Entry Name ABC transporters - Providencia stuartii MRSN 2154
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Providencia stuartii MRSN 2154 [GN:
psi ]
Gene S70_02870 cysW; sulfate/thiosulfate transporter permease subunit [KO:K02047 ]
S70_01490 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein [KO:K15553 ]
S70_15880 putative molybdenum transport ATP-binding protein ModF [KO:K05776 ]
S70_12885 potD; spermidine/putrescine ABC transporter periplasmic substrate-binding protein [KO:K11069 ]
S70_12880 potC; spermidine/putrescine ABC transporter membrane protein [KO:K11070 ]
S70_12875 potB; spermidine/putrescine ABC transporter membrane protein [KO:K11071 ]
S70_15275 proX; glycine betaine transporter periplasmic subunit [KO:K02002 ]
S70_19785 periplasmic binding protein/LacI transcriptional regulator [KO:K17208 ]
S70_09200 phosphate ABC transporter periplasmic substrate-binding protein PstS [KO:K02040 ]
S70_15405 polar amino acid ABC transporter inner membrane subunit [KO:K10003 ]
S70_13710 leucine ABC transporter subunit substrate-binding protein LivK [KO:K01999 ]
S70_13715 branched-chain amino acid transporter permease subunit LivH [KO:K01997 ]
S70_13720 livM; leucine/isoleucine/valine transporter permease subunit [KO:K01998 ]
S70_13725 livG; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01995 ]
S70_13735 livF; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01996 ]
S70_02740 d-methionine ABC transporter perisplasmic binding lipoprotein (metq-like) [KO:K02073 ]
S70_15185 metQ; DL-methionine transporter substrate-binding subunit [KO:K02073 ]
S70_00635 oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
S70_00615 oligopeptide ABC transporter ATP-binding protein OppF [KO:K10823 ]
S70_19680 antimicrobial peptide ABC transporter periplasmic binding protein SapA [KO:K19226 ]
S70_19665 antimicrobial peptide ABC transporter ATP-binding protein [KO:K19229 ]
S70_19660 antimicrobial peptide ABC system ATP-binding protein SapF [KO:K19230 ]
S70_20280 znuA; high-affinity zinc transporter periplasmic component [KO:K09815 ]
S70_20270 znuB; high-affinity zinc transporter membrane component [KO:K09816 ]
S70_19260 iron (chelated) ABC transporter periplasmic-binding protein yfea [KO:K11604 ]
S70_01145 putative ATP-binding protein of ABC transport system [KO:K16786 ] [EC:7.-.-.-]
S70_01535 outer membrane-specific lipoprotein transporter subunit LolE [KO:K09808 ]
S70_01545 outer membrane-specific lipoprotein transporter subunit LolC [KO:K09808 ]
S70_01540 lipoprotein transporter ATP-binding subunit [KO:K09810 ] [EC:7.6.2.-]
S70_06730 putative multidrug transporter membrane\ATP-binding components [KO:K18889 ]
S70_06725 putative multidrug transporter membrane\ATP-binding components [KO:K18890 ]
S70_16520 cysteine/glutathione ABC transporter membrane/ATP-binding component [KO:K16012 ]
S70_16525 cysteine/glutathione ABC transporter membrane/ATP-binding component [KO:K16013 ]
S70_16470 macrolide transporter ATP-binding/permease protein [KO:K05685 ] [EC:7.6.2.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
