Entry Name ABC transporters - Escherichia coli clone D i14
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Escherichia coli clone D i14 [GN:
elc ]
Gene i14_0454 tauA; taurine transporter substrate binding subunit [KO:K15551 ]
i14_0987 ycbO; alkanesulfonate transporter substrate-binding component [KO:K15553 ]
i14_0985 ssuC; alkanesulfonate transporter permease subunit [KO:K15554 ]
i14_0803 modF; putative molybdenum transport ATP-binding protein [KO:K05776 ]
i14_0074 tbpA; thiamine transporter substrate binding subunit [KO:K02064 ]
i14_1280 potC; spermidine/putrescine ABC transporter membrane [KO:K11070 ]
i14_1346 potB; spermidine/putrescine ABC transporter membrane [KO:K11071 ]
i14_2962 proX; glycine betaine transporter periplasmic subunit [KO:K02002 ]
i14_2961 proW; glycine betaine transporter membrane protein [KO:K02001 ]
i14_4589 malE; maltose ABC transporter periplasmic protein [KO:K10108 ]
i14_4590 malK; maltose/maltodextrin transporter [KO:K10111 ] [EC:7.5.2.-]
i14_1617 ycjV; ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
i14_2865 yphF; ABC transporter periplasmic-binding protein [KO:K23545 ]
i14_3639 yrbF; putative ABC transporter ATP-binding protein [KO:K02065 ]
i14_4828 ytfQ; ABC transporter periplasmic-binding protein [KO:K23508 ]
i14_4831 yjfF; inner membrane ABC transporter permease protein [KO:K23509 ]
i14_4055 xylH; xylose transport system permease protein xylH [KO:K10544 ]
i14_3912 ugpB; glycerol-3-phosphate transporter periplasmic component [KO:K05813 ]
i14_3911 ugpA; glycerol-3-phosphate transporter permease component [KO:K05814 ]
i14_3910 ugpE; glycerol-3-phosphate transporter membrane component [KO:K05815 ]
i14_4244 pstC; phosphate transporter permease subunit PstC [KO:K02037 ]
i14_4243 pstA; phosphate transporter permease subunit PtsA [KO:K02038 ]
i14_2647 hisM; histidine transport system permease protein [KO:K10015 ]
i14_2648 hisQ; histidine transport system permease protein [KO:K10016 ]
i14_2649 hisJ; histidine-binding periplasmic protein precursor [KO:K10014 ]
i14_0860 glnH; glutamine ABC transporter periplasmic protein [KO:K10036 ]
i14_0708 ybeJ; glutamate and aspartate transporter subunit [KO:K10001 ]
i14_0706 gltK; glutamate/aspartate transport system permease component [KO:K10002 ]
i14_0707 gltJ; glutamate/aspartate transport system permease component [KO:K10003 ]
i14_3718 yhdX; amino-acid ABC transporter permease protein [KO:K09970 ]
i14_3719 yhdY; amino-acid ABC transporter permease protein [KO:K09971 ]
i14_2148 yecS; amino-acid ABC transporter permease protein [KO:K10009 ]
i14_3917 livH; branched-chain amino acid transporter permease [KO:K01997 ]
i14_3916 livM; leucine/isoleucine/valine transporter permease [KO:K01998 ]
i14_0220 metQ; DL-methionine transporter substrate-binding protein [KO:K02073 ]
i14_0222 metN; DL-methionine transporter ATP-binding subunit [KO:K02071 ]
i14_1542 oppC; oligopeptide transport system permease protein [KO:K15582 ]
i14_1543 oppD; oligopeptide transporter ATP-binding component [KO:K15583 ]
i14_1544 oppF; oligopeptide transport ATP-binding protein oppF [KO:K10823 ]
i14_1599 sapB; peptide transport system permease protein sapB [KO:K19227 ]
i14_1598 sapC; peptide transport system permease protein sapC [KO:K19228 ]
i14_1597 sapD; peptide transport system ATP-binding protein [KO:K19229 ]
i14_1596 sapF; peptide transport system ATP-binding protein [KO:K19230 ]
i14_3939 nikA; nickel-binding periplasmic protein precursor [KO:K15584 ]
i14_0878 yliA; glutathione transporter ATP-binding protein [KO:K13892 ]
i14_0651 fepD; iron-enterobactin transporter membrane protein [KO:K23186 ]
i14_0172 fhuD; iron-hydroxamate transporter substrate-binding subunit [KO:K23227 ]
i14_0173 fhuB; iron-hydroxamate transporter permease subunit [KO:K23228 ]
i14_1272 lolC; outer membrane-specific lipoprotein transporter [KO:K09808 ]
i14_1274 lolE; outer membrane-specific lipoprotein transporter [KO:K09808 ]
i14_1273 lolD; lipoprotein transporter ATP-binding subunit [KO:K09810 ] [EC:7.6.2.-]
i14_2239 putative inner membrane ABC-transporter [KO:K14698 ] [EC:7.-.-.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
