KEGG   PATHWAY: aroo02010
Entry
aroo02010                   Pathway                                
Name
ABC transporters - Amycolatopsis roodepoortensis
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
aroo02010  ABC transporters
aroo02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Amycolatopsis roodepoortensis [GN:aroo]
Gene
NQK81_14865  ABC transporter substrate-binding protein [KO:K15553]
NQK81_14855  ABC transporter permease [KO:K15554]
NQK81_14860  ABC transporter ATP-binding protein [KO:K15555] [EC:7.6.2.14]
NQK81_29110  modA; molybdate ABC transporter substrate-binding protein [KO:K02020]
NQK81_29115  ABC transporter permease [KO:K02018]
NQK81_29120  ATP-binding cassette domain-containing protein [KO:K02017] [EC:7.3.2.5]
NQK81_31740  thiamine ABC transporter substrate-binding protein [KO:K02064]
NQK81_31745  iron ABC transporter permease [KO:K02063]
NQK81_31750  ABC transporter ATP-binding protein [KO:K02062] [EC:7.6.2.15]
NQK81_09635  2-aminoethylphosphonate ABC transporter substrate-binding protein [KO:K11081]
NQK81_09620  ABC transporter permease subunit [KO:K11082]
NQK81_09625  2-aminoethylphosphonate ABC transporter permease subunit [KO:K11083]
NQK81_09630  ABC transporter ATP-binding protein [KO:K11084]
NQK81_20575  ABC transporter substrate-binding protein [KO:K05845]
NQK81_26115  glycine betaine ABC transporter substrate-binding protein [KO:K05845]
NQK81_32170  ABC transporter substrate-binding protein [KO:K05845]
NQK81_43400  glycine betaine ABC transporter substrate-binding protein [KO:K05845]
NQK81_20580  ABC transporter permease [KO:K05846]
NQK81_20585  ABC transporter permease subunit [KO:K05846]
NQK81_26100  ABC transporter permease [KO:K05846]
NQK81_26110  ABC transporter permease [KO:K05846]
NQK81_32160  ABC transporter permease [KO:K05846]
NQK81_32165  ABC transporter permease subunit [KO:K05846]
NQK81_43395  ABC transporter permease [KO:K05846]
NQK81_26105  ABC transporter ATP-binding protein [KO:K05847] [EC:7.6.2.9]
NQK81_32155  ATP-binding cassette domain-containing protein [KO:K05847] [EC:7.6.2.9]
NQK81_17535  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10112] [EC:7.5.2.-]
NQK81_19190  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10112] [EC:7.5.2.-]
NQK81_40910  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10112] [EC:7.5.2.-]
NQK81_04220  extracellular solute-binding protein [KO:K10117]
NQK81_39360  extracellular solute-binding protein [KO:K10117]
NQK81_39355  sugar ABC transporter permease [KO:K10118]
NQK81_40905  carbohydrate ABC transporter permease [KO:K10119]
NQK81_04230  carbohydrate ABC transporter permease [KO:K10119]
NQK81_39350  carbohydrate ABC transporter permease [KO:K10119]
NQK81_18510  sugar ABC transporter substrate-binding protein [KO:K10227]
NQK81_18505  sugar ABC transporter permease [KO:K10228]
NQK81_18500  carbohydrate ABC transporter permease [KO:K10229]
NQK81_41020  ABC transporter substrate-binding protein [KO:K10232]
NQK81_17550  ABC transporter substrate-binding protein [KO:K10236]
NQK81_17545  sugar ABC transporter permease [KO:K10237]
NQK81_17540  carbohydrate ABC transporter permease [KO:K10238]
NQK81_40505  ABC transporter substrate-binding protein [KO:K10240]
NQK81_44520  extracellular solute-binding protein [KO:K10240]
NQK81_40480  sugar ABC transporter permease [KO:K10241]
NQK81_44515  sugar ABC transporter permease [KO:K10241]
NQK81_40485  carbohydrate ABC transporter permease [KO:K10242]
NQK81_44510  carbohydrate ABC transporter permease [KO:K10242]
NQK81_16205  extracellular solute-binding protein [KO:K17329]
NQK81_41440  extracellular solute-binding protein [KO:K17329]
NQK81_16210  sugar ABC transporter permease [KO:K17330]
NQK81_41435  sugar ABC transporter permease [KO:K17330]
NQK81_16215  carbohydrate ABC transporter permease [KO:K17331]
NQK81_41430  carbohydrate ABC transporter permease [KO:K17331]
NQK81_44570  chvE; sugar ABC transporter substrate-binding protein [KO:K10546]
NQK81_44580  gguB; sugar ABC transporter permease [KO:K10547]
NQK81_44575  gguA; sugar ABC transporter ATP-binding protein [KO:K10548] [EC:7.5.2.-]
NQK81_28070  MlaD family protein [KO:K02067]
NQK81_28075  MlaD family protein [KO:K02067]
NQK81_28080  MlaD family protein [KO:K02067]
NQK81_28085  MlaD family protein [KO:K02067]
NQK81_28090  MlaD family protein [KO:K02067]
NQK81_28095  MCE family protein [KO:K02067]
NQK81_10330  MCE family protein [KO:K02067]
NQK81_10335  MCE family protein [KO:K02067]
NQK81_10340  MCE family protein [KO:K02067]
NQK81_10345  MCE family protein [KO:K02067]
NQK81_10350  MCE family protein [KO:K02067]
NQK81_10355  MCE family protein [KO:K02067]
NQK81_19640  MCE family protein [KO:K02067]
NQK81_19645  MCE family protein [KO:K02067]
NQK81_19650  MCE family protein [KO:K02067]
NQK81_19655  MCE family protein [KO:K02067]
NQK81_19660  MCE family protein [KO:K02067]
NQK81_19665  MCE family protein [KO:K02067]
NQK81_21080  MCE family protein [KO:K02067]
NQK81_36180  MCE family protein [KO:K02067]
NQK81_36185  MCE family protein [KO:K02067]
NQK81_36190  MCE family protein [KO:K02067]
NQK81_36195  MCE family protein [KO:K02067]
NQK81_36200  MCE family protein [KO:K02067]
NQK81_36205  MCE family protein [KO:K02067]
NQK81_42685  MCE family protein [KO:K02067]
NQK81_42690  MCE family protein [KO:K02067]
NQK81_42695  MCE family protein [KO:K02067]
NQK81_42700  MCE family protein [KO:K02067]
NQK81_42705  MCE family protein [KO:K02067]
NQK81_42710  MCE family protein [KO:K02067]
NQK81_28055  ABC transporter permease [KO:K02066]
NQK81_28060  ABC transporter permease [KO:K02066]
NQK81_10360  ABC transporter permease [KO:K02066]
NQK81_10365  ABC transporter permease [KO:K02066]
NQK81_19670  ABC transporter permease [KO:K02066]
NQK81_19675  ABC transporter permease [KO:K02066]
NQK81_36210  ABC transporter permease [KO:K02066]
NQK81_36215  ABC transporter permease [KO:K02066]
NQK81_42675  ABC transporter permease [KO:K02066]
NQK81_42680  ABC transporter permease [KO:K02066]
NQK81_19680  ATP-binding cassette domain-containing protein [KO:K02065]
NQK81_28065  ATP-binding cassette domain-containing protein [KO:K02065]
NQK81_08670  BMP family ABC transporter substrate-binding protein [KO:K07335]
NQK81_18590  BMP family ABC transporter substrate-binding protein [KO:K07335]
NQK81_08660  ABC transporter permease [KO:K23535]
NQK81_18580  ABC transporter permease [KO:K23535]
NQK81_08655  ABC transporter permease [KO:K23536]
NQK81_18575  ABC transporter permease [KO:K23536]
NQK81_08665  ABC transporter ATP-binding protein [KO:K23537]
NQK81_18585  ABC transporter ATP-binding protein [KO:K23537]
NQK81_15930  substrate-binding domain-containing protein [KO:K10439]
NQK81_34060  ABC transporter substrate-binding protein [KO:K10439]
NQK81_36460  sugar ABC transporter substrate-binding protein [KO:K10439]
NQK81_15935  ABC transporter permease [KO:K10440]
NQK81_34065  ABC transporter permease [KO:K10440]
NQK81_15940  sugar ABC transporter ATP-binding protein [KO:K10441] [EC:7.5.2.7]
NQK81_44535  ABC transporter substrate-binding protein [KO:K23508]
NQK81_45080  ABC transporter substrate-binding protein [KO:K23508]
NQK81_44545  ABC transporter permease [KO:K23509]
NQK81_44550  yjfF; sugar ABC transporter permease YjfF [KO:K23509]
NQK81_45090  ABC transporter permease [KO:K23509]
NQK81_45095  ABC transporter permease [KO:K23509]
NQK81_44540  sugar ABC transporter ATP-binding protein [KO:K10820] [EC:7.5.2.9]
NQK81_45085  sugar ABC transporter ATP-binding protein [KO:K10820] [EC:7.5.2.9]
NQK81_09530  substrate-binding domain-containing protein [KO:K10543]
NQK81_09520  ABC transporter permease [KO:K10544]
NQK81_09525  ATP-binding cassette domain-containing protein [KO:K10545] [EC:7.5.2.10]
NQK81_24410  substrate-binding domain-containing protein [KO:K10552]
NQK81_24405  ABC transporter permease [KO:K10553]
NQK81_24400  ATP-binding cassette domain-containing protein [KO:K10554]
NQK81_13995  substrate-binding domain-containing protein [KO:K02040]
NQK81_22805  substrate-binding domain-containing protein [KO:K02040]
NQK81_23790  pstS; phosphate ABC transporter substrate-binding protein PstS [KO:K02040]
NQK81_13980  pstC; phosphate ABC transporter permease subunit PstC [KO:K02037]
NQK81_23785  pstC; phosphate ABC transporter permease subunit PstC [KO:K02037]
NQK81_13985  pstA; phosphate ABC transporter permease PstA [KO:K02038]
NQK81_23780  pstA; phosphate ABC transporter permease PstA [KO:K02038]
NQK81_13990  phosphate ABC transporter ATP-binding protein [KO:K02036] [EC:7.3.2.1]
NQK81_23775  pstB; phosphate ABC transporter ATP-binding protein PstB [KO:K02036] [EC:7.3.2.1]
NQK81_10620  glutamate ABC transporter substrate-binding protein [KO:K10005]
NQK81_16490  glutamate ABC transporter substrate-binding protein [KO:K10005]
NQK81_10625  amino acid ABC transporter permease [KO:K10006]
NQK81_10630  amino acid ABC transporter permease [KO:K10007]
NQK81_10615  amino acid ABC transporter ATP-binding protein [KO:K10008] [EC:7.4.2.1]
NQK81_35395  transporter substrate-binding domain-containing protein [KO:K02424]
NQK81_35390  amino acid ABC transporter permease [KO:K10009]
NQK81_35385  amino acid ABC transporter ATP-binding protein [KO:K10010] [EC:7.4.2.1]
NQK81_04590  ABC transporter substrate-binding protein [KO:K01999]
NQK81_40630  ABC transporter substrate-binding protein [KO:K01999]
NQK81_40975  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
NQK81_04595  branched-chain amino acid ABC transporter permease [KO:K01997]
NQK81_14485  branched-chain amino acid ABC transporter permease [KO:K01997]
NQK81_40640  branched-chain amino acid ABC transporter permease [KO:K01997]
NQK81_40970  branched-chain amino acid ABC transporter permease [KO:K01997]
NQK81_04600  ATP-binding cassette domain-containing protein [KO:K01995 K01998]
NQK81_14490  branched-chain amino acid ABC transporter permease [KO:K01998]
NQK81_40635  branched-chain amino acid ABC transporter permease [KO:K01998]
NQK81_40965  branched-chain amino acid ABC transporter permease [KO:K01998]
NQK81_14480  ABC transporter ATP-binding protein [KO:K01995]
NQK81_40650  ABC transporter ATP-binding protein [KO:K01995]
NQK81_40960  ABC transporter ATP-binding protein [KO:K01995]
NQK81_04605  ATP-binding cassette domain-containing protein [KO:K01996]
NQK81_14475  ABC transporter ATP-binding protein [KO:K01996]
NQK81_40645  ABC transporter ATP-binding protein [KO:K01996]
NQK81_40955  ABC transporter ATP-binding protein [KO:K01996]
NQK81_30955  ATP-binding cassette domain-containing protein [KO:K02071]
NQK81_13525  substrate-binding domain-containing protein [KO:K11959]
NQK81_13935  ABC transporter substrate-binding protein [KO:K15580]
NQK81_31180  ABC transporter substrate-binding protein [KO:K15580]
NQK81_31185  ABC transporter permease [KO:K15581]
NQK81_31190  ABC transporter permease [KO:K15582]
NQK81_31195  ABC transporter ATP-binding protein [KO:K15583]
NQK81_31200  dipeptide ABC transporter ATP-binding protein [KO:K10823]
NQK81_31810  ABC transporter family substrate-binding protein [KO:K13889]
NQK81_31815  ABC transporter permease [KO:K13890]
NQK81_31820  ABC transporter permease [KO:K13891]
NQK81_04650  ABC transporter ATP-binding protein [KO:K13892]
NQK81_24835  ABC transporter substrate-binding protein [KO:K25287]
NQK81_04795  ABC transporter substrate-binding protein [KO:K25286]
NQK81_14850  iron-siderophore ABC transporter substrate-binding protein [KO:K25286]
NQK81_04180  iron-siderophore ABC transporter substrate-binding protein [KO:K25286]
NQK81_19035  iron-siderophore ABC transporter substrate-binding protein [KO:K25286]
NQK81_04165  iron chelate uptake ABC transporter family permease subunit [KO:K23186]
NQK81_04790  iron ABC transporter permease [KO:K23186]
NQK81_19030  iron chelate uptake ABC transporter family permease subunit [KO:K23186]
NQK81_24830  iron ABC transporter permease [KO:K23186]
NQK81_04160  iron chelate uptake ABC transporter family permease subunit [KO:K23187]
NQK81_04785  iron chelate uptake ABC transporter family permease subunit [KO:K23187]
NQK81_19025  iron ABC transporter permease [KO:K23187]
NQK81_24825  iron chelate uptake ABC transporter family permease subunit [KO:K23187]
NQK81_04780  ABC transporter ATP-binding protein [KO:K23188] [EC:7.2.2.17 7.2.2.-]
NQK81_19020  ABC transporter ATP-binding protein [KO:K23188] [EC:7.2.2.17 7.2.2.-]
NQK81_36410  ABC transporter ATP-binding protein [KO:K23188] [EC:7.2.2.17 7.2.2.-]
NQK81_16105  iron-siderophore ABC transporter substrate-binding protein [KO:K23227]
NQK81_16110  iron ABC transporter permease [KO:K23228]
NQK81_16100  ABC transporter ATP-binding protein [KO:K10829] [EC:7.2.2.16]
NQK81_16085  metal ABC transporter substrate-binding protein [KO:K11601]
NQK81_16095  metal ABC transporter permease [KO:K11602]
NQK81_16090  metal ABC transporter ATP-binding protein [KO:K11603] [EC:7.2.2.5]
NQK81_33305  biotin transporter BioY [KO:K03523]
NQK81_40690  energy-coupling factor transporter transmembrane protein EcfT [KO:K16785]
NQK81_26935  ABC transporter permease [KO:K09690]
NQK81_26930  ABC transporter ATP-binding protein [KO:K09691] [EC:7.5.2.14]
NQK81_36880  ABC transporter ATP-binding protein [KO:K09691] [EC:7.5.2.14]
NQK81_12525  ABC transporter permease [KO:K09694]
NQK81_12530  ABC transporter permease [KO:K09694]
NQK81_12535  ABC transporter ATP-binding protein [KO:K09695]
NQK81_00685  ABC transporter permease [KO:K09813]
NQK81_00690  ABC transporter ATP-binding protein [KO:K09814] [EC:7.6.2.-]
NQK81_22595  ABC transporter permease [KO:K18233]
NQK81_22590  ATP-binding cassette domain-containing protein [KO:K18232]
NQK81_21550  ccsA; cytochrome c biogenesis protein CcsA [KO:K02195]
NQK81_35200  ccsA; cytochrome c biogenesis protein CcsA [KO:K02195]
NQK81_21545  heme exporter protein CcmB [KO:K02194]
NQK81_35205  heme exporter protein CcmB [KO:K02194]
NQK81_16640  ftsX; permease-like cell division protein FtsX [KO:K09811]
NQK81_16645  ftsE; cell division ATP-binding protein FtsE [KO:K09812]
NQK81_15730  ABC transporter ATP-binding protein/permease [KO:K14698] [EC:7.-.-.-]
NQK81_15735  ABC transporter ATP-binding protein/permease [KO:K14699] [EC:7.-.-.-]
NQK81_44065  ABC transporter ATP-binding protein/permease [KO:K18887]
NQK81_44060  ABC transporter ATP-binding protein/permease [KO:K18888]
NQK81_06225  ABC transporter ATP-binding protein/permease [KO:K16012]
NQK81_17715  cydC; thiol reductant ABC exporter subunit CydC [KO:K16012]
NQK81_06220  ATP-binding cassette domain-containing protein [KO:K16013]
NQK81_17710  cydD; thiol reductant ABC exporter subunit CydD [KO:K16013]
NQK81_26475  cydD; thiol reductant ABC exporter subunit CydD [KO:K16014]
NQK81_03285  abc-f; ABC-F type ribosomal protection protein [KO:K18230]
NQK81_03615  ATP-binding cassette domain-containing protein [KO:K18230]
NQK81_42910  ATP-binding cassette domain-containing protein [KO:K18230]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
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