KEGG   PATHWAY: pum00630
Entry
pum00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas umsongensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
pum00630  Glyoxylate and dicarboxylate metabolism
pum00630

Module
pum_M00621  Glycine cleavage system [PATH:pum00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas umsongensis [GN:pum]
Gene
HGP31_20265  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
HGP31_10010  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
HGP31_10645  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
HGP31_15525  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
HGP31_16045  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
HGP31_24760  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
HGP31_26725  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
HGP31_28740  malate synthase G [KO:K01638] [EC:2.3.3.9]
HGP31_08575  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
HGP31_09335  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
HGP31_14225  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
HGP31_16915  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
HGP31_03530  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
HGP31_12675  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
HGP31_16035  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
HGP31_19370  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
HGP31_20640  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
HGP31_20660  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
HGP31_22000  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
HGP31_22980  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
HGP31_23030  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
HGP31_22975  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
HGP31_06605  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
HGP31_17930  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
HGP31_17935  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
HGP31_17940  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
HGP31_00910  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
HGP31_10945  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
HGP31_28070  catalase [KO:K03781] [EC:1.11.1.6]
HGP31_04810  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
HGP31_26255  2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
HGP31_01020  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
HGP31_23965  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
HGP31_28420  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
HGP31_01990  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
HGP31_13260  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HGP31_13410  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HGP31_15945  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HGP31_17545  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HGP31_17745  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HGP31_18515  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
HGP31_24595  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HGP31_29800  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HGP31_29810  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HGP31_20035  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
HGP31_27105  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
HGP31_28845  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
HGP31_20030  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
HGP31_24850  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
HGP31_29905  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
HGP31_15305  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
HGP31_15310  aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
HGP31_24860  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
HGP31_29915  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
HGP31_00470  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HGP31_08610  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HGP31_14020  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HGP31_20025  gcvH; glycine cleavage system protein GcvH [KO:K02437]
HGP31_24845  gcvH; glycine cleavage system protein GcvH [KO:K02437]
HGP31_29910  gcvH; glycine cleavage system protein GcvH [KO:K02437]
HGP31_08515  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
HGP31_08510  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
HGP31_08505  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
HGP31_16610  glycerate kinase [KO:K00865] [EC:2.7.1.165]
HGP31_08500  glycerate kinase [KO:K11529] [EC:2.7.1.165]
HGP31_21520  aldA; aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
HGP31_06570  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
HGP31_05220  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
HGP31_05225  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
HGP31_14870  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
HGP31_05230  formate dehydrogenase [KO:K00124]
HGP31_14875  fdxH; formate dehydrogenase subunit beta [KO:K00124]
HGP31_05235  formate dehydrogenase subunit gamma [KO:K00127]
HGP31_14880  formate dehydrogenase subunit gamma [KO:K00127]
HGP31_03805  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
HGP31_13395  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
HGP31_25065  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
HGP31_28815  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
HGP31_12705  acetamidase [KO:K01455] [EC:3.5.1.49]
HGP31_02105  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pum00010  Glycolysis / Gluconeogenesis
pum00020  Citrate cycle (TCA cycle)
pum00030  Pentose phosphate pathway
pum00053  Ascorbate and aldarate metabolism
pum00071  Fatty acid degradation
pum00230  Purine metabolism
pum00250  Alanine, aspartate and glutamate metabolism
pum00260  Glycine, serine and threonine metabolism
pum00620  Pyruvate metabolism
pum00710  Carbon fixation by Calvin cycle
pum00750  Vitamin B6 metabolism
pum00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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