
PMID:17573542
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
PMID:30201289
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
PMID:25203508
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
PMID:19686777
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
PMID:27553474
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
apes00020  Citrate cycle (TCA cycle)
apes00071  Fatty acid degradation
apes00410  beta-Alanine metabolism
apes00561  Glycerolipid metabolism
apes00564  Glycerophospholipid metabolism
apes00620  Pyruvate metabolism
apes00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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