KEGG   PATHWAY: psec00630
Entry
psec00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas sp. CCOS 191
Class
Metabolism; Carbohydrate metabolism
Pathway map
psec00630  Glyoxylate and dicarboxylate metabolism
psec00630

Module
psec_M00621  Glycine cleavage system [PATH:psec00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas sp. CCOS 191 [GN:psec]
Gene
CCOS191_1965  aceA; Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
CCOS191_1428  acsA1b; Acetyl-coenzyme A synthetase 1 [KO:K01895] [EC:6.2.1.1]
CCOS191_0704  acsA2; Acetyl-coenzyme A synthetase 2 [KO:K01895] [EC:6.2.1.1]
CCOS191_1698  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
CCOS191_4968  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
CCOS191_1612  gltA; Citrate synthase [KO:K01647] [EC:2.3.3.1]
CCOS191_3614  acnA2; Aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
CCOS191_1804  acnB; Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
CCOS191_2274  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CCOS191_2956  bktB; Beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
CCOS191_0794  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CCOS191_0869  atoB; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CCOS191_1700  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CCOS191_3933  3-hydroxybutyryl-CoA dehydratase [KO:K17865] [EC:4.2.1.55]
CCOS191_3057  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
CCOS191_2988  glcD; Glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
CCOS191_2989  glcE; Glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
CCOS191_2990  glcF; Glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
CCOS191_2961  catalase [KO:K03781] [EC:1.11.1.6]
CCOS191_4841  katA; Catalase [KO:K03781] [EC:1.11.1.6]
CCOS191_0072  katE; Catalase HPII [KO:K03781] [EC:1.11.1.6]
CCOS191_0886  ghrB1; Glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
CCOS191_4539  hprA; Glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
CCOS191_4906  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
CCOS191_3772  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
CCOS191_0050  5'-nucleotidase [KO:K01091] [EC:3.1.3.18]
CCOS191_2822  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CCOS191_5193  puuA2; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
CCOS191_3928  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CCOS191_3329  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CCOS191_1454  glutamate-ammonia ligase [KO:K01915] [EC:6.3.1.2]
CCOS191_0226  puuA1; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
CCOS191_0227  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CCOS191_0439  glnA; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CCOS191_5005  glyA1; Serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
CCOS191_4643  glyA2; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
CCOS191_0218  gcvP2; Glycine dehydrogenase [decarboxylating] 2 [KO:K00281] [EC:1.4.4.2]
CCOS191_1000  gcvP1; Glycine dehydrogenase [decarboxylating] 1 [KO:K00281] [EC:1.4.4.2]
CCOS191_0216  gcvT1; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
CCOS191_0998  gcvT2; Aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
CCOS191_5262  lpd3; Dihydrolipoyl dehydrogenase 3 [KO:K00382] [EC:1.8.1.4]
CCOS191_1449  lpdV; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CCOS191_1619  lpdG; Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
CCOS191_0217  gcvH2; Glycine cleavage system H protein 2 [KO:K02437]
CCOS191_1001  gcvH1; Glycine cleavage system H protein 1 [KO:K02437]
CCOS191_3718  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
CCOS191_3719  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CCOS191_3720  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CCOS191_2228  glxK; Glycerate kinase [KO:K00865] [EC:2.7.1.165]
CCOS191_3721  ttuD; putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
CCOS191_3068  Tartrate dehydrogenase/decarboxylase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
CCOS191_1029  eda; 2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CCOS191_3483  hypothetical protein [KO:K00126] [EC:1.17.1.9]
CCOS191_3484  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
CCOS191_4834  fdoG1; Formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
CCOS191_4835  fdoG2; Formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
CCOS191_3485  formate dehydrogenase subunit beta [KO:K00124]
CCOS191_4833  fdoH; Formate dehydrogenase-O iron-sulfur subunit [KO:K00124]
CCOS191_3486  formate dehydrogenase subunit gamma [KO:K00127]
CCOS191_4832  fdoI; Formate dehydrogenase, cytochrome b556(fdo) subunit [KO:K00127]
CCOS191_5000  purU2; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
CCOS191_4285  purU1; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
CCOS191_0457  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
psec00010  Glycolysis / Gluconeogenesis
psec00020  Citrate cycle (TCA cycle)
psec00030  Pentose phosphate pathway
psec00053  Ascorbate and aldarate metabolism
psec00071  Fatty acid degradation
psec00230  Purine metabolism
psec00250  Alanine, aspartate and glutamate metabolism
psec00260  Glycine, serine and threonine metabolism
psec00620  Pyruvate metabolism
psec00710  Carbon fixation by Calvin cycle
psec00750  Vitamin B6 metabolism
psec00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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