Entry
Name
ABC transporters - Vibrio ziniensis
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Vibrio ziniensis [GN:
vzi ]
Gene
G5S32_01635 thiP; thiamine/thiamine pyrophosphate ABC transporter permease ThiP [KO:K02063 ]
G5S32_03015 spermidine/putrescine ABC transporter substrate-binding protein [KO:K11069 ]
G5S32_16945 spermidine/putrescine ABC transporter substrate-binding protein [KO:K11069 ]
G5S32_19055 proX; glycine betaine/L-proline ABC transporter substrate-binding protein ProX [KO:K02002 ]
G5S32_19060 proW; glycine betaine/L-proline ABC transporter permease ProW [KO:K02001 ]
G5S32_18085 malE; maltose/maltodextrin ABC transporter substrate-binding protein MalE [KO:K10108 ]
G5S32_18080 malK; maltose/maltodextrin ABC transporter ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
G5S32_19235 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10195 ]
G5S32_01725 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
G5S32_01720 mlaE; lipid asymmetry maintenance ABC transporter permease subunit MlaE [KO:K02066 ]
G5S32_07925 mglB; galactose/glucose ABC transporter substrate-binding protein MglB [KO:K10540 ]
G5S32_07915 mglC; galactose/methyl galactoside ABC transporter permease MglC [KO:K10541 ]
G5S32_03165 pstS; phosphate ABC transporter substrate-binding protein PstS family protein [KO:K02040 ]
G5S32_12515 fepB; Fe2+-enterobactin ABC transporter substrate-binding protein [KO:K23185 ]
G5S32_11870 btuF; vitamin B12 ABC transporter substrate-binding protein BtuF [KO:K06858 ]
G5S32_07580 energy-coupling factor ABC transporter substrate-binding protein [KO:K02009 ]
G5S32_04685 lolC; lipoprotein-releasing ABC transporter permease subunit LolC [KO:K09808 ]
G5S32_04695 lolE; lipoprotein-releasing ABC transporter permease subunit LolE [KO:K09808 ]
G5S32_04690 lolD; lipoprotein-releasing ABC transporter ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
G5S32_05755 cydC; cysteine/glutathione ABC transporter ATP-binding protein/permease CydC [KO:K16012 ]
G5S32_05760 cydD; cysteine/glutathione ABC transporter permease/ATP-binding protein CydD [KO:K16013 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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