KEGG   PATHWAY: cabk02024
Entry
cabk02024                   Pathway                                
Name
Quorum sensing - Caballeronia sp. NK8
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
cabk02024  Quorum sensing
cabk02024

Other DBs
GO: 0009372
Organism
Caballeronia sp. NK8 [GN:cabk]
Gene
NK8_16040  hfq; RNA chaperone Hfq [KO:K03666]
NK8_46130  hfq; RNA chaperone Hfq [KO:K03666]
NK8_24420  anthranilate synthase component I [KO:K01657] [EC:4.1.3.27]
NK8_24430  gamma-glutamyl-gamma-aminobutyrate hydrolase family protein [KO:K01658] [EC:4.1.3.27]
NK8_21930  glycosyltransferase family 2 protein [KO:K12990] [EC:2.4.1.-]
NK8_03670  aroG; 3-deoxy-7-phosphoheptulonate synthase AroG [KO:K01626] [EC:2.5.1.54]
NK8_61390  3-deoxy-7-phosphoheptulonate synthase [KO:K01626] [EC:2.5.1.54]
NK8_71920  two-component sensor histidine kinase [KO:K07645] [EC:2.7.13.3]
NK8_35650  flhD; flagellar transcriptional regulator FlhD [KO:K02403]
NK8_69900  flagellar transcriptional regulator FlhD [KO:K02403]
NK8_84940  flagellar transcriptional regulator FlhD [KO:K02403]
NK8_01190  flhD; flagellar transcriptional regulator FlhD [KO:K02403]
NK8_35660  flhC; flagellar transcriptional regulator FlhC [KO:K02402]
NK8_69890  flhC; flagellar transcriptional regulator FlhC [KO:K02402]
NK8_84930  flhC; flagellar transcriptional regulator FlhC [KO:K02402]
NK8_01200  flhC; flagellar transcriptional regulator FlhC [KO:K02402]
NK8_09150  kdpE; two-component system response regulator KdpE [KO:K07667]
NK8_74280  VirB3 family type IV secretion system protein [KO:K20529]
NK8_85490  hypothetical protein [KO:K20529]
NK8_74270  type IV secretion system protein VirB4 [KO:K20530] [EC:7.4.2.8]
NK8_85480  type IV secretion system protein VirB4 [KO:K20530] [EC:7.4.2.8]
NK8_75380  type VI secretion protein [KO:K20531]
NK8_86290  type VI secretion protein [KO:K20531]
NK8_75370  TrbG/VirB9 family P-type conjugative transfer protein [KO:K20532]
NK8_86280  TrbG/VirB9 family P-type conjugative transfer protein [KO:K20532]
NK8_75360  TrbI/VirB10 family protein [KO:K20533]
NK8_86270  TrbI/VirB10 family protein [KO:K20533]
NK8_33710  extracellular solute-binding protein [KO:K02055]
NK8_35290  extracellular solute-binding protein [KO:K02055]
NK8_45240  extracellular solute-binding protein [KO:K02055]
NK8_46880  extracellular solute-binding protein [KO:K02055]
NK8_57150  ABC transporter substrate-binding protein [KO:K02055]
NK8_69340  ABC transporter substrate-binding protein [KO:K02055]
NK8_76630  extracellular solute-binding protein [KO:K02055]
NK8_78650  ABC transporter substrate-binding protein [KO:K02055]
NK8_80200  extracellular solute-binding protein [KO:K02055]
NK8_81330  ABC transporter substrate-binding protein [KO:K02055]
NK8_33690  ABC transporter permease subunit [KO:K02053]
NK8_35320  ABC transporter permease subunit [KO:K02053]
NK8_45220  ABC transporter permease subunit [KO:K02053]
NK8_46900  ABC transporter permease subunit [KO:K02053]
NK8_57110  ABC transporter permease [KO:K02053]
NK8_69320  ABC transporter permease subunit [KO:K02053 K02054]
NK8_76650  ABC transporter permease subunit [KO:K02053]
NK8_78620  ABC transporter permease subunit [KO:K02053]
NK8_80230  ABC transporter permease [KO:K02053]
NK8_81350  ABC transporter permease [KO:K02053]
NK8_33700  ABC transporter permease [KO:K02054]
NK8_35310  ABC transporter permease subunit [KO:K02054]
NK8_45230  ABC transporter permease subunit [KO:K02054]
NK8_46890  ABC transporter permease subunit [KO:K02054]
NK8_57100  ABC transporter permease [KO:K02054]
NK8_76640  ABC transporter permease subunit [KO:K02054]
NK8_78610  ABC transporter permease subunit [KO:K02054]
NK8_80220  ABC transporter permease subunit [KO:K02054]
NK8_81340  ABC transporter permease [KO:K02054]
NK8_33720  ATP-binding cassette domain-containing protein [KO:K02052]
NK8_35300  ATP-binding cassette domain-containing protein [KO:K02052]
NK8_45210  ATP-binding cassette domain-containing protein [KO:K02052]
NK8_46870  ATP-binding cassette domain-containing protein [KO:K02052]
NK8_57090  ABC transporter ATP-binding protein [KO:K02052]
NK8_69330  ABC transporter ATP-binding protein [KO:K02052]
NK8_76660  ATP-binding cassette domain-containing protein [KO:K02052]
NK8_78580  polyamine ABC transporter ATP-binding protein [KO:K02052]
NK8_80210  ATP-binding cassette domain-containing protein [KO:K02052]
NK8_81320  ABC transporter ATP-binding protein [KO:K02052]
NK8_06260  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
NK8_06420  ABC transporter substrate-binding protein [KO:K01999]
NK8_17770  ABC transporter substrate-binding protein [KO:K01999]
NK8_27600  ABC transporter substrate-binding protein [KO:K01999]
NK8_27840  ABC transporter substrate-binding protein [KO:K01999]
NK8_27850  ABC transporter substrate-binding protein [KO:K01999]
NK8_27880  ABC transporter substrate-binding protein [KO:K01999]
NK8_28680  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
NK8_29970  ABC transporter substrate-binding protein [KO:K01999]
NK8_36620  ABC transporter substrate-binding protein [KO:K01999]
NK8_39100  ABC transporter substrate-binding protein [KO:K01999]
NK8_45110  ABC transporter substrate-binding protein [KO:K01999]
NK8_50100  transporter substrate-binding protein [KO:K01999]
NK8_54590  ABC transporter substrate-binding protein [KO:K01999]
NK8_57160  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
NK8_60180  ABC transporter substrate-binding protein [KO:K01999]
NK8_61460  ABC transporter substrate-binding protein [KO:K01999]
NK8_69360  ABC transporter substrate-binding protein [KO:K01999]
NK8_76280  ABC transporter substrate-binding protein [KO:K01999]
NK8_77830  ABC transporter substrate-binding protein [KO:K01999]
NK8_81180  ABC transporter substrate-binding protein [KO:K01999]
NK8_01500  ABC transporter substrate-binding protein [KO:K01999]
NK8_06270  branched-chain amino acid ABC transporter permease [KO:K01997]
NK8_19020  branched-chain amino acid ABC transporter permease [KO:K01997]
NK8_27830  branched-chain amino acid ABC transporter permease [KO:K01997]
NK8_27870  branched-chain amino acid ABC transporter permease [KO:K01997]
NK8_36610  branched-chain amino acid ABC transporter permease [KO:K01997]
NK8_39130  ABC transporter permease [KO:K01997 K01998]
NK8_60170  branched-chain amino acid ABC transporter permease [KO:K01997]
NK8_61450  branched-chain amino acid ABC transporter permease [KO:K01997]
NK8_76310  ABC transporter permease [KO:K01997 K01998]
NK8_77870  branched-chain amino acid ABC transporter permease [KO:K01997]
NK8_06280  ABC transporter ATP-binding protein [KO:K01998]
NK8_19010  branched-chain amino acid ABC transporter permease [KO:K01995 K01998]
NK8_27820  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
NK8_27860  branched-chain amino acid ABC transporter permease [KO:K01998]
NK8_36600  ATP-binding cassette domain-containing protein [KO:K01995 K01998]
NK8_60160  branched-chain amino acid ABC transporter permease [KO:K01998]
NK8_61440  branched-chain amino acid ABC transporter permease [KO:K01998]
NK8_69380  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
NK8_77880  branched-chain amino acid ABC transporter permease [KO:K01998]
NK8_06290  ABC transporter ATP-binding protein [KO:K01995]
NK8_19000  ATP-binding cassette domain-containing protein [KO:K01995]
NK8_27900  ABC transporter ATP-binding protein [KO:K01995]
NK8_39120  ATP-binding cassette domain-containing protein [KO:K01995]
NK8_46360  hypothetical protein [KO:K01995]
NK8_60150  ATP-binding cassette domain-containing protein [KO:K01995]
NK8_76300  ATP-binding cassette domain-containing protein [KO:K01995]
NK8_77850  ATP-binding cassette domain-containing protein [KO:K01995]
NK8_06300  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_18990  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_27810  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_27890  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_36590  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_39110  ABC transporter ATP-binding protein [KO:K01996]
NK8_46350  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_60140  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_69390  ABC transporter ATP-binding protein [KO:K01996]
NK8_76290  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_77860  ATP-binding cassette domain-containing protein [KO:K01996]
NK8_16730  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
NK8_24240  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
NK8_46280  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
NK8_05690  transcriptional repressor [KO:K09823]
NK8_09200  helix-turn-helix domain-containing protein [KO:K20329]
NK8_38700  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
NK8_07860  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
NK8_05560  efflux transporter outer membrane subunit [KO:K18139]
NK8_05590  efflux transporter outer membrane subunit [KO:K18139]
NK8_54520  efflux transporter outer membrane subunit [KO:K18139]
NK8_37260  peptide ABC transporter substrate-binding protein [KO:K15580]
NK8_37250  oppB; oligopeptide ABC transporter permease OppB [KO:K15581]
NK8_37240  ABC transporter permease subunit [KO:K15582]
NK8_37230  ATP-binding cassette domain-containing protein [KO:K15583]
NK8_56010  ATP-binding cassette domain-containing protein [KO:K15583]
NK8_37220  oppF; murein tripeptide/oligopeptide ABC transporter ATP binding protein OppF [KO:K10823]
NK8_05980  ABC transporter substrate-binding protein [KO:K02035]
NK8_11810  ABC transporter substrate-binding protein [KO:K02035]
NK8_48830  ABC transporter substrate-binding protein [KO:K02035]
NK8_57430  ABC transporter substrate-binding protein [KO:K02035]
NK8_78440  ABC transporter substrate-binding protein [KO:K02035]
NK8_78490  ABC transporter substrate-binding protein [KO:K02035]
NK8_05970  ABC transporter permease subunit [KO:K02033]
NK8_11820  ABC transporter permease [KO:K02033]
NK8_48820  ABC transporter permease subunit [KO:K02033]
NK8_56030  ABC transporter permease [KO:K02033]
NK8_57420  ABC transporter permease subunit [KO:K02033]
NK8_78500  ABC transporter permease subunit [KO:K02033]
NK8_05960  ABC transporter permease subunit [KO:K02034]
NK8_11830  ABC transporter permease subunit [KO:K02034]
NK8_48810  ABC transporter permease subunit [KO:K02034]
NK8_56020  ABC transporter permease subunit [KO:K02034]
NK8_57410  ABC transporter permease subunit [KO:K02034]
NK8_78510  ABC transporter permease subunit [KO:K02034]
NK8_05950  dipeptide ABC transporter ATP-binding protein [KO:K02031 K02032]
NK8_11840  ATP-binding cassette domain-containing protein [KO:K02031]
NK8_78520  dipeptide ABC transporter ATP-binding protein [KO:K02031 K02032]
NK8_11850  ATP-binding cassette domain-containing protein [KO:K02032]
NK8_56000  ATP-binding cassette domain-containing protein [KO:K02032]
NK8_29180  yidC; membrane protein insertase YidC [KO:K03217]
NK8_25940  secE; preprotein translocase subunit SecE [KO:K03073]
NK8_17720  secG; preprotein translocase subunit SecG [KO:K03075]
NK8_25600  secY; preprotein translocase subunit SecY [KO:K03076]
NK8_03500  yajC; preprotein translocase subunit YajC [KO:K03210]
NK8_24030  secA; preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
NK8_02280  ftsY; signal recognition particle-docking protein FtsY [KO:K03110]
NK8_01950  secB; protein-export chaperone SecB [KO:K03071]
NK8_23810  ffh; signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
NK8_40450  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
NK8_60000  phosphoesterase [KO:K01114] [EC:3.1.4.3]
NK8_81690  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
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Related
pathway
cabk02040  Flagellar assembly
KO pathway
ko02024   
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