KEGG   PATHWAY: elx02020
Entry
elx02020                    Pathway                                
Name
Two-component system - Escherichia coli O157:H7 Xuzhou21 (EHEC)
Description
Two-component signal transduction systems enable bacteria to sense, respond, and adapt to changes in their environment or in their intracellular state. Each two-component system consists of a sensor protein-histidine kinase (HK) and a response regulator (RR). In the prototypical two-component pathway, the sensor HK phosphorylates its own conserved His residue in response to a signal(s) in the environment. Subsequently, the phosphoryl group of HK is transferred onto a specific Asp residue on the RR. The activated RR can then effect changes in cellular physiology, often by regulating gene expression. Two-component pathways thus often enable cells to sense and respond to stimuli by inducing changes in transcription.
Class
Environmental Information Processing; Signal transduction
Pathway map
elx02020  Two-component system
elx02020

Other DBs
GO: 0000160
Organism
Escherichia coli O157:H7 Xuzhou21 (EHEC) [GN:elx]
Gene
CDCO157_0438  phoR; phosphate regulon sensor protein [KO:K07636] [EC:2.7.13.3]
CDCO157_0437  transcriptional regulator PhoB [KO:K07657]
CDCO157_0421  alkaline phosphatase [KO:K01077] [EC:3.1.3.1]
CDCO157_4400  phosphate ABC transporter periplasmic substrate-binding protein PstS [KO:K02040]
CDCO157_1533  sensor protein PhoQ [KO:K07637] [EC:2.7.13.3]
CDCO157_1534  DNA-binding transcriptional regulator PhoP [KO:K07660]
CDCO157_3599  putative virulence-related membrane protein [KO:K07804]
CDCO157_3987  envZ; osmolarity sensor protein [KO:K07638] [EC:2.7.13.3]
CDCO157_3988  ompR; osmolarity response regulator [KO:K07659]
CDCO157_2868  outer membrane porin protein C [KO:K09475]
CDCO157_0988  outer membrane protein F [KO:K09476]
CDCO157_4576  cpxA; two-component sensor protein [KO:K07640] [EC:2.7.13.3]
CDCO157_4577  DNA-binding transcriptional regulator CpxR [KO:K07662]
CDCO157_3719  hypothetical protein [KO:K25864]
CDCO157_2152  sensor protein RstB [KO:K07639] [EC:2.7.13.3]
CDCO157_2151  DNA-binding transcriptional regulator RstA [KO:K07661]
CDCO157_0163  serine endoprotease [KO:K04771] [EC:3.4.21.107]
CDCO157_5041  sensory histidine kinase CreC [KO:K07641] [EC:2.7.13.3]
CDCO157_5040  DNA-binding response regulator CreB [KO:K07663]
CDCO157_2663  signal transduction histidine-protein kinase BaeS [KO:K07642] [EC:2.7.13.3]
CDCO157_2664  DNA-binding transcriptional regulator BaeR [KO:K07664]
CDCO157_2659  multidrug efflux system subunit MdtA [KO:K07799]
CDCO157_2660  multidrug efflux system subunit MdtB [KO:K07788]
CDCO157_2661  multidrug efflux system subunit MdtC [KO:K07789]
CDCO157_2662  multidrug efflux system protein MdtE [KO:K18326]
CDCO157_3097  aminoglycoside/multidrug efflux system [KO:K18324]
CDCO157_4779  sensor protein BasS/PmrB [KO:K07643] [EC:2.7.13.3]
CDCO157_4780  DNA-binding transcriptional regulator BasR [KO:K07771]
CDCO157_2904  UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase [KO:K07806] [EC:2.6.1.87]
CDCO157_0592  sensor kinase CusS [KO:K07644] [EC:2.7.13.3]
CDCO157_0593  DNA-binding transcriptional activator CusR [KO:K07665]
CDCO157_0594  copper/silver efflux system outer membrane protein CusC [KO:K07796]
CDCO157_0595  periplasmic copper-binding protein [KO:K07810]
CDCO157_0596  copper/silver efflux system membrane fusion protein CusB [KO:K07798]
CDCO157_0597  putative inner membrane component for iron transport [KO:K07787]
CDCO157_3650A  sensor histidine kinase QseC [KO:K07645] [EC:2.7.13.3]
CDCO157_3650  DNA-binding transcriptional regulator QseB [KO:K07666]
CDCO157_2437  transcriptional activator FlhD [KO:K02403]
CDCO157_2436  transcriptional activator FlhC [KO:K02402]
CDCO157_2460  flagellin [KO:K02406]
CDCO157_2459  fliA; flagellar biosynthesis sigma factor [KO:K02405]
CDCO157_2435  flagellar motor protein MotA [KO:K02556]
CDCO157_0703  sensor protein KdpD [KO:K07646] [EC:2.7.13.3]
CDCO157_0702  DNA-binding transcriptional activator KdpE [KO:K07667]
CDCO157_0706  potassium-transporting ATPase subunit A [KO:K01546]
CDCO157_0705  potassium-transporting ATPase subunit B [KO:K01547] [EC:7.2.2.6]
CDCO157_0704  potassium-transporting ATPase subunit C [KO:K01548]
CDCO157_0707  KdpF protein of high-affinity potassium transport system [KO:K01545]
CDCO157_1113  hybrid sensory histidine kinase TorS [KO:K07647] [EC:2.7.13.3]
CDCO157_1115  DNA-binding transcriptional regulator TorR [KO:K07772]
CDCO157_1116  trimethylamine N-oxide reductase cytochrome c-type subunit [KO:K03532]
CDCO157_1117  trimethylamine N-oxide reductase subunit [KO:K07811] [EC:1.7.2.3]
CDCO157_1118  torD; chaperone protein TorD [KO:K03533]
CDCO157_3830  aerobic respiration control sensor protein ArcB [KO:K07648] [EC:2.7.13.3]
CDCO157_5043  two-component response regulator [KO:K07773]
CDCO157_4373  dnaA; chromosomal replication initiation protein [KO:K02313]
CDCO157_1936  D-alanyl-D-alanine dipeptidase [KO:K08641] [EC:3.4.13.22]
CDCO157_0607  outer membrane receptor FepA [KO:K19611]
CDCO157_0645  putative sensor-type protein [KO:K07700] [EC:2.7.13.3]
CDCO157_0646  dpiA; two-component response regulator DpiA [KO:K07702]
CDCO157_0644  citrate lyase synthetase (citrate (pro-3S)-lyase ligase) [KO:K01910] [EC:6.2.1.22]
CDCO157_0643  citrate lyase subunit gamma [KO:K01646]
CDCO157_0642  citrate lyase beta chain [KO:K01644] [EC:4.1.3.34]
CDCO157_0641  citrate lyase alpha chain [KO:K01643] [EC:2.8.3.10]
CDCO157_0640  citX; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase [KO:K05964] [EC:2.7.7.61]
CDCO157_0639  citG; triphosphoribosyl-dephospho-CoA synthase [KO:K05966] [EC:2.4.2.52]
CDCO157_0638  hypothetical protein [KO:K09477]
CDCO157_4792  sensory histidine kinase DcuS [KO:K07701] [EC:2.7.13.3]
CDCO157_4791  DNA-binding transcriptional activator DcuR [KO:K07703]
CDCO157_4790  anaerobic C4-dicarboxylate transporter [KO:K07792]
CDCO157_1927  malate dehydrogenase [KO:K00027] [EC:1.1.1.38]
CDCO157_1655  nitrate/nitrite sensor protein NarX [KO:K07673] [EC:2.7.13.3]
CDCO157_1654  transcriptional regulator NarL [KO:K07684]
CDCO157_3096  nitrate/nitrite sensor protein NarQ [KO:K07674] [EC:2.7.13.3]
CDCO157_2845  transcriptional regulator NarP [KO:K07685]
CDCO157_1915  cryptic nitrate reductase 2 alpha subunit [KO:K00370] [EC:1.7.5.1 1.7.99.-]
CDCO157_1658  nitrate reductase 1 alpha subunit [KO:K00370] [EC:1.7.5.1 1.7.99.-]
CDCO157_1914  cryptic nitrate reductase 2 beta subunit [KO:K00371] [EC:1.7.5.1 1.7.99.-]
CDCO157_1659  nitrate reductase 1 beta subunit [KO:K00371] [EC:1.7.5.1 1.7.99.-]
CDCO157_1912  cryptic nitrate reductase 2 gamma subunit [KO:K00374] [EC:1.7.5.1 1.7.99.-]
CDCO157_1661  nitrate reductase 1 gamma subunit [KO:K00374] [EC:1.7.5.1 1.7.99.-]
CDCO157_1913  cryptic nitrate reductase 2 delta subunit [KO:K00373]
CDCO157_1660  nitrate reductase 1 delta subunit [KO:K00373]
CDCO157_1923  nitrate-inducible formate dehydrogenase-N iron-sulfur beta subunit [KO:K08349]
CDCO157_1924  formate dehydrogenase-N subunit gamma [KO:K08350]
CDCO157_4821  fumarate reductase flavoprotein subunit [KO:K00244] [EC:1.3.5.1]
CDCO157_4820  fumarate reductase iron-sulfur subunit [KO:K00245] [EC:1.3.5.1]
CDCO157_4819  fumarate reductase subunit C [KO:K00246]
CDCO157_4818  fumarate reductase subunit D [KO:K00247]
CDCO157_0404  putative regulatory protein [KO:K07783]
CDCO157_4339  regulatory protein UhpC [KO:K07783]
CDCO157_4340  sensory histidine kinase UhpB [KO:K07675] [EC:2.7.13.3]
CDCO157_4341  DNA-binding transcriptional activator UhpA [KO:K07686]
CDCO157_4338  uhpT; sugar phosphate antiporter [KO:K07784]
CDCO157_0405  putative sensor histidine protein kinase [KO:K20263] [EC:2.7.13.3]
CDCO157_0406  putative transcription regulator [KO:K20264]
CDCO157_4323  Ler [KO:K20552]
CDCO157_0197  rcsF; outer membrane lipoprotein [KO:K06080]
CDCO157_2871  hybrid sensory kinase in two-component regulatory system with RcsB and YojN [KO:K07677] [EC:2.7.13.3]
CDCO157_2869  phosphotransfer intermediate protein in two-component regulatory system with RcsBC [KO:K07676] [EC:2.7.13.3]
CDCO157_2484  transcriptional regulator for ctr capsule biosynthesis [KO:K07781]
CDCO157_2870  transcriptional regulator RcsB [KO:K07687]
CDCO157_3401  hybrid sensory histidine kinase BarA [KO:K07678] [EC:2.7.13.3]
CDCO157_2452  response regulator [KO:K07689]
CDCO157_2454  DNA-binding transcriptional activator SdiA [KO:K07782]
CDCO157_3314  carbon storage regulator [KO:K03563]
CDCO157_3013  hybrid sensory histidine kinase in two-component regulatory system with EvgA [KO:K07679] [EC:2.7.13.3]
CDCO157_3012  DNA-binding transcriptional activator EvgA [KO:K07690]
CDCO157_3011  multidrug resistance protein K [KO:K07797]
CDCO157_3010  multidrug resistance protein Y [KO:K07786]
CDCO157_1947  hypothetical protein [KO:K23236]
CDCO157_0580  transcriptional regulator FimZ [KO:K07688]
CDCO157_4817  ampC; beta-lactamase [KO:K01467] [EC:3.5.2.6]
CDCO157_4960  FimC [KO:K07346]
CDCO157_1953  putative fimbrial chaperone protein precursor [KO:K07346]
CDCO157_4166  putative fimbrial chaperone protein precursor [KO:K07346]
CDCO157_0998  putative chaperone [KO:K07346]
CDCO157_1225  putative chaperone protein [KO:K07346]
CDCO157_0020  putative outer membrane usher protein precursor [KO:K07347]
CDCO157_0141  putative outer membrane usher protein [KO:K07347]
CDCO157_3763  putative outer membrane protein [KO:K07347]
CDCO157_1952  putative outer membrane protein [KO:K07347]
CDCO157_1224  putative outer membrane usher protein [KO:K07347]
CDCO157_4403  putative outer membrane usher protein precursor [KO:K07347]
CDCO157_2692  putative outer membrane protein [KO:K07347]
CDCO157_4961  FimD [KO:K07347]
CDCO157_0167  PII uridylyl-transferase [KO:K00990] [EC:2.7.7.59]
CDCO157_3187  nitrogen regulatory protein P-II 1 [KO:K04751]
CDCO157_4530  glnL; nitrogen regulation protein NR(II) [KO:K07708] [EC:2.7.13.3]
CDCO157_4529  glnG; nitrogen regulation protein NR(I) [KO:K07712]
CDCO157_4531  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CDCO157_4667  sensor protein ZraS [KO:K07709] [EC:2.7.13.3]
CDCO157_4668  transcriptional regulatory protein ZraR [KO:K07713]
CDCO157_4666  zraP; zinc resistance protein [KO:K07803]
CDCO157_3456  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CDCO157_4146  C4-dicarboxylate transporter DctA [KO:K11103]
CDCO157_3822  RNA polymerase factor sigma-54 [KO:K03092]
CDCO157_3190  putative 2-component sensor protein [KO:K07711] [EC:2.7.13.3]
CDCO157_3188  putative 2-component transcriptional regulator [KO:K07715]
CDCO157_1093  hydrogenase-1 small subunit [KO:K06282] [EC:1.12.99.6]
CDCO157_3625  hydrogenase 2 small subunit [KO:K06282] [EC:1.12.99.6]
CDCO157_1094  hydrogenase 1 large subunit [KO:K06281] [EC:1.12.99.6]
CDCO157_3622  hydrogenase 2 large subunit [KO:K06281] [EC:1.12.99.6]
CDCO157_1095  hydrogenase 1 b-type cytochrome subunit [KO:K03620]
CDCO157_2429  chemotaxis methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
CDCO157_5001  methyl-accepting chemotaxis protein I [KO:K05874]
CDCO157_2431  methyl-accepting chemotaxis protein II [KO:K05875]
CDCO157_1871  methyl-accepting chemotaxis protein III [KO:K05876]
CDCO157_2430  methyl-accepting protein IV [KO:K05877]
CDCO157_3695  aerotaxis sensor receptor [KO:K03776]
CDCO157_2432  purine-binding chemotaxis protein [KO:K03408]
CDCO157_2433  chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
CDCO157_2427  chemotaxis regulatory protein CheY [KO:K03413]
CDCO157_2428  chemotaxis-specific methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
CDCO157_0676  ATP-binding protein of glutamate/aspartate transport system [KO:K10004] [EC:7.4.2.1]
CDCO157_0677  glutamate/aspartate transport system permease [KO:K10002]
CDCO157_0678  glutamate/aspartate transport system permease [KO:K10003]
CDCO157_0679  glutamate and aspartate transporter subunit [KO:K10001]
CDCO157_3949  cAMP-regulatory protein [KO:K10914]
CDCO157_0526  glutaminase [KO:K01425] [EC:3.5.1.2]
CDCO157_1971  glutaminase [KO:K01425] [EC:3.5.1.2]
CDCO157_1099  putative third cytochrome oxidase subunit I [KO:K00425] [EC:7.1.1.7]
CDCO157_0747  cytochrome d terminal oxidase polypeptide subunit I [KO:K00425] [EC:7.1.1.7]
CDCO157_1100  putative third cytochrome oxidase subunit II [KO:K00426] [EC:7.1.1.7]
CDCO157_0748  cytochrome d terminal oxidase polypeptide subunit II [KO:K00426] [EC:7.1.1.7]
CDCO157_0749  hypothetical protein [KO:K00424] [EC:7.1.1.7]
CDCO157_3664  tolC; outer membrane channel protein [KO:K12340]
CDCO157_1104  hypothetical protein [KO:K01991]
CDCO157_2647  putative polysaccharide export protein [KO:K01991]
CDCO157_2646  tyrosine phosphatase [KO:K25307] [EC:3.1.3.48]
CDCO157_1103  etp; phosphotyrosine-protein phosphatase [KO:K25307] [EC:3.1.3.48]
CDCO157_2645  tyrosine kinase [KO:K16692] [EC:2.7.10.3]
CDCO157_1102  cryptic autophosphorylating protein tyrosine kinase Etk [KO:K16692] [EC:2.7.10.3]
CDCO157_4456  UDP-N-acetylglucosamine 2-epimerase [KO:K01791] [EC:5.1.3.14]
CDCO157_4457  wecC; UDP-N-acetyl-D-mannosamine dehydrogenase [KO:K02472] [EC:1.1.1.336]
CDCO157_0780  putative pectinesterase [KO:K01051] [EC:3.1.1.11]
CDCO157_1384  anti-sigma28 factor FlgM [KO:K02398]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00034  Manganese
C00036  Oxaloacetate
C00038  Zinc cation
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00070  Copper
C00088  Nitrite
C00092  D-Glucose 6-phosphate
C00122  Fumarate
C00149  (S)-Malate
C00158  Citrate
C00164  Acetoacetate
C00237  CO
C00238  Potassium cation
C00244  Nitrate
C00282  Hydrogen
C00291  Nickel
C00305  Magnesium cation
C00399  Ubiquinone
C00533  Nitric oxide
C00547  L-Noradrenaline
C00697  Nitrogen
C00788  L-Adrenaline
C00828  Menaquinone
C01019  L-Fucose
C01104  Trimethylamine N-oxide
C01667  Bacitracin
C02084  Tetrathionate
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05818  2-Demethylmenaquinone
C06230  Fe-enterobactin
C06689  Vancomycin
C06696  Lead
C11612  Polymyxin B
C11842  N-(3-(S)-Hydroxybutyryl)homoserine lactone
C11849  3-Hydroxy-palmitic acid methyl ester
C12008  Ramoplanin A2
C13768  Colistin sulfate
C14819  Fe3+
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C16665  12-Methyltetradecanoic acid
C18206  cis-11-Methyl-2-dodecenoic acid
C21220  AIP-1
C21221  CSP
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21245  AgrD1 peptide
D07746  Colistin (INN)
D08401  Polymyxin B (INN)
Reference
PMID:15522865
  Authors
Yamamoto K, Hirao K, Oshima T, Aiba H, Utsumi R, Ishihama A.
  Title
Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli.
  Journal
J Biol Chem 280:1448-56 (2005)
DOI:10.1074/jbc.M410104200
Reference
PMID:16030210
  Authors
Abdel-Fattah WR, Chen Y, Eldakak A, Hulett FM.
  Title
Bacillus subtilis phosphorylated PhoP: direct activation of the E(sigma)A- and repression of the E(sigma)E-responsive phoB-PS+V promoters during pho response.
  Journal
J Bacteriol 187:5166-78 (2005)
DOI:10.1128/JB.187.15.5166-5178.2005
Reference
PMID:15813739
  Authors
Navarre WW, Halsey TA, Walthers D, Frye J, McClelland M, Potter JL, Kenney LJ, Gunn JS, Fang FC, Libby SJ.
  Title
Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ.
  Journal
Mol Microbiol 56:492-508 (2005)
DOI:10.1111/j.1365-2958.2005.04553.x
Reference
PMID:11973328
  Authors
Cai SJ, Inouye M.
  Title
EnvZ-OmpR interaction and osmoregulation in Escherichia coli.
  Journal
J Biol Chem 277:24155-61 (2002)
DOI:10.1074/jbc.M110715200
Reference
PMID:16077119
  Authors
Batchelor E, Walthers D, Kenney LJ, Goulian M.
  Title
The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC.
  Journal
J Bacteriol 187:5723-31 (2005)
DOI:10.1128/JB.187.16.5723-5731.2005
Reference
PMID:12107133
  Authors
Nagakubo S, Nishino K, Hirata T, Yamaguchi A.
  Title
The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC.
  Journal
J Bacteriol 184:4161-7 (2002)
DOI:10.1128/JB.184.15.4161-4167.2002
Reference
PMID:15322361
  Authors
Hagiwara D, Yamashino T, Mizuno T.
  Title
A Genome-wide view of the Escherichia coli BasS-BasR two-component system implicated in iron-responses.
  Journal
Biosci Biotechnol Biochem 68:1758-67 (2004)
DOI:10.1271/bbb.68.1758
Reference
PMID:11004187
  Authors
Munson GP, Lam DL, Outten FW, O'Halloran TV.
  Title
Identification of a copper-responsive two-component system on the chromosome of Escherichia coli K-12.
  Journal
J Bacteriol 182:5864-71 (2000)
DOI:10.1128/JB.182.20.5864-5871.2000
Reference
PMID:11929534
  Authors
Sperandio V, Torres AG, Kaper JB.
  Title
Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli.
  Journal
Mol Microbiol 43:809-21 (2002)
DOI:10.1046/j.1365-2958.2002.02803.x
Reference
PMID:14604015
  Authors
Epstein W.
  Title
The roles and regulation of potassium in bacteria.
  Journal
Prog Nucleic Acid Res Mol Biol 75:293-320 (2003)
DOI:10.1016/S0079-6603(03)75008-9
Reference
PMID:10648521
  Authors
Ansaldi M, Simon G, Lepelletier M, Mejean V.
  Title
The TorR high-affinity binding site plays a key role in both torR autoregulation and torCAD operon expression in Escherichia coli.
  Journal
J Bacteriol 182:961-6 (2000)
DOI:10.1128/JB.182.4.961-966.2000
Reference
PMID:15326287
  Authors
Malpica R, Franco B, Rodriguez C, Kwon O, Georgellis D.
  Title
Identification of a quinone-sensitive redox switch in the ArcB sensor kinase.
  Journal
Proc Natl Acad Sci U S A 101:13318-23 (2004)
DOI:10.1073/pnas.0403064101
Reference
PMID:2666399
  Authors
Widenhorn KA, Somers JM, Kay WW.
  Title
Genetic regulation of the tricarboxylate transport operon (tctI) of Salmonella typhimurium.
  Journal
J Bacteriol 171:4436-41 (1989)
DOI:10.1128/JB.171.8.4436-4441.1989
Reference
PMID:11555295
  Authors
Hyyrylainen HL, Bolhuis A, Darmon E, Muukkonen L, Koski P, Vitikainen M, Sarvas M, Pragai Z, Bron S, van Dijl JM, Kontinen VP.
  Title
A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress.
  Journal
Mol Microbiol 41:1159-72 (2001)
DOI:10.1046/j.1365-2958.2001.02576.x
Reference
PMID:10972837
  Authors
Zhang X, Hulett FM.
  Title
ResD signal transduction regulator of aerobic respiration in Bacillus subtilis: ctaA promoter regulation.
  Journal
Mol Microbiol 37:1208-19 (2000)
DOI:10.1046/j.1365-2958.2000.02076.x
Reference
PMID:15937169
  Authors
Senadheera MD, Guggenheim B, Spatafora GA, Huang YC, Choi J, Hung DC, Treglown JS, Goodman SD, Ellen RP, Cvitkovitch DG.
  Title
A VicRK signal transduction system in Streptococcus mutans affects gtfBCD, gbpB, and ftf expression, biofilm formation, and genetic competence development.
  Journal
J Bacteriol 187:4064-76 (2005)
DOI:10.1128/JB.187.12.4064-4076.2005
Reference
PMID:15601704
  Authors
He H, Zahrt TC.
  Title
Identification and characterization of a regulatory sequence recognized by Mycobacterium tuberculosis persistence regulator MprA.
  Journal
J Bacteriol 187:202-12 (2005)
DOI:10.1128/JB.187.1.202-212.2005
Reference
PMID:17448786
  Authors
Hutchings MI
  Title
Unusual two-component signal transduction pathways in the actinobacteria.
  Journal
Adv Appl Microbiol 61:1-26 (2007)
DOI:10.1016/S0065-2164(06)61001-0
Reference
PMID:19308662
  Authors
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  Title
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Related
pathway
elx00190  Oxidative phosphorylation
elx00550  Peptidoglycan biosynthesis
elx00910  Nitrogen metabolism
elx02030  Bacterial chemotaxis
elx02040  Flagellar assembly
elx03070  Bacterial secretion system
KO pathway
ko02020   
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