Entry Name Bacterial chemotaxis - Pseudomonas protegens Cab57
Description Chemotaxis is the process by which cells sense chemical gradients in their environment and then move towards more favorable conditions. In chemotaxis, events at the receptors control autophosphorylation of the CheA histidine kinase, and the phosphohistidine is the substrate for the response regulator CheY, which catalyzes the transfer of the phosphoryl group to a conserved aspartate. The resulting CheY-P can interact with the switch mechanism in the motor. This interaction causes a change in behavior, such as in direction or speed of rotation of flagella.
Class Cellular Processes; Cell motilityBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Pseudomonas protegens Cab57 [GN:
ppro ]
Gene PPC_5980 histidine kinase, HAMP region: chemotaxis sensory transducer [KO:K03406 ]
PPC_2442 histidine kinase, HAMP region: chemotaxis sensory transducer [KO:K03406 ]
PPC_4692 methyl-accepting chemotaxis transducer/sensory box protein [KO:K03406 ]
PPC_5192 methyl-accepting chemotaxis transducer/sensory box protein [KO:K03406 ]
PPC_5193 methyl-accepting chemotaxis transducer/sensory box protein [KO:K03406 ]
PPC_3379 histidine kinase, HAMP region: chemotaxis sensory transducer [KO:K03406 ]
PPC_0503 histidine kinase, HAMP region: chemotaxis sensory transducer [KO:K03406 ]
PPC_0504 histidine kinase, HAMP region: chemotaxis sensory transducer [KO:K03406 ]
PPC_0130 Cache sensor-containing chemotaxis sensory transducer [KO:K03406 ]
PPC_1583 histidine kinase, HAMP region: chemotaxis sensory transducer [KO:K03406 ]
PPC_1789 histidine kinase, HAMP region: chemotaxis sensory transducer [KO:K03406 ]
PPC_2581 histidine kinase, HAMP region: chemotaxis sensory transducer [KO:K03406 ]
PPC_4792 Cache sensor-containing chemotaxis sensory transducer [KO:K03406 ]
PPC_2114 periplasmic binding protein/LacI transcriptional regulator [KO:K10439 ]
PPC_0912 dipeptide ABC transporter periplasmic dipeptide-binding protein [KO:K12368 ]
PPC_0914 nikA2; nickel ABC transporter periplasmic nickel-binding protein [KO:K12368 ]
PPC_0915 nikA3; nickel ABC transporter periplasmic nickel-binding protein [KO:K12368 ]
Compound Reference Authors Kristich CJ, Ordal GW.
Title Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis.
Journal Reference Authors Kirby JR, Kristich CJ, Saulmon MM, Zimmer MA, Garrity LF, Zhulin IB, Ordal GW.
Title CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.
Journal Reference Authors Szurmant H, Bunn MW, Cannistraro VJ, Ordal GW.
Title Bacillus subtilis hydrolyzes CheY-P at the location of its action, the flagellar switch.
Journal Reference Authors Szurmant H, Muff TJ, Ordal GW.
Title Bacillus subtilis CheC and FliY are members of a novel class of CheY-P-hydrolyzing proteins in the chemotactic signal transduction cascade.
Journal Reference Authors Yoshihara S, Geng X, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M.
Title Mutational analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803.
Journal Reference Authors Darzins A.
Title The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.
Journal Reference Authors Szurmant H, Ordal GW
Title Diversity in chemotaxis mechanisms among the bacteria and archaea.
Journal Reference Authors Rao CV, Glekas GD, Ordal GW
Title The three adaptation systems of Bacillus subtilis chemotaxis.
Journal Reference Authors Muff TJ, Ordal GW
Title The diverse CheC-type phosphatases: chemotaxis and beyond.
Journal Reference Authors Miller LD, Russell MH, Alexandre G
Title Diversity in bacterial chemotactic responses and niche adaptation.
Journal Related KO pathway LinkDB All DBs
