KEGG   PATHWAY: senq00290
Entry
senq00290                   Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Salmonella enterica subsp. enterica serovar Enteritidis EC20090531
Class
Metabolism; Amino acid metabolism
Pathway map
senq00290  Valine, leucine and isoleucine biosynthesis
senq00290

Module
senq_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:senq00290]
senq_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:senq00290]
senq_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:senq00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Salmonella enterica subsp. enterica serovar Enteritidis EC20090531 [GN:senq]
Gene
AU40_17695  threonine dehydratase [KO:K01754] [EC:4.3.1.19]
AU40_21370  threonine ammonia-lyase [KO:K01754] [EC:4.3.1.19]
AU40_00645  isopropylmalate isomerase [KO:K01703] [EC:4.2.1.33 4.2.1.35]
AU40_01795  isopropylmalate isomerase [KO:K01703] [EC:4.2.1.33 4.2.1.35]
AU40_00640  leuD; isopropylmalate isomerase [KO:K01704] [EC:4.2.1.33 4.2.1.35]
AU40_01800  3-isopropylmalate dehydratase [KO:K01704] [EC:4.2.1.33 4.2.1.35]
AU40_00650  3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
AU40_00675  acetolactate synthase 3 catalytic subunit [KO:K01652] [EC:2.2.1.6]
AU40_20770  acetolactate synthase catalytic subunit [KO:K01652] [EC:2.2.1.6]
AU40_21350  acetolactate synthase catalytic subunit [KO:K01652] [EC:2.2.1.6]
AU40_00680  ilvH; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
AU40_20765  acetolactate synthase isozyme 1 small subunit [KO:K01653] [EC:2.2.1.6]
AU40_21355  ilvM; acetolactate synthase 2 regulatory subunit [KO:K11258] [EC:2.2.1.6]
AU40_21390  ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
AU40_19285  dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
AU40_21365  dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
AU40_21360  branched chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
AU40_20060  avtA; valine--pyruvate aminotransferase [KO:K00835] [EC:2.6.1.66]
AU40_13105  aminotransferase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
AU40_00655  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
senq00260  Glycine, serine and threonine metabolism
senq00280  Valine, leucine and isoleucine degradation
senq00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

DBGET integrated database retrieval system