KEGG   PATHWAY: azz02024
Entry
azz02024                    Pathway                                
Name
Quorum sensing - Azospirillum thermophilum
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
azz02024  Quorum sensing
azz02024

Other DBs
GO: 0009372
Organism
Azospirillum thermophilum [GN:azz]
Gene
DEW08_13115  RNA chaperone Hfq [KO:K03666]
DEW08_01865  anthranilate synthase component I [KO:K01657] [EC:4.1.3.27]
DEW08_01835  aminodeoxychorismate/anthranilate synthase component II [KO:K01658] [EC:4.1.3.27]
DEW08_05140  3-deoxy-7-phosphoheptulonate synthase class II [KO:K01626] [EC:2.5.1.54]
DEW08_17235  DNA-binding response regulator [KO:K07667]
DEW08_21140  trbB; P-type conjugative transfer ATPase TrbB [KO:K20527] [EC:7.4.2.8]
DEW08_06765  conjugal transfer protein TrbB [KO:K20527] [EC:7.4.2.8]
DEW08_21145  conjugal transfer protein TrbC [KO:K20528]
DEW08_06775  hypothetical protein [KO:K20529]
DEW08_21150  conjugal transfer protein TrbD [KO:K20529]
DEW08_21155  transporter [KO:K20530] [EC:7.4.2.8]
DEW08_06780  conjugal transfer protein TrbE [KO:K20530] [EC:7.4.2.8]
DEW08_21165  hypothetical protein [KO:K20266]
DEW08_06785  hypothetical protein [KO:K20266]
DEW08_21170  trbL; P-type conjugative transfer protein TrbL [KO:K07344]
DEW08_06795  conjugal transfer protein TrbL [KO:K07344]
DEW08_21175  conjugal transfer protein [KO:K20531]
DEW08_21180  trbG; P-type conjugative transfer protein TrbG [KO:K20532]
DEW08_06805  conjugal transfer protein TrbG [KO:K20532]
DEW08_21185  conjugal transfer protein TrbH [KO:K20267]
DEW08_21190  conjugal transfer protein TrbI [KO:K20533]
DEW08_06810  conjugal transfer protein TrbI [KO:K20533]
DEW08_26775  ABC transporter substrate-binding protein [KO:K02055]
DEW08_22730  spermidine/putrescine ABC transporter substrate-binding protein [KO:K02055]
DEW08_03265  ABC transporter substrate-binding protein [KO:K02055]
DEW08_26785  ABC transporter permease [KO:K02053]
DEW08_22740  polyamine ABC transporter permease [KO:K02053]
DEW08_03250  spermidine/putrescine ABC transporter permease [KO:K02053]
DEW08_21395  spermidine/putrescine ABC transporter permease [KO:K02053]
DEW08_26780  ABC transporter permease [KO:K02054]
DEW08_22735  polyamine ABC transporter substrate-binding protein [KO:K02054]
DEW08_03255  ABC transporter permease [KO:K02054]
DEW08_26770  Fe3+/spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
DEW08_22725  spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
DEW08_03260  polyamine ABC transporter ATP-binding protein [KO:K02052]
DEW08_13705  ABC transporter permease [KO:K01999]
DEW08_29125  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_26065  ABC transporter permease [KO:K01999]
DEW08_28285  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_20030  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_27005  ABC transporter substrate-binding protein [KO:K01999]
DEW08_28705  amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_20275  ABC transporter permease [KO:K01999]
DEW08_22350  branched-chain amino acid ABC transporter [KO:K01999]
DEW08_24005  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_24220  ABC transporter substrate-binding protein [KO:K01999]
DEW08_24225  ABC transporter substrate-binding protein [KO:K01999]
DEW08_07730  ABC transporter substrate-binding protein [KO:K01999]
DEW08_02500  ABC transporter substrate-binding protein [KO:K01999]
DEW08_02710  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_19110  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_27810  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_27855  ABC transporter substrate-binding protein [KO:K01999]
DEW08_00375  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DEW08_00410  ABC transporter permease [KO:K01999]
DEW08_01040  ABC transporter permease [KO:K01999]
DEW08_10265  ABC transporter substrate-binding protein [KO:K01999]
DEW08_28290  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_29320  branched-chain amino acid ABC transporter permease LivH [KO:K01997]
DEW08_26985  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_23070  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_24230  ABC transporter permease [KO:K01997 K01998]
DEW08_07725  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_02700  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_27805  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_27860  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_23980  branched-chain amino acid ABC transporter permease LivH [KO:K01997]
DEW08_09725  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_10260  ABC transporter permease [KO:K01997 K01998]
DEW08_00370  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_00405  branched-chain amino acid ABC transporter permease [KO:K01997]
DEW08_28695  ABC transporter ATP-binding protein [KO:K01995 K01998]
DEW08_29540  metal-dependent hydrolase [KO:K01995 K01998]
DEW08_00365  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_00400  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_07720  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_27800  metal-dependent hydrolase [KO:K01998]
DEW08_27865  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_23985  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_13695  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_28295  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_29315  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_26990  branched-chain amino acid ABC transporter permease [KO:K01998]
DEW08_28300  branched-chain amino acid ABC transporter ATP-binding protein [KO:K01995]
DEW08_26995  branched-chain amino acid ABC transporter ATP-binding protein [KO:K01995]
DEW08_24235  ABC transporter ATP-binding protein [KO:K01995]
DEW08_07715  livG; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG [KO:K01995]
DEW08_02690  ABC transporter ATP-binding protein [KO:K01995]
DEW08_10255  ABC transporter ATP-binding protein [KO:K01995]
DEW08_00360  ABC transporter ATP-binding protein [KO:K01995]
DEW08_00420  ABC transporter ATP-binding protein [KO:K01995]
DEW08_27870  ABC transporter ATP-binding protein [KO:K01995]
DEW08_00355  livF; branched-chain amino acid ABC transporter ATP-binding protein [KO:K01996]
DEW08_00415  ABC transporter ATP-binding protein [KO:K01996]
DEW08_07710  ABC transporter ATP-binding protein [KO:K01996]
DEW08_02715  ABC transporter ATP-binding protein [KO:K01996]
DEW08_10250  ABC transporter ATP-binding protein [KO:K01996]
DEW08_27875  ABC transporter ATP-binding protein [KO:K01996]
DEW08_23995  ABC transporter ATP-binding protein [KO:K01996]
DEW08_24240  ABC transporter ATP-binding protein [KO:K01996]
DEW08_28305  ABC transporter ATP-binding protein [KO:K01996]
DEW08_29305  ABC transporter ATP-binding protein [KO:K01996]
DEW08_27000  ABC transporter ATP-binding protein [KO:K01996]
DEW08_28690  ABC transporter ATP-binding protein [KO:K01996]
DEW08_29535  ABC transporter ATP-binding protein [KO:K01996]
DEW08_23055  livF; branched-chain amino acid ABC transporter ATP-binding protein [KO:K01996]
DEW08_18555  hypothetical protein [KO:K20276]
DEW08_02695  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
DEW08_12135  dicarboxylate--CoA ligase PimA [KO:K01897] [EC:6.2.1.3]
DEW08_09280  dicarboxylate--CoA ligase PimA [KO:K01897] [EC:6.2.1.3]
DEW08_00380  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
DEW08_22630  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
DEW08_05825  two-component system response regulator [KO:K13815]
DEW08_02790  Crp/Fnr family transcriptional regulator [KO:K10914]
DEW08_12215  Crp/Fnr family transcriptional regulator [KO:K10914]
DEW08_11230  Fur family transcriptional regulator [KO:K09823]
DEW08_24275  class I SAM-dependent methyltransferase [KO:K20331] [EC:2.1.1.349]
DEW08_07195  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
DEW08_24260  hypothetical protein [KO:K20332]
DEW08_24270  serine/threonine protein kinase [KO:K20333]
DEW08_24255  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
DEW08_24285  hypothetical protein [KO:K09936]
DEW08_24290  efflux transporter periplasmic adaptor subunit [KO:K18306]
DEW08_03600  efflux transporter periplasmic adaptor subunit [KO:K18306]
DEW08_24295  multidrug efflux protein [KO:K18307]
DEW08_03595  multidrug efflux protein [KO:K18307]
DEW08_19495  multidrug transporter [KO:K18139]
DEW08_17485  peptide ABC transporter permease [KO:K15581]
DEW08_17490  peptide ABC transporter permease [KO:K15582]
DEW08_17495  ABC transporter [KO:K10823 K15583]
DEW08_29140  peptide ABC transporter [KO:K02035]
DEW08_26220  peptide ABC transporter substrate-binding protein [KO:K02035]
DEW08_27070  peptide ABC transporter substrate-binding protein [KO:K02035]
DEW08_06320  ABC transporter substrate-binding protein [KO:K02035]
DEW08_07790  ABC transporter substrate-binding protein [KO:K02035]
DEW08_05585  ABC transporter substrate-binding protein [KO:K02035]
DEW08_18270  ABC transporter substrate-binding protein [KO:K02035]
DEW08_29145  peptide ABC transporter [KO:K02033]
DEW08_26225  ABC transporter permease [KO:K02033]
DEW08_27080  ABC transporter permease [KO:K02033]
DEW08_16635  ABC transporter permease [KO:K02033]
DEW08_06315  peptide ABC transporter [KO:K02033]
DEW08_08515  peptide ABC transporter permease [KO:K02033]
DEW08_29150  peptide ABC transporter permease [KO:K02034]
DEW08_26230  peptide ABC transporter permease [KO:K02034]
DEW08_27085  ABC transporter permease [KO:K02034]
DEW08_06310  peptide ABC transporter permease [KO:K02034]
DEW08_08510  D,D-dipeptide ABC transporter permease [KO:K02034]
DEW08_05595  ABC transporter permease [KO:K02034]
DEW08_26215  ABC transporter ATP-binding protein [KO:K02031 K02032]
DEW08_08505  peptide ABC transporter ATP-binding protein [KO:K02031]
DEW08_29170  dppD; dipeptide ABC transporter ATP-binding protein DppD [KO:K02031]
DEW08_27065  glutathione ABC transporter ATP-binding protein GsiA [KO:K02031 K02032]
DEW08_29175  peptide ABC transporter ATP-binding protein [KO:K02032]
DEW08_08940  membrane protein insertase YidC [KO:K03217]
DEW08_22505  hypothetical protein [KO:K14645] [EC:3.4.21.-]
DEW08_02130  secD; protein translocase subunit SecD [KO:K12257]
DEW08_10330  preprotein translocase subunit SecE [KO:K03073]
DEW08_01880  preprotein translocase subunit SecG [KO:K03075]
DEW08_10495  preprotein translocase subunit SecY [KO:K03076]
DEW08_02125  yajC; preprotein translocase subunit YajC [KO:K03210]
DEW08_07895  preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
DEW08_07040  protein-export chaperone SecB [KO:K03071]
DEW08_08900  signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
PMID:25824838
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
  Journal
Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
Reference
PMID:19363118
  Authors
Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
  Title
Virulence gene regulation by the agr system in Clostridium perfringens.
  Journal
J Bacteriol 191:3919-27 (2009)
DOI:10.1128/JB.01455-08
Reference
PMID:22736963
  Authors
Li YH, Tian X
  Title
Quorum sensing and bacterial social interactions in biofilms.
  Journal
Sensors (Basel) 12:2519-38 (2012)
DOI:10.3390/s120302519
Reference
PMID:22407687
  Authors
Berg KH, Biornstad TJ, Johnsborg O, Havarstein LS
  Title
Properties and biological role of streptococcal fratricins.
  Journal
Appl Environ Microbiol 78:3515-22 (2012)
DOI:10.1128/AEM.00098-12
Reference
PMID:25475081
  Authors
Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP
  Title
Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
  Journal
J Oral Microbiol 6:26189 (2014)
DOI:10.3402/jom.v6.26189
Reference
PMID:25309879
  Authors
Jimenez JC, Federle MJ
  Title
Quorum sensing in group A Streptococcus.
  Journal
Front Cell Infect Microbiol 4:127 (2014)
DOI:10.3389/fcimb.2014.00127
Reference
PMID:24118108
  Authors
Cook LC, Federle MJ
  Title
Peptide pheromone signaling in Streptococcus and Enterococcus.
  Journal
FEMS Microbiol Rev 38:473-92 (2014)
DOI:10.1111/1574-6976.12046
Reference
PMID:9680220
  Authors
Podbielski A, Leonard BA
  Title
The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease.
  Journal
Mol Microbiol 28:1323-34 (1998)
DOI:10.1046/j.1365-2958.1998.00898.x
Reference
PMID:8885277
  Authors
Podbielski A, Pohl B, Woischnik M, Korner C, Schmidt KH, Rozdzinski E, Leonard BA
  Title
Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production.
  Journal
Mol Microbiol 21:1087-99 (1996)
DOI:10.1046/j.1365-2958.1996.661421.x
Reference
PMID:22636768
  Authors
Anbalagan S, Dmitriev A, McShan WM, Dunman PM, Chaussee MS
  Title
Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.
  Journal
J Bacteriol 194:3961-71 (2012)
DOI:10.1128/JB.06709-11
Reference
PMID:22016844
  Authors
Clewell DB
  Title
Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
  Journal
Mob Genet Elements 1:38-54 (2011)
DOI:10.4161/mge.1.1.15409
Reference
PMID:20734751
  Authors
Wardal E, Sadowy E, Hryniewicz W
  Title
Complex nature of enterococcal pheromone-responsive plasmids.
  Journal
Pol J Microbiol 59:79-87 (2010)
Reference
PMID:19683678
  Authors
Roux A, Payne SM, Gilmore MS
  Title
Microbial telesensing: probing the environment for friends, foes, and food.
  Journal
Cell Host Microbe 6:115-24 (2009)
DOI:10.1016/j.chom.2009.07.004
Reference
PMID:25089349
  Authors
Slamti L, Perchat S, Huillet E, Lereclus D
  Title
Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
  Journal
Toxins (Basel) 6:2239-55 (2014)
DOI:10.3390/toxins6082239
Reference
PMID:20030732
  Authors
Lopez D, Kolter R
  Title
Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis.
  Journal
FEMS Microbiol Rev 34:134-49 (2010)
DOI:10.1111/j.1574-6976.2009.00199.x
Reference
PMID:12897006
  Authors
Stephenson S, Mueller C, Jiang M, Perego M
  Title
Molecular analysis of Phr peptide processing in Bacillus subtilis.
  Journal
J Bacteriol 185:4861-71 (2003)
DOI:10.1128/JB.185.16.4861-4871.2003
Reference
PMID:17666034
  Authors
Lanigan-Gerdes S, Dooley AN, Faull KF, Lazazzera BA
  Title
Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
  Journal
Mol Microbiol 65:1321-33 (2007)
DOI:10.1111/j.1365-2958.2007.05869.x
Reference
PMID:15374644
  Authors
Kleerebezem M
  Title
Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis.
  Journal
Peptides 25:1405-14 (2004)
DOI:10.1016/j.peptides.2003.10.021
Reference
PMID:23125205
  Authors
Rutherford ST, Bassler BL
  Title
Bacterial quorum sensing: its role in virulence and possibilities for its control.
  Journal
Cold Spring Harb Perspect Med 2:a012427 (2012)
DOI:10.1101/cshperspect.a012427
Reference
PMID:23471618
  Authors
LaSarre B, Federle MJ
  Title
Exploiting quorum sensing to confuse bacterial pathogens.
  Journal
Microbiol Mol Biol Rev 77:73-111 (2013)
DOI:10.1128/MMBR.00046-12
Reference
PMID:18781869
  Authors
Sifri CD
  Title
Healthcare epidemiology: quorum sensing: bacteria talk sense.
  Journal
Clin Infect Dis 47:1070-6 (2008)
DOI:10.1086/592072
Related
pathway
azz02040  Flagellar assembly
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ko02024   
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