Entry
Name
ABC transporters - Escherichia coli LF82
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Escherichia coli LF82 [GN:
elf ]
Gene
LF82_2190 ssuC; aliphatic sulfonates transport permease protein ssu [KO:K15554 ]
LF82_1373 modB; Molybdenum transport system permease protein modB [KO:K02018 ]
LF82_2256 thiP; Thiamine transport system permease protein thiP [KO:K02063 ]
LF82_1687 potD; Spermidine/putrescine-binding periplasmic protein [KO:K11069 ]
LF82_1686 potC; Spermidine/putrescine transport system permease protein [KO:K11070 ]
LF82_1685 potB; Spermidine/putrescine transport system permease protein [KO:K11071 ]
LF82_1692 potI; Putrescine transport system permease protein potI [KO:K11074 ]
LF82_1691 potH; Putrescine transport system permease protein potH [KO:K11075 ]
LF82_1736 proW; glycine betaine/L-proline transport system permease [KO:K02001 ]
LF82_3004 yehW; Inner membrane ABC transporter permease protein yehW [KO:K05846 ]
LF82_3006 yehy; Inner membrane ABC transporter permease protein yehy [KO:K05846 ]
LF82_1261 malK; Maltose/maltodextrin import ATP-binding protein malK [KO:K10111 ] [EC:7.5.2.-]
LF82_2778 ycjV; Uncharacterized ABC transporter ATP-binding protein ycjV [KO:K10112 ] [EC:7.5.2.-]
LF82_3634 yphF; ABC transporter periplasmic-binding protein yphF [KO:K23545 ]
LF82_3633 yphE; Uncharacterized ABC transporter ATP-binding protein yphE [KO:K23547 ]
LF82_3689 yrbF; Uncharacterized ABC transporter ATP-binding protein [KO:K02065 ]
LF82_0112 araH; L-arabinose transport system permease protein araH [KO:K10538 ]
LF82_3714 ytfQ; ABC transporter periplasmic-binding protein ytfQ [KO:K23508 ]
LF82_3459 yjfF; Inner membrane ABC transporter permease protein yjfF [KO:K23509 ]
LF82_3716 ytfT; Inner membrane ABC transporter permease protein ytfT [KO:K23509 ]
LF82_1340 mglC; Galactoside transport system permease protein mglC [KO:K10541 ]
LF82_0077 alsC; D-allose transport system permease protein alsC [KO:K10550 ]
LF82_2360 ugpB; sn-glycerol-3-phosphate-binding periplasmic protein ugpB [KO:K05813 ]
LF82_2359 ugpA; sn-glycerol-3-phosphate transport system permease [KO:K05814 ]
LF82_2362 ugpE; sn-glycerol-3-phosphate transport system permease [KO:K05815 ]
LF82_1761 pstC; Phosphate transport system permease protein pstC [KO:K02037 ]
LF82_1759 pstA; Phosphate transport system permease protein pstA [KO:K02038 ]
LF82_1644 phnE; Phosphonates transport system permease protein phnE [KO:K02042 ]
LF82_0129 argT; Lysine-arginine-ornithine-binding periplasmic protein [KO:K10013 ]
LF82_1007 hisM; Histidine transport system permease protein hisM [KO:K10015 ]
LF82_1009 hisQ; Histidine transport system permease protein hisQ [KO:K10016 ]
LF82_0854 glnP; glutamine transport system permease protein glnP [KO:K10037 ]
LF82_0155 artM; Arginine transport system permease protein artM [KO:K09998 ]
LF82_0157 artQ; Arginine transport system permease protein artQ [KO:K09999 ]
LF82_0878 gltI; glutamate/aspartate periplasmic-binding protein [KO:K10001 ]
LF82_0880 gltK; glutamate/aspartate transport system permease protein [KO:K10002 ]
LF82_0879 gltJ; glutamate/aspartate transport system permease protein [KO:K10003 ]
LF82_3270 yhdW; amino-acid ABC transporter-binding protein yhdW [KO:K09969 ]
LF82_3272 yhdY; Inner membrane amino-acid ABC transporter permease [KO:K09971 ]
LF82_2948 yecS; Inner membrane amino-acid ABC transporter permease [KO:K10009 ]
LF82_1203 livH; High-affinity branched-chain amino acid transport [KO:K01997 ]
LF82_1206 livM; High-affinity branched-chain amino acid transport system [KO:K01998 ]
LF82_1202 livG; High-affinity branched-chain amino acid transport [KO:K01995 ]
LF82_1201 livF; High-affinity branched-chain amino acid transport [KO:K01996 ]
LF82_1324 metI; D-methionine transport system permease protein metI [KO:K02072 ]
LF82_1571 oppB; Oligopeptide transport system permease protein oppB [KO:K15581 ]
LF82_1572 oppC; Oligopeptide transport system permease protein oppC [KO:K15582 ]
LF82_1573 oppD; Oligopeptide transport ATP-binding protein oppD [KO:K15583 ]
LF82_1574 oppF; Oligopeptide transport ATP-binding protein oppF [KO:K10823 ]
LF82_0516 dppB; Dipeptide transport system permease protein dppB [KO:K12369 ]
LF82_0517 dppC; Dipeptide transport system permease protein dppC [KO:K12370 ]
LF82_2086 sapD; Peptide transport system ATP-binding protein sapD [KO:K19229 ]
LF82_2087 sapF; Peptide transport system ATP-binding protein sapF [KO:K19230 ]
LF82_0934 gsiC; glutathione transport system permease protein gsiC [KO:K13890 ]
LF82_0935 gsiD; glutathione transport system permease protein gsiD [KO:K13891 ]
LF82_3025 yejB; Inner membrane ABC transporter permease protein yejB [KO:K13894 ]
LF82_3026 yejE; Inner membrane ABC transporter permease protein yejE [KO:K13895 ]
LF82_3027 yejF; Uncharacterized ABC transporter ATP-binding protein yejF [KO:K13896 ]
LF82_0643 fepD; Ferric enterobactin transport system permease protein [KO:K23186 ]
LF82_0645 fepG; Ferric enterobactin transport system permease protein [KO:K23187 ]
LF82_0651 fhuB; Ferrichrome transport system permease protein fhuB [KO:K23228 ]
LF82_0249 btuC; Vitamin B12 import system permease protein btuC [KO:K06073 ]
LF82_3726 znuB; High-affinity zinc uptake system membrane protein znuB [KO:K09816 ]
LF82_457 ATP-binding protein of ABC transport system (ABC transporter ATP-binding subunit) [KO:K16786 ] [EC:7.-.-.-]
LF82_458 ATP-binding protein of ABC transportsyste m [KO:K16787 ] [EC:7.-.-.-]
LF82_462 Polysialic acid capsule synthesis protein KpsE, Capsule polysaccharide export inner-membrane protein kpsE [KO:K10107 ]
LF82_1213 lolC; Lipoprotein-releasing system transmembrane protein lolC [KO:K09808 ]
LF82_1215 lolE; Lipoprotein-releasing system transmembrane protein lolE [KO:K09808 ]
LF82_1214 lolD; Lipoprotein-releasing system ATP-binding protein lolD [KO:K09810 ] [EC:7.6.2.-]
LF82_1285 mdlA; Multidrug resistance-like ATP-binding protein mdlA [KO:K18889 ]
LF82_1286 mdlB; Multidrug resistance-like ATP-binding protein mdlB [KO:K18890 ]
LF82_1253 macB; Macrolide export ATP-binding/permease protein macB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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