PATHWAY: yps02010 Help
Entry
Name
ABC transporters - Yersinia pseudotuberculosis IP 32953 (serotype I)
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Yersinia pseudotuberculosis IP 32953 (serotype I) [GN:
yps ]
Gene
YPTB2735 cysP; ABC transporter, periplasmic thiosulfate-binding protein CysP [KO:K02048 ]
YPTB0075 sbp1; ABC type periplasmic sulfate-binding protein [KO:K23163 ]
YPTB2734 cysT; ABC sulfate transporter, permease subunit CysT [KO:K02046 ]
YPTB2733 cysW; ABC sulfate transporter, permease subunit CysW [KO:K02047 ]
YPTB3722 tauA; ABC transporter, periplasmic taurine-binding protein [KO:K15551 ]
YPTB3605 ssuA; ABC transporter, aliphatic sulfonates binding protein [KO:K15553 ]
YPTB3603 ssuC; ABC aliphatic sulfonates transporter, permease subunit [KO:K15554 ]
YPTB0076 possible ABC transporter, periplasmic molybdate binding protein [KO:K02020 ]
YPTB1176 modA; ABC transporter, periplasmic molybdate-binding protein ModA [KO:K02020 ]
YPTB1177 modB; ABC molybdenum transporter, permease subunit ModB [KO:K02018 ]
YPTB1173 modF; ABC molybdenum transporter, ATP-binding subunit modF [KO:K05776 ]
YPTB2682 sfuA; ABC transporter, periplasmic iron(III)-binding protein [KO:K02012 ]
YPTB2772 putative ABC transporter, periplasmmic iron binding protein [KO:K02012 ]
YPTB2683 sfuB; ABC iron(III) transporter, fused permease domains [KO:K02011 ]
YPTB2771 putative ABC iron transporter, fused permease domains [KO:K02011 ]
YPTB0663 tbpA; ABC transporter, periplasmic thiamine binding protein tbpA [KO:K02064 ]
YPTB0662 thiP; ABC thiamine transporter, fused permease domains, thiP [KO:K02063 ]
YPTB1361 potF; ABC type periplasmic putrescine/spermidine binding protein, potF [KO:K11073 ]
YPTB1363 potH; ABC type putrescine/spermidine transporter, permease protein potH [KO:K11075 ]
YPTB2961 proX; ABC transporter, periplasmic proline/glycine/betaine-binding protein proX [KO:K02002 ]
YPTB2960 proW; ABC glycine/betaine/L-proline transporter, permease subunit proW [KO:K02001 ]
YPTB2959 proV; ABC glycine/betaine/L-proline transporter, ATP-binding subunit proV [KO:K02000 ] [EC:7.6.2.9 ]
YPTB1236 ABC type periplasmic choline/glycine/betaine binding protein [KO:K05845 ]
YPTB1237 ABC type choline/glycine/betaine transporter, permease subunit [KO:K05846 ]
YPTB1239 ABC type choline/glycine/betaine transporter, permease subunit [KO:K05846 ]
YPTB3645 malE; ABC transporter, periplasmic maltose-binding protein malE [KO:K10108 ]
YPTB3646 malF; ABC maltose/maltodextrin transporter, permease subunit malF [KO:K10109 ]
YPTB3647 malG; ABC maltose transporter, permease subunit malG [KO:K10110 ]
YPTB3643 malK; ABC maltose/maltodextrin transporter, ATP-binding subunit malK [KO:K10111 ] [EC:7.5.2.-]
YPTB2521 mtlK; putative ABC type sugar transporter, ATP-binding subunit [KO:K10111 ] [EC:7.5.2.-]
YPTB3102 ABC sugar transporter, ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
YPTB1916 ABC sugar transporter, ATP binding subunit [KO:K10111 ] [EC:7.5.2.-]
YPTB3446 ABC sugar transporter, ATP-binding subunit [KO:K10112 ] [EC:7.5.2.-]
YPTB0504 putative sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
YPTB3101 ABC type periplasmic sugar(maltose)-binding protein [KO:K15770 ]
YPTB2362 putative ABC type periplasmic sugar-binding protein [KO:K10192 ]
YPTB3518 yrbE; ABC transporter, permease subunit, toluene tolerance protein [KO:K02066 ]
YPTB3519 yrbF; ABC transporter, ATP-binding subunit, toluene tolerance protein [KO:K02065 ]
YPTB2537 ABC transporter, periplasmic sugar (possibly sorbitol) binding protein [KO:K10439 ]
YPTB3231 Putative sugar ABC transporter periplasmic binding protein [KO:K10439 ]
YPTB3805 ABC transporter, periplasmic ribose binding protein [KO:K10439 ]
YPTB2535 putative ABC sugar (sorbitol) transporter, permease subunit [KO:K10440 ]
YPTB2174 araF; ABC transporter, periplasmic L-arabinose-binding protein araF [KO:K10537 ]
YPTB2176 araH; ABC L-arabinose transporter, permease subunit araH [KO:K10538 ]
YPTB0127 ABC transporter, periplasmic ribose/sugar binding protein [KO:K23508 ]
YPTB1522 mglB; ABC transporter, perplasmic galactose-binding protein [KO:K10540 ]
YPTB1524 mglC; ABC galactoside transporter, permease subunit mglC [KO:K10541 ]
YPTB3890 ABC transporter, periplasmic xylose binding protein [KO:K10543 ]
YPTB3888 xylH; ABC xylose transporter, fused permease domains [KO:K10544 ]
YPTB2204 putative ABC transporter, periplasmic ribose/sugar-binding protein [KO:K17202 ]
YPTB0812 ABC transporter, periplasmic sugar binding protein [KO:K17202 ]
YPTB2206 putative ABC sugar/ribose transporter, fused ATP-binding domains [KO:K17204 ]
YPTB3105 ABC transporter, periplasmic sugar-binding protein [KO:K17205 ]
YPTB1074 putative ABC type sugar-binding periplasmic protein [KO:K17208 ]
YPTB1075 ABC type sugar transporter with fused ATP-binding domains [KO:K17210 ]
YPTB0238 ugpB; sn-glycerol-3-phosphate ABC type periplasmic binding protein [KO:K05813 ]
YPTB0239 ugpA; sn-glycerol-3-phosphate ABC type transport system, permease protein [KO:K05814 ]
YPTB0240 ugpE; sn-glycerol-3-phosphate ABC type transport system, permease protein [KO:K05815 ]
YPTB0241 ugpC; sn-glycerol-3-phosphate ABC type transport system, ATP-binding protein [KO:K05816 ] [EC:7.6.2.10 ]
YPTB0919 pstS; ABC superfamily (peri_bind) high-affinity phosphate transporter [KO:K02040 ]
YPTB3963 pstS; ABC transporter, periplasmic phosphate-binding protein pstS [KO:K02040 ]
YPTB2801 pstC; putative ABC phosphate transporter, permease subunit [KO:K02037 ]
YPTB3962 pstC; ABC phosphate transporter, permease subunit pstS [KO:K02037 ]
YPTB2800 pstA; putative ABC phosphate transporter, permease subunit [KO:K02038 ]
YPTB3961 pstA; ABC phosphate transporter, permease subunit pstA [KO:K02038 ]
YPTB1224 phnD; ABC periplasmic phosphonate binding protein, phnD [KO:K02044 ]
YPTB2608 hisM; ABC histidine transporter, permease subunit HisM [KO:K10015 ]
YPTB2609 hisQ; ABC histidine transporter, permease subunit HisQ [KO:K10016 ]
YPTB2610 hisJ; ABC tranporter, periplasmic histidine-binding protein hisJ [KO:K10014 ]
YPTB2548 glnH; ABC tranporter, periplasmic glutamine-binding protein glnH [KO:K10036 ]
YPTB2549 glnP; ABC glutamine transporter, permease subunit glnP [KO:K10037 ]
YPTB1367 artJ; ABC transporter, periplasmic arginine binding protein artJ [KO:K09996 ]
YPTB1377 artI; ABC transporter, periplasmic arginine-binding protein artI [KO:K09997 ]
YPTB1375 artM; ABC arginine transporter, permease subunit artM [KO:K09998 ]
YPTB1376 artQ; ABC arginine transporter, permease subunit artQ [KO:K09999 ]
YPTB1108 ybeJ; ABC transporter, periplasmic glutamate/aspatate binding protein [KO:K10001 ]
YPTB1106 gltK; ABC glutamate/aspartate transporter, permease subunit gltK [KO:K10002 ]
YPTB1107 gltJ; ABC glutamate/aspartate transporter, permease subunit gltJ [KO:K10003 ]
YPTB1718 fliY; putative cystine-binding periplasmic protein [KO:K02424 ]
YPTB1719 yecS; putative amino-acid ABC transporter (permease) [KO:K10009 ]
YPTB0226 livK; ABC type periplasmic branched-chain amino acid-binding protein [KO:K01999 ]
YPTB0227 livH; ABC type branched-chain aa transport system, permease [KO:K01997 ]
YPTB0228 livM; ABC type branched-chain aa transport system, permease [KO:K01998 ]
YPTB0229 livG; ABC type branched-chain aa transport, ATP-binding protein [KO:K01995 ]
YPTB0230 livF; ABC type branched-chain aa transport, ATP-binding protein [KO:K01996 ]
YPTB2975 possible ABC transporter, periplasmic solute binding protein [KO:K02073 ]
YPTB1348 possible ABC type periplasmic substrate binding protein [KO:K02073 ]
YPTB1228 ABC type periplasmic branched chain aa binding protein [KO:K11959 ]
YPTB1229 ABC type branched-chain amino acid transporter, permease protein [KO:K11960 ]
YPTB1230 ABC type branched-chain amino acid transporter, permease protein [KO:K11961 ]
YPTB1231 ABC branch chain aa transporter, ATP-binding subunit [KO:K11962 ]
YPTB1232 ABC branched chain aa transporter, ATP-binding subunit [KO:K11963 ]
YPTB1186 putative ABC branched chain amino acid transporter, ATP binding subunit [KO:K11963 ]
YPTB2105 oppA; ABC transporter, periplasmic oligopeptide-binding protein oppA [KO:K15580 ]
YPTB2258 mppA; putative ABC transporter, periplasmic murein peptide-binding protein [KO:K15580 ]
YPTB2106 oppB; ABC oligopeptide transporter, permease subunit oppB [KO:K15581 ]
YPTB2107 oppC; ABC oligopeptide transporter, permease subunit oppC [KO:K15582 ]
YPTB2108 oppD; ABC oligopeptide transporter, ATP-binding subunit oppD [KO:K15583 ]
YPTB2109 oppF; ABC oligopeptide transporter, ATP-binding subunit oppF [KO:K10823 ]
YPTB3842 dppA; ABC transporter, periplasmic dipeptide binding protein [KO:K12368 ]
YPTB3841 dppB; ABC dipeptide transporter, permease subunit [KO:K12369 ]
YPTB3840 dppC; ABC dipeptide transporter, permease subunit [KO:K12370 ]
YPTB3839 dppD; ABC dipeptide transporter, ATP-binding subunit [KO:K12371 ]
YPTB3838 dppF; ABC dipeptide transporter, ATP-binding subunit [KO:K12372 ]
YPTB2272 sapA; ABC transporter, periplasmic peptide binding protein sapA [KO:K19226 ]
YPTB2273 sapB; ABC peptide transporter, permease subunit sapB [KO:K19227 ]
YPTB2274 sapC; ABC peptide transporter, permease subunit sapC [KO:K19228 ]
YPTB2275 sapD; ABC peptide transporter, ATP-binding subunit sapD [KO:K19229 ]
YPTB2276 sapF; ABC peptide transporter, ATP-binding subunit sapF [KO:K19230 ]
YPTB1307 yejA; putative ABC transporter, oligo-dipeptide/nickel binding protein [KO:K13893 ]
YPTB1306 yejB; ABC oligo-dipeptide/nickel transporter, permease subunit [KO:K13894 ]
YPTB1305 yejE; ABC oligo-dipeptide/nickel transporter, permease subunit [KO:K13895 ]
YPTB1304 yejF; ABC oligo-dipeptide/nickel transporter, fused ATP-binding domains [KO:K13896 ]
YPTB3360 fepB; ABC transporter, periplasmic ferric enterobactin binding protein [KO:K23185 ]
YPTB1548 putative ABC transporter, periplasmic iron-siderophore binding protein [KO:K25286 ]
YPTB1547 putative ABC iron-siderophore transporter, permease subunit [KO:K23186 ]
YPTB1546 putative ABC iron-siderophore transporter, permease subunit [KO:K23187 ]
YPTB0740 fhuD; ABC type hydroxamate-dependent iron uptake ATP binding protein [KO:K23227 ]
YPTB0741 fhuB; ABC type hydroxamate-dependent iron uptake, with duplicated permease domains [KO:K23228 ]
YPTB0746 yadT; putative ABC transporter, periplasmic cobalamin binding protein [KO:K06858 ]
YPTB2333 btuC; puative ABC vitamin B12 transporter, permease subunit btuC [KO:K06073 ]
YPTB2044 znuA; ABC high-affinity zinc uptake transporter, periplasmic binding protein [KO:K09815 ]
YPTB2042 znuB; ABC high-affinity zinc uptake transporter, permease subunit znuB [KO:K09816 ]
YPTB2347 yfeA; ABC transporter, periplasmic iron siderophore-binding protein YfeA [KO:K11604 ]
YPTB2349 yfeC; ABC chelated iron transporter, permease subunit yfeC [KO:K11605 ]
YPTB2350 yfeD; ABC chelated iron transporter, permease subunit yfeD [KO:K11606 ]
YPTB2348 yfeB; ABC chelated iron transporter, ATP-binding subunit yfeB [KO:K11607 ]
YPTB0549 ABC transporter, perplasmic sugar binding protein [KO:K10555 ]
YPTB0552 ego; ABC sugar transporter, fused ATP binding domains [KO:K10558 ]
YPTB2442 lolC; ABC transporter/lipoprotein releasing system, permease subunit lolC [KO:K09808 ]
YPTB2440 lolE; ABC tranporter/lipoprotein releasing system, permease subunit lolE [KO:K09808 ]
YPTB2441 lolD; ABC transporter/lipoprotein releasing system, ATP-binding subunit lolD [KO:K09810 ] [EC:7.6.2.-]
YPTB2647 ccmC; putative ABC type heme exporter, permease subunit ccmC [KO:K02195 ]
YPTB2648 ccmB; ABC type heme exporter, permease subunit ccmB [KO:K02194 ]
YPTB1598 ybtP; lipoprotein inner membrane ABC-transporter [KO:K14698 ] [EC:7.-.-.-]
YPTB3291 putative ABC iron siderophore transporter, fused permease and ATPase domains [KO:K14698 ] [EC:7.-.-.-]
YPTB1599 ybtQ; inner membrane ABC-transporter YbtQ [KO:K14699 ] [EC:7.-.-.-]
YPTB3290 putative ABC iron siderophore transporter, fused permease and ATPase domains. [KO:K14699 ] [EC:7.-.-.-]
YPTB1420 msbA; ABC phospholipid/LPS/lipidA transporter MsbA, fused permease and ATP-binding domains [KO:K11085 ] [EC:7.5.2.6 ]
YPTB0971 mdlA; ABC type drug efflux transporter, fused ATP binding and permease domains [KO:K18889 ]
YPTB0972 mdlB; ABC type drug efflux transporter, fused ATP binding and permease domains [KO:K18890 ]
YPTB0090 ABC transporter, multidrug efflux pump, fused permease and ATPase domains [KO:K13409 ]
YPTB1082 putative ABC transport protein with fused ATP binding and permease domains [KO:K24821 ]
YPTB0115 ABC transporter protein, fused permease and ATP binding domains [KO:K12536 ]
YPTB1397 cydC; putative ABC cytochrome efflux transporter, fused ATP-binding and permease domains [KO:K16012 ]
YPTB1398 cydD; putative ABC cytochrome efflux transporter, fused ATP-binding and permease domains [KO:K16013 ]
YPTB1391 putative ABC transporter with fused permease and ATP-binding domains [KO:K05685 ] [EC:7.6.2.-]
YPTB2721 ABC transporter(efflux), fused permease and ATP-binding domains [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
LinkDB
All DBs