KEGG   PATHWAY: pkh00630
Entry
pkh00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas khazarica
Class
Metabolism; Carbohydrate metabolism
Pathway map
pkh00630  Glyoxylate and dicarboxylate metabolism
pkh00630

Module
pkh_M00621  Glycine cleavage system [PATH:pkh00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas khazarica [GN:pkh]
Gene
JLK41_11945  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
JLK41_14040  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
JLK41_17625  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
JLK41_19940  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
JLK41_22390  malate synthase G [KO:K01638] [EC:2.3.3.9]
JLK41_00825  malate synthase G [KO:K01638] [EC:2.3.3.9]
JLK41_11315  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
JLK41_15635  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
JLK41_10835  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
JLK41_03925  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
JLK41_05680  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
JLK41_05835  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
JLK41_05855  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
JLK41_10775  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
JLK41_14030  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
JLK41_20265  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
JLK41_21190  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
JLK41_07755  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
JLK41_00845  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
JLK41_00840  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
JLK41_00835  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
JLK41_20275  2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
JLK41_08370  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
JLK41_21880  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
JLK41_24480  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
JLK41_10575  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
JLK41_14870  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
JLK41_16385  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
JLK41_22610  glnA; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
JLK41_24005  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
JLK41_24840  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
JLK41_01655  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
JLK41_01660  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
JLK41_04030  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
JLK41_06980  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
JLK41_22575  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
JLK41_06985  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
JLK41_06975  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
JLK41_14795  aminomethyltransferase family protein [KO:K00605] [EC:2.1.2.10]
JLK41_14830  aminomethyltransferase family protein [KO:K00605] [EC:2.1.2.10]
JLK41_01605  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
JLK41_05515  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
JLK41_11350  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
JLK41_03870  glycine cleavage system protein H [KO:K02437]
JLK41_06990  gcvH; glycine cleavage system protein GcvH [KO:K02437]
JLK41_01610  gcvH; glycine cleavage system protein GcvH [KO:K02437]
JLK41_15905  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
JLK41_15910  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
JLK41_18200  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
JLK41_15915  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
JLK41_07460  glycerate kinase [KO:K00865] [EC:2.7.1.165]
JLK41_15920  glycerate kinase [KO:K11529] [EC:2.7.1.165]
JLK41_13055  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
JLK41_13165  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
JLK41_17750  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
JLK41_02365  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
JLK41_02360  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
JLK41_03775  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
JLK41_02355  formate dehydrogenase [KO:K00124]
JLK41_03780  fdxH; formate dehydrogenase subunit beta [KO:K00124]
JLK41_02350  formate dehydrogenase subunit gamma [KO:K00127]
JLK41_03785  formate dehydrogenase subunit gamma [KO:K00127]
JLK41_18280  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
JLK41_18410  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
JLK41_22550  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
JLK41_04240  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pkh00010  Glycolysis / Gluconeogenesis
pkh00020  Citrate cycle (TCA cycle)
pkh00030  Pentose phosphate pathway
pkh00053  Ascorbate and aldarate metabolism
pkh00071  Fatty acid degradation
pkh00230  Purine metabolism
pkh00250  Alanine, aspartate and glutamate metabolism
pkh00260  Glycine, serine and threonine metabolism
pkh00620  Pyruvate metabolism
pkh00710  Carbon fixation by Calvin cycle
pkh00750  Vitamin B6 metabolism
pkh00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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