Entry
Name
ABC transporters - Klebsiella michiganensis E718
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Klebsiella michiganensis E718 [GN:
koe ]
Gene
A225_3402 ABC-type nitrate/sulfonate/bicarbonate transport system protein [KO:K15553 ]
A225_3401 ABC-type nitrate/sulfonate/bicarbonate transport system protein [KO:K15553 ]
A225_2617 ABC-type nitrate/sulfonate/bicarbonate transport system protein [KO:K15553 ]
A225_1143 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter [KO:K15555 ] [EC:7.6.2.14 ]
A225_2065 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter [KO:K15555 ] [EC:7.6.2.14 ]
A225_3399 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter [KO:K15555 ] [EC:7.6.2.14 ]
A225_1787 Putative molybdenum transport ATP-binding protein modF [KO:K05776 ]
A225_2352 Spermidine Putrescine ABC transporter permease component PotB [KO:K11071 ]
A225_1980 Putrescine ABC transporter putrescine-binding protein PotF [KO:K11073 ]
A225_5746 2-aminoethylphosphonate ABC transporter periplasmic binding component [KO:K11081 ]
A225_5743 2-aminoethylphosphonate ABC transporter permease protein II [KO:K11082 ]
A225_5744 2-aminoethylphosphonate ABC transporter permease protein I [KO:K11083 ]
A225_5745 2-aminoethylphosphonate ABC transporter ATP-binding protein [KO:K11084 ]
A225_4536 L-proline glycine betaine binding ABC transporter protein ProX [KO:K02002 ]
A225_4535 L-proline glycine betaine ABC transport system permease protein ProW [KO:K02001 ]
A225_1111 L-proline glycine betaine binding ABC transporter protein ProX [KO:K05845 ]
A225_1112 Glycine betaine ABC transport system permease protein [KO:K05846 ]
A225_1113 L-proline glycine betaine ABC transport system permease protein ProW [KO:K05846 ]
A225_3567 binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
A225_3568 Glycine betaine ABC transport system permease protein [KO:K05846 ]
A225_4017 Osmoprotectant ABC transporter inner membrane protein YehW [KO:K05846 ]
A225_0310 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
A225_1309 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
A225_1716 Xylose ABC transporter periplasmic xylose-binding protein XylF [KO:K10439 ]
A225_3700 L-arabinose-binding periplasmic protein precursor AraF [KO:K10537 ]
A225_0560 putative SN-glycerol-3-phosphate transport system permease [KO:K05815 ]
A225_1150 Phosphonate ABC transporter phosphate-binding periplasmic component [KO:K02044 ]
A225_4209 Lysine-arginine-ornithine-binding periplasmic protein precursor [KO:K10013 ]
A225_1679 Glutamate Aspartate periplasmic binding protein precursor GltI [KO:K10001 ]
A225_1677 Glutamate Aspartate transport system permease protein GltK [KO:K10002 ]
A225_1678 Glutamate Aspartate transport system permease protein GltJ [KO:K10003 ]
A225_1169 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
A225_5434 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
A225_1168 Branched-chain amino acid transport system permease protein LivM [KO:K01998 ]
A225_5433 Branched-chain amino acid transport system permease protein LivM [KO:K01998 ]
A225_1167 Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 ]
A225_5432 Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 ]
A225_1166 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
A225_5431 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
A225_2427 Iron(III) dicitrate transport system periplasmic iron-binding protein FecB [KO:K23181 ]
A225_2425 Iron(III) dicitrate transport system permease protein FecD [KO:K23182 ]
A225_2426 Iron(III) dicitrate transport system permease protein FecC [KO:K23183 ]
A225_1603 Ferric enterobactin transport system permease protein FepD [KO:K23186 ]
A225_1602 Ferric enterobactin transport system permease protein FepG [KO:K23187 ]
A225_4737 Additional substrate-specific component CbiN of cobalt ECF transporter [KO:K02009 ]
A225_4738 Substrate-specific component CbiM of cobalt ECF transporter [KO:K02007 ]
A225_4736 Transmembrane component CbiQ of energizing module of cobalt ECF transporter [KO:K02008 ]
A225_4735 ATPase component CbiO of energizing module of cobalt ECF transporter [KO:K02006 ]
A225_4961 Transmembrane component of energizing module of queuosine-regulated ECF transporter [KO:K16785 ]
A225_4962 ATPase component of energizing module of queuosine-regulated ECF transporter [KO:K16786 ] [EC:7.-.-.-]
A225_4963 ATPase component of energizing module of queuosine-regulated ECF transporter [KO:K16787 ] [EC:7.-.-.-]
A225_2334 Lipoprotein releasing system transmembrane protein LolC [KO:K09808 ]
A225_2336 Lipoprotein releasing system transmembrane protein LolE [KO:K09808 ]
A225_2335 Lipoprotein releasing system ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
A225_2990 Putative ABC iron siderophore transporter [KO:K14698 ] [EC:7.-.-.-]
A225_2008 Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
A225_4633 Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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