Entry
Name
ABC transporters - Shigella flexneri 2003036
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Shigella flexneri 2003036 [GN:
sfn ]
Gene
SFy_0343 taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
SFy_1283 alkanesulfonate transporter substrate-binding subunit [KO:K15553 ]
SFy_0080 thiamine/thiamine pyrophosphate ABC transporter, permease protein [KO:K02063 ]
SFy_1616 Spermidine/putrescine-binding periplasmic protein [KO:K11069 ]
SFy_1096 putrescine transporter subunit: membrane component of ABC superfamily [KO:K11074 ]
SFy_3841 ABC transporter protein, quaternary amine uptake transporter family [KO:K02002 ]
SFy_3684 periplasmic binding protein and sugar binding domain of the LacI family protein [KO:K23545 ]
SFy_4938 sn-glycerol-3-phosphate-binding periplasmic protein ugpB [KO:K05813 ]
SFy_4936 sn-glycerol-3-phosphate transport system permease protein ugpA [KO:K05814 ]
SFy_4935 sn-glycerol-3-phosphate transport system permease protein ugpE [KO:K05815 ]
SFy_3390 histidine-binding periplasmic protein of high-affinity histidine transport system [KO:K10014 ]
SFy_1100 arginine 3rd transport system periplasmic binding protein [KO:K09996 ]
SFy_4719 general L-amino acid transport system permease aapQ domain protein [KO:K09970 ]
SFy_4949 high-affinity amino acid transport system periplasmic binding protein [KO:K01999 ]
SFy_4940 High-affinity branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 ]
SFy_1793 Oligopeptide transport system permease protein oppB [KO:K15581 ]
SFy_1863 Peptide transport system ATP-binding protein SapD [KO:K19229 ]
SFy_1862 Peptide transport system ATP-binding protein SapF [KO:K19230 ]
SFy_1060 Glutathione transport system permease protein gsiC [KO:K13890 ]
SFy_1061 Glutathione transport system permease protein gsiD [KO:K13891 ]
SFy_0189 iron-hydroxamate transporter substrate-binding subunit [KO:K23227 ]
SFy_2676 zinc ABC transporter, periplasmic zinc-binding protein [KO:K09815 ]
SFy_2678 high-affinity zinc transporter membrane component [KO:K09816 ]
SFy_4153 putative ABC-type sulfate/molybdate transport systems, ATPase component [KO:K16787 ] [EC:7.-.-.-]
SFy_2270 Autoinducer 2 import system permease protein lsrC [KO:K10556 ]
SFy_2271 Autoinducer 2 import system permease protein lsrD [KO:K10557 ]
SFy_1612 Lipoprotein-releasing system ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
SFy_0497 multidrug transporter membrane\ATP-binding components [KO:K18890 ]
SFy_1142 cysteine/glutathione ABC transporter membrane/ATP-binding component [KO:K16012 ]
SFy_1134 Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
SFy_2474 inner membrane ABC transporter ATP-binding protein yddA [KO:K02471 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
LinkDB
All DBs