KEGG   PATHWAY: psuu00290
Entry
psuu00290                   Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Phytohabitans suffuscus
Class
Metabolism; Amino acid metabolism
Pathway map
psuu00290  Valine, leucine and isoleucine biosynthesis
psuu00290

Module
psuu_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:psuu00290]
psuu_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:psuu00290]
psuu_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:psuu00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Phytohabitans suffuscus [GN:psuu]
Gene
Psuf_003700  ilvB_1; acetolactate synthase I/II/III large subunit [KO:K01652] [EC:2.2.1.6]
Psuf_018590  [KO:K01652] [EC:2.2.1.6]
Psuf_024330  ilvA_1; threonine ammonia-lyase [KO:K01754] [EC:4.3.1.19]
Psuf_030280  leuA_1; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Psuf_035990  ilvA_2; serine/threonine dehydratase [KO:K01754] [EC:4.3.1.19]
Psuf_047970  ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
Psuf_047990  ilvB_3; acetolactate synthase [KO:K01652] [EC:2.2.1.6]
Psuf_048000  ilvH; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
Psuf_048010  ilvC; ketol-acid reductoisomerase (NADP(+)) [KO:K00053] [EC:1.1.1.86]
Psuf_048070  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
Psuf_048080  [KO:K00826] [EC:2.6.1.42]
Psuf_048110  leuA_2; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Psuf_048360  [KO:K01703] [EC:4.2.1.33 4.2.1.35]
Psuf_048380  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
Psuf_067440  ilvB_4; acetolactate synthase [KO:K01652] [EC:2.2.1.6]
Psuf_076160  [KO:K01652] [EC:2.2.1.6]
Psuf_085270  ilvE2; aminotransferase class IV [KO:K00826] [EC:2.6.1.42]
Psuf_087760  [KO:K01652] [EC:2.2.1.6]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
psuu00260  Glycine, serine and threonine metabolism
psuu00280  Valine, leucine and isoleucine degradation
psuu00620  Pyruvate metabolism
KO pathway
ko00290   

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