Entry
Name
ABC transporters - Yersinia kristensenii
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Yersinia kristensenii [GN:
yki ]
Gene
HRD70_08130 thiP; thiamine/thiamine pyrophosphate ABC transporter permease ThiP [KO:K02063 ]
HRD70_12345 potF; spermidine/putrescine ABC transporter substrate-binding protein PotF [KO:K11073 ]
HRD70_09365 proX; glycine betaine/L-proline ABC transporter substrate-binding protein ProX [KO:K02002 ]
HRD70_09370 proW; glycine betaine/L-proline ABC transporter permease ProW [KO:K02001 ]
HRD70_02535 malE; maltose/maltodextrin ABC transporter substrate-binding protein MalE [KO:K10108 ]
HRD70_00890 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10111 ] [EC:7.5.2.-]
HRD70_02530 malK; maltose/maltodextrin ABC transporter ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
HRD70_02050 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
HRD70_02055 mlaE; lipid asymmetry maintenance ABC transporter permease subunit MlaE [KO:K02066 ]
HRD70_19040 mglB; galactose/glucose ABC transporter substrate-binding protein MglB [KO:K10540 ]
HRD70_19030 mglC; galactose/methyl galactoside ABC transporter permease MglC [KO:K10541 ]
HRD70_05770 ugpB; sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB [KO:K05813 ]
HRD70_04405 pstS; phosphate ABC transporter substrate-binding protein PstS [KO:K02040 ]
HRD70_11515 hisJ; histidine ABC transporter substrate-binding protein HisJ [KO:K10014 ]
HRD70_19175 glnH; glutamine ABC transporter substrate-binding protein GlnH [KO:K10036 ]
HRD70_05715 branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
HRD70_05720 livH; high-affinity branched-chain amino acid ABC transporter permease LivH [KO:K01997 ]
HRD70_05725 high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998 ]
HRD70_05730 livG; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG [KO:K01995 ]
HRD70_05735 livF; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF [KO:K01996 ]
HRD70_16020 oppA; oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
HRD70_16000 oppF; murein tripeptide/oligopeptide ABC transporter ATP binding protein OppF [KO:K10823 ]
HRD70_01295 fepB; Fe2+-enterobactin ABC transporter substrate-binding protein [KO:K23185 ]
HRD70_08555 fhuD; Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD [KO:K23227 ]
HRD70_08595 btuF; vitamin B12 ABC transporter substrate-binding protein BtuF [KO:K06858 ]
HRD70_14550 yfeA; iron/manganese ABC transporter substrate-binding protein YfeA [KO:K11604 ]
HRD70_14545 yfeB; iron/manganese ABC transporter ATP-binding protein YfeB [KO:K11607 ]
HRD70_18540 energy-coupling factor ABC transporter substrate-binding protein [KO:K02009 ]
HRD70_07585 lsrB; autoinducer 2 ABC transporter substrate-binding protein LsrB [KO:K10555 ]
HRD70_13475 lolC; lipoprotein-releasing ABC transporter permease subunit LolC [KO:K09808 ]
HRD70_13485 lolE; lipoprotein-releasing ABC transporter permease subunit LolE [KO:K09808 ]
HRD70_13480 lolD; lipoprotein-releasing ABC transporter ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
HRD70_20870 SmdA family multidrug ABC transporter permease/ATP-binding protein [KO:K18889 ]
HRD70_20865 SmdB family multidrug efflux ABC transporter permease/ATP-binding protein [KO:K18890 ]
HRD70_12495 cydC; cysteine/glutathione ABC transporter ATP-binding protein/permease CydC [KO:K16012 ]
HRD70_12500 cydD; cysteine/glutathione ABC transporter permease/ATP-binding protein CydD [KO:K16013 ]
HRD70_12465 macB; macrolide ABC transporter ATP-binding protein/permease MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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