KEGG   PATHWAY: vne00061
Entry
vne00061                    Pathway                                
Name
Fatty acid biosynthesis - Virgibacillus necropolis
Class
Metabolism; Lipid metabolism
Pathway map
vne00061  Fatty acid biosynthesis
vne00061

Module
vne_M00082  Fatty acid biosynthesis, initiation [PATH:vne00061]
vne_M00083  Fatty acid biosynthesis, elongation [PATH:vne00061]
vne_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:vne00061]
Other DBs
GO: 0006633
Organism
Virgibacillus necropolis [GN:vne]
Gene
CFK40_08315  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
CFK40_09800  accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein [KO:K02160]
CFK40_11545  hypothetical protein [KO:K02160]
CFK40_09805  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
CFK40_11550  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
CFK40_08310  acetyl-CoA carboxylase, carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
CFK40_12530  fabD; [acyl-carrier-protein] S-malonyltransferase [KO:K00645] [EC:2.3.1.39]
CFK40_16640  3-oxoacyl-ACP synthase [KO:K00648] [EC:2.3.1.180]
CFK40_16635  fabF; beta-ketoacyl-[acyl-carrier-protein] synthase II [KO:K09458] [EC:2.3.1.179]
CFK40_11955  3-ketoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CFK40_05995  oxidoreductase [KO:K00059] [EC:1.1.1.100]
CFK40_15230  3-ketoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CFK40_06235  3-oxoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CFK40_12525  beta-ketoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CFK40_03820  3-oxoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CFK40_03860  3-oxoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CFK40_05090  short-chain dehydrogenase [KO:K00059] [EC:1.1.1.100]
CFK40_14330  beta-ketoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CFK40_15515  short-chain dehydrogenase [KO:K00059] [EC:1.1.1.100]
CFK40_05290  3-ketoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
CFK40_03255  fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
CFK40_06530  enoyl-[acyl-carrier-protein] reductase [KO:K00208] [EC:1.3.1.9 1.3.1.10]
CFK40_18300  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
CFK40_16835  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
CFK40_14350  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
vne00020  Citrate cycle (TCA cycle)
vne00071  Fatty acid degradation
vne00410  beta-Alanine metabolism
vne00561  Glycerolipid metabolism
vne00564  Glycerophospholipid metabolism
vne00620  Pyruvate metabolism
vne00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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