KEGG   PATHWAY: paf00630
Entry
paf00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas aeruginosa M18
Class
Metabolism; Carbohydrate metabolism
Pathway map
paf00630  Glyoxylate and dicarboxylate metabolism
paf00630

Module
paf_M00621  Glycine cleavage system [PATH:paf00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas aeruginosa M18 [GN:paf]
Gene
PAM18_2341  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
PAM18_4841  acsB; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
PAM18_4152  acsA; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
PAM18_2483  putative AMP-binding enzyme [KO:K01895] [EC:6.2.1.1]
PAM18_0481  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
PAM18_3467  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
PAM18_3486  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
PAM18_3259  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
PAM18_3044  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PAM18_3310  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PAM18_1015  putative acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PAM18_2485  putative acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PAM18_4894  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PAM18_1666  phaJ1; (R)-specific enoyl-CoA hydratase [KO:K17865] [EC:4.2.1.55]
PAM18_5475  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
PAM18_5474  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
PAM18_5473  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
PAM18_4707  katB; catalase [KO:K03781] [EC:1.11.1.6]
PAM18_2892  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
PAM18_0694  katA; catalase [KO:K03781] [EC:1.11.1.6]
PAM18_1044  putative 2-hydroxyacid dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
PAM18_4721  hprA; glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
PAM18_1987  putative hydrolase [KO:K01091] [EC:3.1.3.18]
PAM18_0609  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
PAM18_0066  putative phosphatase [KO:K01091] [EC:3.1.3.18]
PAM18_0291  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PAM18_0293  spuB; putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PAM18_1609  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PAM18_3004  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PAM18_3482  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PAM18_5233  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PAM18_5629  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PAM18_5644  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PAM18_4696  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PAM18_2589  glyA2; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PAM18_5535  glyA1; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PAM18_2588  gcvP2; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
PAM18_5331  gcvP1; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
PAM18_2591  gcvT2; glycine cleavage system protein T2 [KO:K00605] [EC:2.1.2.10]
PAM18_5333  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
PAM18_3460  lpdG; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
PAM18_2790  lpdV; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
PAM18_4940  lpd3; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
PAM18_2587  gcvH2; glycine cleavage system protein H [KO:K02437]
PAM18_5332  gcvH1; glycine cleavage system protein H [KO:K02437]
PAM18_4905  putative glycine cleavage system H protein [KO:K02437]
PAM18_3629  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
PAM18_3630  putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
PAM18_3631  putative oxidoreductase [KO:K00042] [EC:1.1.1.60]
PAM18_3993  Putative glycerate kinase [KO:K00865] [EC:2.7.1.165]
PAM18_3632  putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
PAM18_1791  keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
PAM18_1832  putative aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
PAM18_4921  fdnG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
PAM18_4922  Twin-arginine translocation pathway signal [KO:K00123] [EC:1.17.1.9]
PAM18_4920  fdnH; nitrate-inducible formate dehydrogenase, beta subunit [KO:K00124]
PAM18_4919  fdnI; nitrate-inducible formate dehydrogenase, gamma subunit [KO:K00127]
PAM18_2962  kynB; kynurenine formamidase, KynB [KO:K07130] [EC:3.5.1.9]
PAM18_4404  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
PAM18_5540  purU2; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
PAM18_5205  hutG; N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
paf00010  Glycolysis / Gluconeogenesis
paf00020  Citrate cycle (TCA cycle)
paf00030  Pentose phosphate pathway
paf00053  Ascorbate and aldarate metabolism
paf00071  Fatty acid degradation
paf00230  Purine metabolism
paf00250  Alanine, aspartate and glutamate metabolism
paf00260  Glycine, serine and threonine metabolism
paf00620  Pyruvate metabolism
paf00710  Carbon fixation by Calvin cycle
paf00750  Vitamin B6 metabolism
paf00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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