KEGG   PATHWAY: maad02024
Entry
maad02024                   Pathway                                
Name
Quorum sensing - Martelella sp. AD-3
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
maad02024  Quorum sensing
maad02024

Other DBs
GO: 0009372
Organism
Martelella sp. AD-3 [GN:maad]
Gene
AZF01_09965  RNA chaperone Hfq [KO:K03666]
AZF01_03060  hypothetical protein [KO:K18304]
AZF01_11260  phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
AZF01_10800  phenazine biosynthesis protein PhzF [KO:K06998] [EC:5.3.3.17]
AZF01_22435  histidine kinase [KO:K07645] [EC:2.7.13.3]
AZF01_22440  two-component system response regulator [KO:K07666]
AZF01_20205  hypothetical protein [KO:K07782]
AZF01_20795  glutamate decarboxylase [KO:K01580] [EC:4.1.1.15]
AZF01_03975  hypothetical protein [KO:K18098]
AZF01_18430  conjugal transfer protein TrbB [KO:K20527] [EC:7.4.2.8]
AZF01_18425  conjugal transfer protein TrbC [KO:K20528]
AZF01_18420  conjugal transfer protein [KO:K20529]
AZF01_18415  conjugal transfer protein TrbE [KO:K20530] [EC:7.4.2.8]
AZF01_18410  conjugal transfer protein TrbJ [KO:K20266]
AZF01_18400  conjugal transfer protein TrbL [KO:K07344]
AZF01_18395  conjugal transfer protein TrbF [KO:K20531]
AZF01_18390  conjugal transfer protein TrbG [KO:K20532]
AZF01_18385  conjugal transfer protein TraI [KO:K20533]
AZF01_03770  potassium transporter Trk [KO:K02055]
AZF01_04410  ABC transporter substrate-binding protein [KO:K02055]
AZF01_04465  hypothetical protein [KO:K02055]
AZF01_08920  spermidine/putrescine ABC transporter substrate-binding protein [KO:K02055]
AZF01_16485  ABC transporter substrate-binding protein [KO:K02055]
AZF01_17235  ABC transporter substrate-binding protein [KO:K02055]
AZF01_19125  spermidine/putrescine ABC transporter [KO:K02055]
AZF01_03775  spermidine/putrescine ABC transporter permease [KO:K02053]
AZF01_04475  hypothetical protein [KO:K02053]
AZF01_08930  polyamine ABC transporter permease [KO:K02053]
AZF01_16475  ABC transporter permease [KO:K02053]
AZF01_17225  spermidine/putrescine ABC transporter ATP-binding protein [KO:K02053]
AZF01_19135  spermidine/putrescine ABC transporter ATP-binding protein [KO:K02053]
AZF01_04415  ABC transporter permease [KO:K02053 K02054]
AZF01_03780  spermidine/putrescine ABC transporter permease [KO:K02054]
AZF01_04470  hypothetical protein [KO:K02054]
AZF01_08925  polyamine ABC transporter permease [KO:K02054]
AZF01_16480  ABC transporter permease [KO:K02054]
AZF01_17230  spermidine/putrescine ABC transporter permease [KO:K02054]
AZF01_19130  spermidine/putrescine ABC transporter permease [KO:K02054]
AZF01_04405  Fe3+/spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
AZF01_08915  spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
AZF01_17220  ABC transporter ATP-binding protein [KO:K02052]
AZF01_19140  Fe3+/spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
AZF01_16470  Fe3+/spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
AZF01_03785  ABC transporter ATP-binding protein [KO:K02052]
AZF01_07190  hypothetical protein [KO:K01999]
AZF01_22020  ABC transporter permease [KO:K01999]
AZF01_11710  amino acid ABC transporter [KO:K01999]
AZF01_20720  ABC transporter substrate-binding protein [KO:K01999]
AZF01_08320  ABC transporter substrate-binding protein [KO:K01999]
AZF01_21455  ABC transporter substrate-binding protein [KO:K01999]
AZF01_21720  ABC transporter substrate-binding protein [KO:K01999]
AZF01_21825  ABC transporter substrate-binding protein [KO:K01999]
AZF01_12195  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
AZF01_07195  ABC transporter permease [KO:K01997]
AZF01_22035  ABC transporter permease [KO:K01997]
AZF01_20725  ABC transporter permease [KO:K01997]
AZF01_08335  ABC transporter permease [KO:K01997]
AZF01_21470  ABC transporter permease [KO:K01997]
AZF01_21770  ABC transporter permease [KO:K01997]
AZF01_21810  ABC transporter permease [KO:K01997]
AZF01_12200  ABC transporter permease [KO:K01997]
AZF01_07200  hypothetical protein [KO:K01998]
AZF01_20730  branched-chain amino acid ABC transporter permease [KO:K01998]
AZF01_08340  ABC transporter permease [KO:K01998]
AZF01_21475  hypothetical protein [KO:K01998]
AZF01_21765  ABC transporter permease [KO:K01998]
AZF01_21805  ABC transporter permease [KO:K01998]
AZF01_22040  ABC transporter permease [KO:K01998]
AZF01_07205  ABC transporter ATP-binding protein [KO:K01995]
AZF01_22025  ABC transporter ATP-binding protein [KO:K01995]
AZF01_20735  livG; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG [KO:K01995]
AZF01_08325  ABC transporter ATP-binding protein [KO:K01995]
AZF01_21460  ABC transporter ATP-binding protein [KO:K01995]
AZF01_12210  ABC transporter ATP-binding protein [KO:K01995]
AZF01_21780  ABC transporter ATP-binding protein [KO:K01995]
AZF01_21820  ABC transporter ATP-binding protein [KO:K01995]
AZF01_07210  livF; ABC transporter ATP-binding protein [KO:K01996]
AZF01_20740  ABC transporter ATP-binding protein [KO:K01996]
AZF01_12215  ABC transporter ATP-binding protein [KO:K01996]
AZF01_08330  ABC transporter ATP-binding protein [KO:K01996]
AZF01_21465  ABC transporter ATP-binding protein [KO:K01996]
AZF01_21775  ABC transporter ATP-binding protein [KO:K01996]
AZF01_21815  ABC transporter ATP-binding protein [KO:K01996]
AZF01_22030  ABC transporter ATP-binding protein [KO:K01996]
AZF01_22140  hypothetical protein [KO:K20539]
AZF01_22125  MBL fold metallo-hydrolase [KO:K13075] [EC:3.1.1.81]
AZF01_14400  hypothetical protein [KO:K20276]
AZF01_05980  Fur family transcriptional regulator [KO:K09823]
AZF01_18945  GTP cyclohydrolase [KO:K01497] [EC:3.5.4.25]
AZF01_00915  bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase [KO:K11752] [EC:3.5.4.26 1.1.1.193]
AZF01_19660  hypothetical protein [KO:K09936]
AZF01_19665  hypothetical protein [KO:K09936]
AZF01_07100  hypothetical protein [KO:K02035]
AZF01_07115  hypothetical protein [KO:K02035]
AZF01_15160  ABC transporter substrate-binding protein [KO:K02035]
AZF01_07845  ABC transporter substrate-binding protein [KO:K02035]
AZF01_12385  peptide ABC transporter substrate-binding protein [KO:K02035]
AZF01_21235  peptide ABC transporter substrate-binding protein [KO:K02035]
AZF01_21310  peptide ABC transporter [KO:K02035]
AZF01_13080  hypothetical protein [KO:K02035]
AZF01_14045  peptide ABC transporter substrate-binding protein [KO:K02035]
AZF01_19170  peptide ABC transporter [KO:K02035]
AZF01_07350  peptide ABC transporter substrate-binding protein [KO:K02035]
AZF01_02005  peptide ABC transporter substrate-binding protein [KO:K02035]
AZF01_10860  ABC transporter substrate-binding protein [KO:K02035]
AZF01_09820  bicyclomycin resistance protein [KO:K02035]
AZF01_21570  peptide ABC transporter substrate-binding protein [KO:K02035]
AZF01_03120  nickel ABC transporter substrate-binding protein [KO:K02035]
AZF01_14505  ABC transporter substrate-binding protein [KO:K02035]
AZF01_09455  peptide ABC transporter substrate-binding protein [KO:K02035]
AZF01_15165  peptide ABC transporter [KO:K02033]
AZF01_07850  glutathione ABC transporter permease [KO:K02033]
AZF01_12405  peptide ABC transporter [KO:K02033]
AZF01_21230  ABC transporter permease [KO:K02033]
AZF01_21305  peptide ABC transporter [KO:K02033]
AZF01_13075  peptide ABC transporter [KO:K02033]
AZF01_09460  ABC transporter permease [KO:K02033]
AZF01_14050  glutathione ABC transporter permease [KO:K02033]
AZF01_19175  ABC transporter permease [KO:K02033]
AZF01_07370  peptide ABC transporter permease [KO:K02033]
AZF01_02000  ABC transporter permease [KO:K02033]
AZF01_10850  ABC transporter permease [KO:K02033]
AZF01_21565  ABC transporter permease [KO:K02033]
AZF01_03125  ABC transporter permease [KO:K02033]
AZF01_14515  ABC transporter permease [KO:K02033]
AZF01_07105  peptide ABC transporter permease [KO:K02033]
AZF01_07110  peptide ABC transporter permease [KO:K02034]
AZF01_15170  peptide ABC transporter permease [KO:K02034]
AZF01_07855  diguanylate cyclase [KO:K02034]
AZF01_12400  peptide ABC transporter permease [KO:K02034]
AZF01_21225  ABC transporter permease [KO:K02034]
AZF01_21300  peptide ABC transporter permease [KO:K02034]
AZF01_09465  peptide ABC transporter permease [KO:K02034]
AZF01_19180  peptide ABC transporter permease [KO:K02034]
AZF01_07365  peptide ABC transporter permease [KO:K02034]
AZF01_01995  peptide ABC transporter permease [KO:K02034]
AZF01_10845  peptide ABC transporter permease [KO:K02034]
AZF01_21560  ABC transporter permease [KO:K02034]
AZF01_03130  peptide ABC transporter permease [KO:K02034]
AZF01_14520  peptide ABC transporter permease [KO:K02034]
AZF01_14055  peptide ABC transporter permease [KO:K02031 K02034]
AZF01_07090  glutathione ABC transporter ATP-binding protein [KO:K02031 K02032]
AZF01_12395  peptide ABC transporter ATP-binding protein [KO:K02031 K02032]
AZF01_21220  ABC transporter ATP-binding protein [KO:K02031 K02032]
AZF01_10855  microcin ABC transporter ATP-binding protein [KO:K02031 K02032]
AZF01_21555  ABC transporter [KO:K02031 K02032]
AZF01_14525  ABC transporter ATP-binding protein [KO:K02031 K02032]
AZF01_01990  methionine ABC transporter ATP-binding protein [KO:K02031]
AZF01_07360  peptide ABC transporter ATP-binding protein [KO:K02031]
AZF01_03135  ABC transporter [KO:K02031]
AZF01_21290  dppD; peptide ABC transporter ATP-binding protein [KO:K02031]
AZF01_13065  peptide ABC transporter ATP-binding protein [KO:K02031]
AZF01_09470  dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein [KO:K02031]
AZF01_19200  peptide ABC transporter ATP-binding protein [KO:K02031]
AZF01_15175  peptide ABC transporter ATP-binding protein [KO:K02031]
AZF01_07860  ABC transporter ATP-binding protein [KO:K02031 K02032]
AZF01_21285  peptide ABC transporter ATP-binding protein [KO:K02032]
AZF01_15180  peptide ABC transporter ATP-binding protein [KO:K02032]
AZF01_19205  peptide ABC transporter ATP-binding protein [KO:K02032]
AZF01_09475  peptide ABC transporter ATP-binding protein [KO:K02032]
AZF01_10585  hypothetical protein [KO:K01635] [EC:4.1.2.40]
AZF01_12500  membrane protein insertase YidC [KO:K03217]
AZF01_06730  preprotein translocase subunit SecD [KO:K12257]
AZF01_13600  preprotein translocase subunit SecE [KO:K03073]
AZF01_11745  preprotein translocase subunit SecG [KO:K03075]
AZF01_05645  preprotein translocase subunit SecY [KO:K03076]
AZF01_06725  preprotein translocase [KO:K03210]
AZF01_18735  preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
AZF01_00190  cell division protein FtsY [KO:K03110]
AZF01_19255  preprotein translocase subunit SecB [KO:K03071]
AZF01_00220  RNA-binding protein [KO:K03106] [EC:3.6.5.4]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
PMID:25824838
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
  Journal
Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
Reference
PMID:19363118
  Authors
Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
  Title
Virulence gene regulation by the agr system in Clostridium perfringens.
  Journal
J Bacteriol 191:3919-27 (2009)
DOI:10.1128/JB.01455-08
Reference
PMID:22736963
  Authors
Li YH, Tian X
  Title
Quorum sensing and bacterial social interactions in biofilms.
  Journal
Sensors (Basel) 12:2519-38 (2012)
DOI:10.3390/s120302519
Reference
PMID:22407687
  Authors
Berg KH, Biornstad TJ, Johnsborg O, Havarstein LS
  Title
Properties and biological role of streptococcal fratricins.
  Journal
Appl Environ Microbiol 78:3515-22 (2012)
DOI:10.1128/AEM.00098-12
Reference
PMID:25475081
  Authors
Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP
  Title
Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
  Journal
J Oral Microbiol 6:26189 (2014)
DOI:10.3402/jom.v6.26189
Reference
PMID:25309879
  Authors
Jimenez JC, Federle MJ
  Title
Quorum sensing in group A Streptococcus.
  Journal
Front Cell Infect Microbiol 4:127 (2014)
DOI:10.3389/fcimb.2014.00127
Reference
PMID:24118108
  Authors
Cook LC, Federle MJ
  Title
Peptide pheromone signaling in Streptococcus and Enterococcus.
  Journal
FEMS Microbiol Rev 38:473-92 (2014)
DOI:10.1111/1574-6976.12046
Reference
PMID:9680220
  Authors
Podbielski A, Leonard BA
  Title
The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease.
  Journal
Mol Microbiol 28:1323-34 (1998)
DOI:10.1046/j.1365-2958.1998.00898.x
Reference
PMID:8885277
  Authors
Podbielski A, Pohl B, Woischnik M, Korner C, Schmidt KH, Rozdzinski E, Leonard BA
  Title
Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production.
  Journal
Mol Microbiol 21:1087-99 (1996)
DOI:10.1046/j.1365-2958.1996.661421.x
Reference
PMID:22636768
  Authors
Anbalagan S, Dmitriev A, McShan WM, Dunman PM, Chaussee MS
  Title
Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.
  Journal
J Bacteriol 194:3961-71 (2012)
DOI:10.1128/JB.06709-11
Reference
PMID:22016844
  Authors
Clewell DB
  Title
Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
  Journal
Mob Genet Elements 1:38-54 (2011)
DOI:10.4161/mge.1.1.15409
Reference
PMID:20734751
  Authors
Wardal E, Sadowy E, Hryniewicz W
  Title
Complex nature of enterococcal pheromone-responsive plasmids.
  Journal
Pol J Microbiol 59:79-87 (2010)
Reference
PMID:19683678
  Authors
Roux A, Payne SM, Gilmore MS
  Title
Microbial telesensing: probing the environment for friends, foes, and food.
  Journal
Cell Host Microbe 6:115-24 (2009)
DOI:10.1016/j.chom.2009.07.004
Reference
PMID:25089349
  Authors
Slamti L, Perchat S, Huillet E, Lereclus D
  Title
Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
  Journal
Toxins (Basel) 6:2239-55 (2014)
DOI:10.3390/toxins6082239
Reference
PMID:20030732
  Authors
Lopez D, Kolter R
  Title
Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis.
  Journal
FEMS Microbiol Rev 34:134-49 (2010)
DOI:10.1111/j.1574-6976.2009.00199.x
Reference
PMID:12897006
  Authors
Stephenson S, Mueller C, Jiang M, Perego M
  Title
Molecular analysis of Phr peptide processing in Bacillus subtilis.
  Journal
J Bacteriol 185:4861-71 (2003)
DOI:10.1128/JB.185.16.4861-4871.2003
Reference
PMID:17666034
  Authors
Lanigan-Gerdes S, Dooley AN, Faull KF, Lazazzera BA
  Title
Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
  Journal
Mol Microbiol 65:1321-33 (2007)
DOI:10.1111/j.1365-2958.2007.05869.x
Reference
PMID:15374644
  Authors
Kleerebezem M
  Title
Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis.
  Journal
Peptides 25:1405-14 (2004)
DOI:10.1016/j.peptides.2003.10.021
Reference
PMID:23125205
  Authors
Rutherford ST, Bassler BL
  Title
Bacterial quorum sensing: its role in virulence and possibilities for its control.
  Journal
Cold Spring Harb Perspect Med 2:a012427 (2012)
DOI:10.1101/cshperspect.a012427
Reference
PMID:23471618
  Authors
LaSarre B, Federle MJ
  Title
Exploiting quorum sensing to confuse bacterial pathogens.
  Journal
Microbiol Mol Biol Rev 77:73-111 (2013)
DOI:10.1128/MMBR.00046-12
Reference
PMID:18781869
  Authors
Sifri CD
  Title
Healthcare epidemiology: quorum sensing: bacteria talk sense.
  Journal
Clin Infect Dis 47:1070-6 (2008)
DOI:10.1086/592072
Related
pathway
maad02040  Flagellar assembly
KO pathway
ko02024   
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