Entry
Name
ABC transporters - Enterobacter sp. T2
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Enterobacter sp. T2 [GN:
enz ]
Gene
G0034_03535 thiP; thiamine/thiamine pyrophosphate ABC transporter permease ThiP [KO:K02063 ]
G0034_08545 potD; spermidine/putrescine ABC transporter substrate-binding protein PotD [KO:K11069 ]
G0034_07095 potF; spermidine/putrescine ABC transporter substrate-binding protein PotF [KO:K11073 ]
G0034_17785 proX; glycine betaine/L-proline ABC transporter substrate-binding protein ProX [KO:K02002 ]
G0034_17780 proW; glycine betaine/L-proline ABC transporter permease ProW [KO:K02001 ]
G0034_09830 osmX; osmoprotectant ABC transporter substrate-binding protein OsmX [KO:K05845 ]
G0034_01195 malE; maltose/maltodextrin ABC transporter substrate-binding protein MalE [KO:K10108 ]
G0034_22140 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10111 ] [EC:7.5.2.-]
G0034_01200 malK; maltose/maltodextrin ABC transporter ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
G0034_20305 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
G0034_20310 mlaE; lipid asymmetry maintenance ABC transporter permease subunit MlaE [KO:K02066 ]
G0034_02190 ytfQ; galactofuranose ABC transporter substrate-binding protein YtfQ [KO:K23508 ]
G0034_15655 mglB; galactose/glucose ABC transporter substrate-binding protein MglB [KO:K10540 ]
G0034_15645 mglC; galactose/methyl galactoside ABC transporter permease MglC [KO:K10541 ]
G0034_01310 ugpB; sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB [KO:K05813 ]
G0034_23125 pstS; phosphate ABC transporter substrate-binding protein PstS [KO:K02040 ]
G0034_21720 phnD; phosphate/phosphite/phosphonate ABC transporter substrate-binding protein [KO:K02044 ]
G0034_16230 argT; lysine/arginine/ornithine ABC transporter substrate-binding protein ArgT [KO:K10013 ]
G0034_16225 hisJ; histidine ABC transporter substrate-binding protein HisJ [KO:K10014 ]
G0034_06830 glnH; glutamine ABC transporter substrate-binding protein GlnH [KO:K10036 ]
G0034_13885 branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
G0034_01275 branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
G0034_01285 livk; high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK [KO:K01999 ]
G0034_01290 livH; high-affinity branched-chain amino acid ABC transporter permease LivH [KO:K01997 ]
G0034_13895 livM; high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998 ]
G0034_01295 high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998 ]
G0034_01300 livG; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG [KO:K01995 ]
G0034_01305 livF; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF [KO:K01996 ]
G0034_04240 metQ; methionine ABC transporter substrate-binding lipoprotein MetQ [KO:K02073 ]
G0034_12745 oppA; oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
G0034_12725 oppF; murein tripeptide/oligopeptide ABC transporter ATP binding protein OppF [KO:K10823 ]
G0034_06975 gsiB; glutathione ABC transporter substrate-binding protein GsiB [KO:K13889 ]
G0034_05835 fepB; Fe2+-enterobactin ABC transporter substrate-binding protein [KO:K23185 ]
G0034_04020 fhuD; Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD [KO:K23227 ]
G0034_05775 sitB; iron/manganese ABC transporter ATP-binding protein SitB [KO:K11607 ]
G0034_19805 lsrB; autoinducer 2 ABC transporter substrate-binding protein LsrB [KO:K10555 ]
G0034_08510 lolC; lipoprotein-releasing ABC transporter permease subunit LolC [KO:K09808 ]
G0034_08520 lolE; lipoprotein-releasing ABC transporter permease subunit LolE [KO:K09808 ]
G0034_08515 lolD; lipoprotein-releasing ABC transporter ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
G0034_05000 SmdA family multidrug ABC transporter permease/ATP-binding protein [KO:K18889 ]
G0034_05005 SmdB family multidrug efflux ABC transporter permease/ATP-binding protein [KO:K18890 ]
G0034_07360 cydC; cysteine/glutathione ABC transporter ATP-binding protein/permease CydC [KO:K16012 ]
G0034_07365 cydD; cysteine/glutathione ABC transporter permease/ATP-binding protein CydD [KO:K16013 ]
G0034_07325 macB; macrolide ABC transporter ATP-binding protein/permease MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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