Entry
Name
ABC transporters - Proteus terrae subsp. cibarius
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Proteus terrae subsp. cibarius [GN:
pcib ]
Gene
F9282_15510 thiP; thiamine/thiamine pyrophosphate ABC transporter permease ThiP [KO:K02063 ]
F9282_17505 potD; spermidine/putrescine ABC transporter substrate-binding protein PotD [KO:K11069 ]
F9282_04620 proX; glycine betaine/L-proline ABC transporter substrate-binding protein ProX [KO:K02002 ]
F9282_04625 proW; glycine betaine/L-proline ABC transporter permease ProW [KO:K02001 ]
F9282_02530 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
F9282_02525 mlaE; lipid asymmetry maintenance ABC transporter permease subunit MlaE [KO:K02066 ]
F9282_02295 ugpB; sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB [KO:K05813 ]
F9282_18600 pstS; phosphate ABC transporter substrate-binding protein PstS [KO:K02040 ]
F9282_10600 oppA; oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
F9282_18825 nikA; nickel ABC transporter, nickel/metallophore periplasmic binding protein [KO:K15584 ]
F9282_03800 btuF; vitamin B12 ABC transporter substrate-binding protein BtuF [KO:K06858 ]
F9282_10290 energy-coupling factor transporter transmembrane protein EcfT [KO:K16785 ]
F9282_10295 energy-coupling factor ABC transporter ATP-binding protein [KO:K16786 ] [EC:7.-.-.-]
F9282_07625 lolC; lipoprotein-releasing ABC transporter permease subunit LolC [KO:K09808 ]
F9282_07635 lolE; lipoprotein-releasing ABC transporter permease subunit LolE [KO:K09808 ]
F9282_07630 lolD; lipoprotein-releasing ABC transporter ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
F9282_03380 SmdA family multidrug ABC transporter permease/ATP-binding protein [KO:K18889 ]
F9282_03385 SmdB family multidrug efflux ABC transporter permease/ATP-binding protein [KO:K18890 ]
F9282_05705 cydC; cysteine/glutathione ABC transporter ATP-binding protein/permease CydC [KO:K16012 ]
F9282_05710 cydD; cysteine/glutathione ABC transporter permease/ATP-binding protein CydD [KO:K16013 ]
F9282_05675 macB; macrolide ABC transporter ATP-binding protein/permease MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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