Entry
Name
ABC transporters - Raoultella sp. X13
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Raoultella sp. X13 [GN:
rao ]
Gene
DSD31_21540 thiamine/thiamine pyrophosphate ABC transporter permease ThiP [KO:K02063 ]
DSD31_15590 spermidine/putrescine ABC transporter substrate-binding protein PotD [KO:K11069 ]
DSD31_17145 spermidine/putrescine ABC transporter substrate-binding protein PotF [KO:K11073 ]
DSD31_00265 phnS; 2-aminoethylphosphonate ABC transporter substrate-binding protein [KO:K11081 ]
DSD31_00280 phnV; 2-aminoethylphosphonate ABC transport system, membrane component PhnV [KO:K11082 ]
DSD31_00275 phnU; 2-aminoethylphosphonate ABC transporter permease subunit [KO:K11083 ]
DSD31_00270 phnT; 2-aminoethylphosphonate ABC transport system ATP-binding subunit PhnT [KO:K11084 ]
DSD31_05670 proline/glycine betaine ABC transporter substrate-binding protein ProX [KO:K02002 ]
DSD31_24250 maltose/maltodextrin ABC transporter substrate-binding protein MalE [KO:K10108 ]
DSD31_24240 maltose/maltodextrin ABC transporter ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
DSD31_19660 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10111 ] [EC:7.5.2.-]
DSD31_09830 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
DSD31_02810 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
DSD31_02805 mlaE; lipid asymmetry maintenance ABC transporter permease subunit MlaE [KO:K02066 ]
DSD31_07970 galactose/glucose ABC transporter substrate-binding protein MglB [KO:K10540 ]
DSD31_01715 sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB [KO:K05813 ]
DSD31_07370 lysine/arginine/ornithine ABC transporter substrate-binding protein ArgT [KO:K10013 ]
DSD31_18195 glutamate/aspartate ABC transporter substrate-binding protein [KO:K10001 ]
DSD31_01655 branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
DSD31_01670 livk; high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK [KO:K01999 ]
DSD31_19120 branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
DSD31_12945 branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
DSD31_01675 high-affinity branched-chain amino acid ABC transporter permease LivH [KO:K01997 ]
DSD31_12935 high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998 ]
DSD31_01680 high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998 ]
DSD31_01690 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF [KO:K01996 ]
DSD31_01435 nikA; nickel ABC transporter, nickel/metallophore periplasmic binding protein [KO:K15584 ]
DSD31_21020 Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD [KO:K23227 ]
DSD31_15685 lipoprotein-releasing ABC transporter ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
DSD31_08910 yersiniabactin ABC transporter ATP-binding/permease protein YbtP [KO:K14698 ] [EC:7.-.-.-]
DSD31_08915 ybtQ; yersiniabactin ABC transporter ATP-binding/permease protein YbtQ [KO:K14699 ] [EC:7.-.-.-]
DSD31_16970 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC [KO:K16012 ]
DSD31_17000 macrolide ABC transporter ATP-binding protein/permease MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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