KEGG   PATHWAY: bwd00061
Entry
bwd00061                    Pathway                                
Name
Fatty acid biosynthesis - Bacillus wiedmannii
Class
Metabolism; Lipid metabolism
Pathway map
bwd00061  Fatty acid biosynthesis
bwd00061

Module
bwd_M00082  Fatty acid biosynthesis, initiation [PATH:bwd00061]
bwd_M00083  Fatty acid biosynthesis, elongation [PATH:bwd00061]
bwd_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:bwd00061]
Other DBs
GO: 0006633
Organism
Bacillus wiedmannii [GN:bwd]
Gene
CT694_17020  acetyl-CoA carboxylase carboxyltransferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
CT694_24575  acetyl-CoA carboxylase carboxyltransferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
CT694_22535  accB; acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
CT694_13350  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit [KO:K02160]
CT694_22530  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
CT694_13345  biotin carboxylase [KO:K01961] [EC:6.4.1.2 6.3.4.14]
CT694_24580  acetyl-CoA carboxylase carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
CT694_20730  fabD; [acyl-carrier-protein] S-malonyltransferase [KO:K00645] [EC:2.3.1.39]
CT694_09780  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
CT694_06400  3-oxoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
CT694_06405  fabF; beta-ketoacyl-[acyl-carrier-protein] synthase II [KO:K09458] [EC:2.3.1.179]
CT694_32635  3-oxoacyl-ACP synthase [KO:K09458] [EC:2.3.1.179]
CT694_20725  3-oxoacyl-[acyl-carrier-protein] reductase [KO:K00059] [EC:1.1.1.100]
CT694_18910  3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
CT694_01015  3-ketoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CT694_24715  fabG; NAD(P)-dependent oxidoreductase [KO:K00059] [EC:1.1.1.100]
CT694_32605  fabG; 3-oxoacyl-[acyl-carrier-protein] reductase [KO:K00059] [EC:1.1.1.100]
CT694_17675  3-ketoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CT694_20390  3-ketoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CT694_30300  short-chain dehydrogenase [KO:K00059] [EC:1.1.1.100]
CT694_09895  short-chain dehydrogenase [KO:K00059] [EC:1.1.1.100]
CT694_15460  beta-hydroxyacyl-ACP dehydratase [KO:K02372] [EC:4.2.1.59]
CT694_32615  3-hydroxyacyl-ACP dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
CT694_28320  fabZ; beta-hydroxyacyl-ACP dehydratase [KO:K02372] [EC:4.2.1.59]
CT694_06625  enoyl-[acyl-carrier-protein] reductase FabI [KO:K00208] [EC:1.3.1.9 1.3.1.10]
CT694_16735  acyl-ACP desaturase [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
CT694_06025  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
CT694_24200  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
bwd00020  Citrate cycle (TCA cycle)
bwd00071  Fatty acid degradation
bwd00410  beta-Alanine metabolism
bwd00561  Glycerolipid metabolism
bwd00564  Glycerophospholipid metabolism
bwd00620  Pyruvate metabolism
bwd00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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