Pan troglodytes (chimpanzee): 450428
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Entry
450428 CDS
T01005
Symbol
ALOX5
Name
(RefSeq) polyunsaturated fatty acid 5-lipoxygenase
KO
K00461
arachidonate 5-lipoxygenase [EC:
1.13.11.34
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00590
Arachidonic acid metabolism
ptr01100
Metabolic pathways
ptr04148
Efferocytosis
ptr04664
Fc epsilon RI signaling pathway
ptr04726
Serotonergic synapse
ptr04913
Ovarian steroidogenesis
ptr05145
Toxoplasmosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
450428 (ALOX5)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
450428 (ALOX5)
09150 Organismal Systems
09151 Immune system
04664 Fc epsilon RI signaling pathway
450428 (ALOX5)
09152 Endocrine system
04913 Ovarian steroidogenesis
450428 (ALOX5)
09156 Nervous system
04726 Serotonergic synapse
450428 (ALOX5)
09160 Human Diseases
09174 Infectious disease: parasitic
05145 Toxoplasmosis
450428 (ALOX5)
Enzymes [BR:
ptr01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.34 arachidonate 5-lipoxygenase
450428 (ALOX5)
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Paralog
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
450428
NCBI-ProteinID:
XP_016773660
Ensembl:
ENSPTRG00000002458
VGNC:
51965
UniProt:
A0A2J8IP81
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Position
8:58243036..58313203
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AA seq
674 aa
AA seq
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MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE
ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA
RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG
CNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP
CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF
HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG
LFDKANATGGGGHVQMVQRAMKDLTYTSLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE
AIRTFTAEVVDIYYESDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL
TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW
HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPY
YYLSPDRIPNSVAI
NT seq
2025 nt
NT seq
+upstream
nt +downstream
nt
atgccctcctacacggtcaccgtggccactggcagccagtggttcgccggcactgacgac
tacatctacctcagcctcgtgggctcggcgggctgcagcgagaagcacctgctggacaag
cccttctacaacgacttcgagcgtggcgcggtggattcgtatgacgtgactgtggacgag
gaactgggcgagatccagctggtcagaatcgagaagcgcaagtactggctgaatgacgac
tggtacctgaagtacatcacgctgaagacgccccacggggactacatcgagttcccctgc
taccgctggatcaccggcgatgtcgaggttgtcctgagggatggacgcgcaaagttggcc
cgagatgaccaaattcacattctcaagcaacaccgacgtaaagaactggaaacacggcaa
aaacaatatcgatggatggagtggaaccctggcttccccttgagcatcgatgccaaatgc
cacaaggatttaccccgtgatatccagtttgatagtgaaaaaggagtggactttgttctg
aattactccaaagcgatggagaacctgttcatcaaccgcttcatgcatatgttccagtct
tcttggaatgacttcgccgactttgagaaaatctttgtcaagatcagcaacactatttct
gagcgggtcatgaatcactggcaggaagacctgatgtttggctaccagttcctgaatggc
tgcaaccctgtgttgatccggcgctgcacagagctgcccgagaagctcccggtgaccacg
gagatggtagagtgcagcctggagcggcagctcagcttggagcaggaggtccagcaaggg
aacattttcatcgtggactttgagctgctggatggcatcgatgccaacaaaacagacccc
tgcacactccagttcctggccgctcccatctgcttgctgtataagaacctggccaacaag
attgtccccattgccatccagctcaaccaaatcccgggagatgagaaccctattttcctc
ccttcggatgcaaaatacgactggcttttggccaaaatctgggtgcgttccagtgacttc
cacgtccaccagaccatcacccaccttctgcgaacacatctggtgtctgaggtttttggc
attgcaatgtaccgccagctgcctgctgtgcaccccattttcaagctgctggtggcacac
gtgagattcaccatcgcaatcaacaccaaggcccgtgagcagctcatctgcgagtgtggc
ctctttgacaaggccaacgccacagggggcggtgggcacgtgcagatggtgcagagggcc
atgaaggacctgacctacacctccctgtgctttcccgaggccatcaaggcccggggcatg
gagagcaaagaagacatcccctactacttctaccgggacgacgggctcctggtgtgggaa
gccatcaggacgttcacggccgaggtggtagacatctactacgagagcgaccaggtggtg
gaggaggacccggagctgcaggacttcgtgaacgatgtctacgtgtacggcatgcggggc
cgcaagtcctcaggcttccccaagtcggtcaagagccgggagcagctgtcggagtacctg
accgtggtgatcttcaccgcctccgcccagcacgccgcggtcaacttcggccagtacgac
tggtgctcctggatccccaatgcgcccccaaccatgcgagccccgccgccgactgccaag
ggcgtggtgaccattgagcagatcgtggacacgctgcccgaccgcggccgctcctgctgg
catctgggtgcagtgtgggcgctgagccagttccaggaaaacgagctgttcctgggcatg
tacccagaagagcattttatcgagaagcctgtgaaggaggccatggcccgattccgcaag
aacctcgaggccattgtcagcgtgattgctgagcgcaacaagaagaagcagctgccatat
tactacttgtccccagaccggattccgaacagtgtggccatctga
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