KEGG   PATHWAY: mint02010
Entry
mint02010                   Pathway                                
Name
ABC transporters - Mixta intestinalis
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
mint02010  ABC transporters
mint02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Mixta intestinalis [GN:mint]
Gene
C7M51_02272  cysP; Thiosulfate-binding protein [KO:K02048]
C7M51_03284  sbp; Sulfate-binding protein [KO:K23163]
C7M51_02271  cysT; Sulfate transport system permease protein CysT [KO:K02046]
C7M51_02270  cysW_2; Sulfate transport system permease protein CysW [KO:K02047]
C7M51_02269  cysA_2; Sulfate/thiosulfate import ATP-binding protein CysA [KO:K02045] [EC:7.3.2.3]
C7M51_03884  tauA; Taurine-binding periplasmic protein [KO:K15551]
C7M51_03886  ssuC_2; Putative aliphatic sulfonates transport permease protein SsuC [KO:K15552]
C7M51_03885  tauB; Taurine import ATP-binding protein TauB [KO:K10831] [EC:7.6.2.7]
C7M51_00777  ssuA; Putative aliphatic sulfonates-binding protein [KO:K15553]
C7M51_00775  ssuC_1; Putative aliphatic sulfonates transport permease protein SsuC [KO:K15554]
C7M51_00774  ssuB; Aliphatic sulfonates import ATP-binding protein SsuB [KO:K15555] [EC:7.6.2.14]
C7M51_00604  modA; Molybdate-binding periplasmic protein [KO:K02020]
C7M51_00605  modB; Molybdenum transport system permease protein ModB [KO:K02018]
C7M51_00606  cysA_1; Sulfate/thiosulfate import ATP-binding protein CysA [KO:K02017] [EC:7.3.2.5]
C7M51_00601  ylmA; putative ABC transporter ATP-binding protein YlmA [KO:K05776]
C7M51_00007  thiB; Thiamine-binding periplasmic protein [KO:K02064]
C7M51_00006  cysW_1; Sulfate transport system permease protein CysW [KO:K02063]
C7M51_00005  thiQ; Thiamine import ATP-binding protein ThiQ [KO:K02062] [EC:7.6.2.15]
C7M51_00937  potD; Spermidine/putrescine-binding periplasmic protein [KO:K11069]
C7M51_00938  ydcV_2; Inner membrane ABC transporter permease protein YdcV [KO:K11070]
C7M51_00940  potB; Spermidine/putrescine transport system permease protein PotB [KO:K11071]
C7M51_00941  potA_2; Spermidine/putrescine import ATP-binding protein PotA [KO:K11072] [EC:7.6.2.11]
C7M51_00706  potF; Putrescine-binding periplasmic protein [KO:K11073]
C7M51_00709  ydcV_1; Inner membrane ABC transporter permease protein YdcV [KO:K11074]
C7M51_00708  potH; Putrescine transport system permease protein PotH [KO:K11075]
C7M51_00707  potA_1; Spermidine/putrescine import ATP-binding protein PotA [KO:K11076] [EC:7.6.2.16]
C7M51_01230  osmX; Osmoprotectant-binding protein OsmX [KO:K05845]
C7M51_00654  yehZ; Glycine betaine-binding protein YehZ [KO:K05845]
C7M51_01229  osmW; Osmoprotectant import permease protein OsmW [KO:K05846]
C7M51_01231  osmY_1; Osmoprotectant import permease protein OsmY [KO:K05846]
C7M51_00655  yehY; Glycine betaine uptake system permease protein YehY [KO:K05846]
C7M51_00657  yehW; Glycine betaine uptake system permease protein YehW [KO:K05846]
C7M51_01228  osmV; Osmoprotectant import ATP-binding protein OsmV [KO:K05847] [EC:7.6.2.9]
C7M51_00656  yehX; Glycine betaine uptake system ATP-binding protein YehX [KO:K05847] [EC:7.6.2.9]
C7M51_03094  malE; Maltose-binding periplasmic protein [KO:K10108]
C7M51_03095  malF; Maltose transport system permease protein MalF [KO:K10109]
C7M51_03096  malG; Maltose transport system permease protein MalG [KO:K10110]
C7M51_03093  malK; Maltose/maltodextrin import ATP-binding protein MalK [KO:K10111] [EC:7.5.2.-]
C7M51_00267  yesO; Putative ABC transporter substrate-binding protein YesO [KO:K10192]
C7M51_00264  lacF; Lactose transport system permease protein LacF [KO:K10193]
C7M51_00265  araQ; L-arabinose transport system permease protein AraQ [KO:K10194]
C7M51_00266  sugC; Trehalose import ATP-binding protein SugC [KO:K10195]
C7M51_04030  mlaC; putative phospholipid-binding protein MlaC [KO:K07323]
C7M51_04029  mlaD; putative phospholipid ABC transporter-binding protein MlaD [KO:K02067]
C7M51_04028  mlaE; putative phospholipid ABC transporter permease protein MlaE [KO:K02066]
C7M51_04031  mlaB; putative phospholipid ABC transporter-binding protein MlaB [KO:K07122]
C7M51_04027  mlaF; putative phospholipid import ATP-binding protein MlaF [KO:K02065]
C7M51_03455  rbsB; Ribose import binding protein RbsB [KO:K10439]
C7M51_03456  rbsC_2; Ribose import permease protein RbsC [KO:K10440]
C7M51_03457  rbsA_2; Ribose import ATP-binding protein RbsA [KO:K10441] [EC:7.5.2.7]
C7M51_03458  rbsD_1; D-ribose pyranase [KO:K06726] [EC:5.4.99.62]
C7M51_01214  araF; L-arabinose-binding periplasmic protein [KO:K10537]
C7M51_01216  rbsC_1; Ribose import permease protein RbsC [KO:K10538]
C7M51_01215  araG; Arabinose import ATP-binding protein AraG [KO:K10539] [EC:7.5.2.12]
C7M51_01207  ytfQ; ABC transporter periplasmic-binding protein YtfQ [KO:K23508]
C7M51_01209  ytfT; Inner membrane ABC transporter permease protein YtfT [KO:K23509]
C7M51_01210  yjfF; Inner membrane ABC transporter permease protein YjfF [KO:K23509]
C7M51_01208  rbsA_1; Ribose import ATP-binding protein RbsA [KO:K10820] [EC:7.5.2.9]
C7M51_01987  mglB; D-galactose-binding periplasmic protein [KO:K10540]
C7M51_01985  mglC; Galactoside transport system permease protein MglC [KO:K10541]
C7M51_01986  mglA; Galactose/methyl galactoside import ATP-binding protein MglA [KO:K10542] [EC:7.5.2.11]
C7M51_03629  xylF; D-xylose-binding periplasmic protein [KO:K10543]
C7M51_03627  xylH; Xylose transport system permease protein XylH [KO:K10544]
C7M51_03628  xylG; Xylose import ATP-binding protein XylG [KO:K10545] [EC:7.5.2.10]
C7M51_03786  ugpB; sn-glycerol-3-phosphate-binding periplasmic protein UgpB [KO:K05813]
C7M51_03787  ugpA; sn-glycerol-3-phosphate transport system permease protein UgpA [KO:K05814]
C7M51_03788  lacG; Lactose transport system permease protein LacG [KO:K05815]
C7M51_03789  ugpC; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K05816] [EC:7.6.2.10]
C7M51_00367  pstS_1; Phosphate-binding protein PstS [KO:K02040]
C7M51_03485  pstS_2; Phosphate-binding protein PstS [KO:K02040]
C7M51_02325  pstC1; Phosphate transport system permease protein PstC 1 [KO:K02037]
C7M51_03486  pstC; Phosphate transport system permease protein PstC [KO:K02037]
C7M51_02324  pstA_1; Phosphate transport system permease protein PstA [KO:K02038]
C7M51_03487  pstA_2; Phosphate transport system permease protein PstA [KO:K02038]
C7M51_02323  pstB3; Phosphate import ATP-binding protein PstB 3 [KO:K02036] [EC:7.3.2.1]
C7M51_03488  pstB; Phosphate import ATP-binding protein PstB [KO:K02036] [EC:7.3.2.1]
C7M51_02117  hisM; Histidine transport system permease protein HisM [KO:K10015]
C7M51_02118  hisQ; Histidine transport system permease protein HisQ [KO:K10016]
C7M51_02116  hisP; Histidine transport ATP-binding protein HisP [KO:K10017] [EC:7.4.2.1]
C7M51_02119  argT; Lysine/arginine/ornithine-binding periplasmic protein [KO:K10014]
C7M51_00712  artJ; ABC transporter arginine-binding protein 1 [KO:K09996]
C7M51_00715  artI; Putative ABC transporter arginine-binding protein 2 [KO:K09997]
C7M51_00713  artM_1; Arginine ABC transporter permease protein ArtM [KO:K09998]
C7M51_00714  artQ; Arginine ABC transporter permease protein ArtQ [KO:K09999]
C7M51_00716  artP; Arginine transport ATP-binding protein ArtP [KO:K10000] [EC:7.4.2.1]
C7M51_00523  gltI; Glutamate/aspartate import solute-binding protein [KO:K10001]
C7M51_00521  gltK; Glutamate/aspartate import permease protein GltK [KO:K10002]
C7M51_00522  glnM_1; putative glutamine ABC transporter permease protein GlnM [KO:K10003]
C7M51_00520  glnQ_1; Glutamine transport ATP-binding protein GlnQ [KO:K10004] [EC:7.4.2.1]
C7M51_03961  yhdW; Putative amino-acid ABC transporter-binding protein YhdW [KO:K09969]
C7M51_03960  glnM_2; putative glutamine ABC transporter permease protein GlnM [KO:K09970]
C7M51_03959  yhdY; Inner membrane amino-acid ABC transporter permease protein YhdY [KO:K09971]
C7M51_03958  glnQ_2; Glutamine transport ATP-binding protein GlnQ [KO:K09972] [EC:7.4.2.1]
C7M51_01735  fliY; L-cystine-binding protein FliY [KO:K02424]
C7M51_01734  yecS; L-cystine transport system permease protein YecS [KO:K10009]
C7M51_01733  artM_2; Arginine transport ATP-binding protein ArtM [KO:K10010] [EC:7.4.2.1]
C7M51_01252  braC; Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999]
C7M51_03781  livJ; Leu/Ile/Val-binding protein [KO:K01999]
C7M51_01248  livH_1; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
C7M51_03782  livH_3; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
C7M51_01249  livH_2; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01998]
C7M51_03783  hypothetical protein [KO:K01998]
C7M51_01250  lptB_1; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995]
C7M51_03784  lptB_2; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995]
C7M51_01251  livF_2; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
C7M51_03785  livF_3; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
C7M51_01256  metQ_2; Methionine-binding lipoprotein MetQ [KO:K02073]
C7M51_01719  Membrane lipoprotein TpN32 [KO:K02073]
C7M51_00158  metQ_1; D-methionine-binding lipoprotein MetQ [KO:K02073]
C7M51_01257  metP; Methionine import system permease protein MetP [KO:K02072]
C7M51_01721  metI_2; D-methionine transport system permease protein MetI [KO:K02072]
C7M51_00159  metI_1; D-methionine transport system permease protein MetI [KO:K02072]
C7M51_01258  metN_2; Methionine import ATP-binding protein MetN [KO:K02071]
C7M51_01720  metN_3; Methionine import ATP-binding protein MetN [KO:K02071]
C7M51_00160  metN_1; Methionine import ATP-binding protein MetN [KO:K02071]
C7M51_00618  livF_1; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K11963]
C7M51_01458  oppA_1; Periplasmic oligopeptide-binding protein [KO:K15580]
C7M51_01459  oppA_2; Periplasmic oligopeptide-binding protein [KO:K15580]
C7M51_01457  oppB; Oligopeptide transport system permease protein OppB [KO:K15581]
C7M51_01456  oppC; Oligopeptide transport system permease protein OppC [KO:K15582]
C7M51_01455  oppD_2; Oligopeptide transport ATP-binding protein OppD [KO:K15583]
C7M51_01454  oppF_1; Oligopeptide transport ATP-binding protein OppF [KO:K10823]
C7M51_03659  dppA; Periplasmic dipeptide transport protein [KO:K12368]
C7M51_03660  dppB_2; Dipeptide transport system permease protein DppB [KO:K12369]
C7M51_03661  dppC; Dipeptide transport system permease protein DppC [KO:K12370]
C7M51_03662  sapD_2; Peptide transport system ATP-binding protein SapD [KO:K12371]
C7M51_03663  oppF_2; Oligopeptide transport ATP-binding protein OppF [KO:K12372]
C7M51_01389  sapA; Peptide transport periplasmic protein SapA [KO:K19226]
C7M51_01390  sapB; Putrescine export system permease protein SapB [KO:K19227]
C7M51_01391  sapC; Peptide transport system permease protein SapC [KO:K19228]
C7M51_01392  sapD_1; Putrescine export system ATP-binding protein SapD [KO:K19229]
C7M51_01393  sapF; Peptide transport system ATP-binding protein SapF [KO:K19230]
C7M51_00682  gsiB; Glutathione-binding protein GsiB [KO:K13889]
C7M51_00683  gsiC; Glutathione transport system permease protein GsiC [KO:K13890]
C7M51_00684  gsiD; Glutathione transport system permease protein GsiD [KO:K13891]
C7M51_00681  gsiA_1; Glutathione import ATP-binding protein GsiA [KO:K13892]
C7M51_02013  appA; Oligopeptide-binding protein AppA [KO:K13893]
C7M51_02014  yejB; Inner membrane ABC transporter permease protein YejB [KO:K13894]
C7M51_02015  yejE; Inner membrane ABC transporter permease protein YejE [KO:K13895]
C7M51_02016  gsiA_2; Glutathione import ATP-binding protein GsiA [KO:K13896]
C7M51_02062  fepB; Ferrienterobactin-binding periplasmic protein [KO:K23185]
C7M51_00114  fhuD; Iron(3+)-hydroxamate-binding protein FhuD [KO:K23227]
C7M51_00115  fhuB; Iron(3+)-hydroxamate import system permease protein FhuB [KO:K23228]
C7M51_00113  fhuC; Iron(3+)-hydroxamate import ATP-binding protein FhuC [KO:K10829] [EC:7.2.2.16]
C7M51_00120  btuF_1; Vitamin B12-binding protein [KO:K06858]
C7M51_01150  btuC; Vitamin B12 import system permease protein BtuC [KO:K06073]
C7M51_01152  btuD; Vitamin B12 import ATP-binding protein BtuD [KO:K06074] [EC:7.6.2.8]
C7M51_01635  znuA; High-affinity zinc uptake system protein ZnuA [KO:K09815]
C7M51_01637  znuB; High-affinity zinc uptake system membrane protein ZnuB [KO:K09816]
C7M51_01636  znuC; Zinc import ATP-binding protein ZnuC [KO:K09817] [EC:7.2.2.20]
C7M51_00932  lolC; Lipoprotein-releasing system transmembrane protein LolC [KO:K09808]
C7M51_00934  lolE; Lipoprotein-releasing system transmembrane protein LolE [KO:K09808]
C7M51_00933  lolD_2; Lipoprotein-releasing system ATP-binding protein LolD [KO:K09810] [EC:7.6.2.-]
C7M51_02157  ccmD; Heme exporter protein D [KO:K02196]
C7M51_02158  ccmC; Heme exporter protein C [KO:K02195]
C7M51_02159  ccmB; Heme exporter protein B [KO:K02194]
C7M51_02160  ccmA; Cytochrome c biogenesis ATP-binding export protein CcmA [KO:K02193] [EC:7.6.2.5]
C7M51_04095  lptF; Lipopolysaccharide export system permease protein LptF [KO:K07091]
C7M51_04096  lptG; Lipopolysaccharide export system permease protein LptG [KO:K11720]
C7M51_04021  lptB_3; Lipopolysaccharide export system ATP-binding protein LptB [KO:K06861] [EC:7.5.2.5]
C7M51_03778  ftsX; Cell division protein FtsX [KO:K09811]
C7M51_03777  ftsE; Cell division ATP-binding protein FtsE [KO:K09812]
C7M51_00752  msbA; Lipid A export ATP-binding/permease protein MsbA [KO:K11085] [EC:7.5.2.6]
C7M51_00417  yheI; putative multidrug resistance ABC transporter ATP-binding/permease protein YheI [KO:K18889]
C7M51_00418  mdlB; Multidrug resistance-like ATP-binding protein MdlB [KO:K18890]
C7M51_03496  hlyB; Alpha-hemolysin translocation ATP-binding protein HlyB [KO:K13409]
C7M51_03708  Putative multidrug export ATP-binding/permease protein [KO:K18893]
C7M51_02042  apxIB; Toxin RTX-I translocation ATP-binding protein [KO:K12541]
C7M51_03259  prsD; Type I secretion system ATP-binding protein PrsD [KO:K12536]
C7M51_00732  Putative multidrug export ATP-binding/permease protein [KO:K16012]
C7M51_00733  cydD; ATP-binding/permease protein CydD [KO:K16013]
C7M51_02267  macB; Macrolide export ATP-binding/permease protein MacB [KO:K05685] [EC:7.6.2.-]
C7M51_02036  yojI; ABC transporter ATP-binding/permease protein YojI [KO:K06159]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
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J Bacteriol 190:4460-9 (2008)
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The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
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Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
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