Entry |
|
Name |
Valine, leucine and isoleucine biosynthesis - Mycobacterium canettii CIPT 140070008 |
Class |
Metabolism; Amino acid metabolism
|
Pathway map |
mcv00290 | Valine, leucine and isoleucine biosynthesis |
|
Module |
mcv_M00019 | Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:mcv00290] |
mcv_M00570 | Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:mcv00290] |
|
Other DBs |
|
Organism |
Mycobacterium canettii CIPT 140070008 [GN: mcv]
|
Gene |
BN43_40697 | leuC; Putative 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) [KO:K01703] [EC:4.2.1.33 4.2.1.35] |
BN43_40696 | leuD; Putative 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IMPI) [KO:K01704] [EC:4.2.1.33 4.2.1.35] |
BN43_40704 | leuB; Putative 3-Isppropylmalate dehydrogenase LeuB (Beta-IPM Dehydrogenase) (IMDH) (3-IPM-DH) [KO:K00052] [EC:1.1.1.85] |
BN43_40716 | ilvB; Putative acetolactate synthase (large subunit) IlvB1 (acetohydroxy-acid synthase) [KO:K01652] [EC:2.2.1.6] |
BN43_40714 | ilvC; Putative ketol-acid reductoisomerase IlvC (acetohydroxy-acid isomeroreductase) (alpha-keto-beta-hydroxylacil reductoisomerase) [KO:K00053] [EC:1.1.1.86] |
BN43_90218 | leuA; 2-isopropylmalate synthase LeuA (Alpha-Isopropylmalate Synthase) (alpha-IPM synthetase) [KO:K01649] [EC:2.3.3.13] |
|
Compound |
C00141 | 3-Methyl-2-oxobutanoic acid |
C00233 | 4-Methyl-2-oxopentanoate |
C00671 | (S)-3-Methyl-2-oxopentanoic acid |
C04181 | 3-Hydroxy-3-methyl-2-oxobutanoic acid |
C04236 | (2S)-2-Isopropyl-3-oxosuccinate |
C04272 | (R)-2,3-Dihydroxy-3-methylbutanoate |
C04411 | (2R,3S)-3-Isopropylmalate |
C06006 | (S)-2-Aceto-2-hydroxybutanoate |
C06007 | (R)-2,3-Dihydroxy-3-methylpentanoate |
C06032 | D-erythro-3-Methylmalate |
C14463 | (R)-3-Hydroxy-3-methyl-2-oxopentanoate |
|
Reference |
|
Authors |
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G. |
Title |
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway. |
Journal |
|
Related pathway |
mcv00260 | Glycine, serine and threonine metabolism |
mcv00280 | Valine, leucine and isoleucine degradation |
|
KO pathway |
|
LinkDB |
|