Pan troglodytes (chimpanzee): 459018
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Entry
459018 CDS
T01005
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X2
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04148
Efferocytosis
ptr04330
Notch signaling pathway
ptr04668
TNF signaling pathway
ptr05010
Alzheimer disease
ptr05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
459018 (ADAM17)
04668 TNF signaling pathway
459018 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
459018 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
459018 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
459018 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ptr01002
]
459018 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ptr04090
]
459018 (ADAM17)
Enzymes [BR:
ptr01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
459018 (ADAM17)
Peptidases and inhibitors [BR:
ptr01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
459018 (ADAM17)
CD molecules [BR:
ptr04090
]
Proteins
459018 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_5
Reprolysin_2
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Motif
Other DBs
NCBI-GeneID:
459018
NCBI-ProteinID:
XP_016802294
Ensembl:
ENSPTRG00000011640
VGNC:
6
LinkDB
All DBs
Position
12:113321860..113389267
Genome browser
AA seq
685 aa
AA seq
DB search
MTRASAPTRDSPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGL
VDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVD
DIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLE
QFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIY
LNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIA
VSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNND
TCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPG
NAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQ
KNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVF
SLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRL
QPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHP
VTRSEKAASFKLQRQNRVDSKETEC
NT seq
2058 nt
NT seq
+upstream
nt +downstream
nt
atgacccgggcttcggcccccaccagagactcgccactttggagatttgttaatgatacc
aaagacaaaagaatgttagtttataaatctgaagatatcaagaatgtttcacgtttgcag
tctccaaaagtgtgtggttatttaaaagtggataatgaagagttgctcccaaaagggtta
gtagacagagaaccacctgaagagcttgttcatcgagtgaaaagaagagctgacccagat
cccatgaagaacacgtgtaaattattggtggtagcagatcatcgcttctacagatacatg
ggcagaggggaagagagtacaactacaaattacttaatagagctaattgacagagttgat
gacatctatcggaacacttcatgggataatgcgggttttaaaggctatggaatacagata
gagcagattcgcattctcaagtctccacaagaggtaaaacctggtgaaaagcactacaac
atggcaaaaagttacccaaatgaagaaaaggatgcttgggatgtgaagatgttgctagag
caatttagctttgatatagctgaggaagcatctaaagtttgcttggcacaccttttcaca
taccaagattttgatatgggaactcttggattagcttatgttggctctcccagagcaaac
agccatggaggtgtttgtccaaaggcttattatagcccagttgggaagaaaaatatctat
ttgaatagtggtttgacgagcacaaagaattatggtaaaaccatccttacaaaggaagct
gacctggttacaactcatgaattgggacataattttggagcagaacatgatccggatggt
ctagcagaatgtgccccgaatgaagaccagggagggaaatatgtcatgtatcccatagct
gtgagtggcgatcacgagaacaataagatgttttcaaactgcagtaaacaatcaatctat
aagaccattgaaagtaaggcccaggagtgttttcaagaacgcagcaataaagtttgtggg
aactcgagggtagatgaaggagaagagtgcgatcctggcatcatgtatctgaacaacgac
acctgctgcaacagcgactgcacgttgaaggaaggtgtccagtgcagtgacaggaacagt
ccttgctgtaaaaactgtcagtttgagactgcccagaagaagtgccaggaggcgattaat
gctacttgcaaaggcgtgtcctactgcacaggtaatagcagtgagtgcccgcctccggga
aatgctgaagatgacactgtttgcttggatcttggcaagtgtaaggatgggaaatgcatc
cctttctgcgagagggaacagcagctggagtcctgtgcatgtaatgaaactgacaactcc
tgcaaggtgtgctgcagggacctttccggccgctgtgtgccctacgtcgatgctgaacaa
aagaacttatttttgaggaaaggaaagccctgtacagtaggattttgtgacatgaatggc
aaatgtgagaaacgagtacaggatgtaattgaacgattttgggatttcattgaccagctg
agcatcaatacttttggaaagtttttagcagacaacatcgttgggtctgtcctggttttc
tccttgatattttggattcctttcagcattcttgtccattgtgtggataagaaattggat
aaacagtatgaatctctgtctctgtttcaccccagtaacgtcgaaatgctgagcagcatg
gattctgcatcggttcgcattatcaaaccctttcctgcgccccagactccaggccgcctg
cagcctgcccctgtgatcccttcggcgccagcagctccgaaactggaccaccagagaatg
gacaccatccaggaagaccccagcacagactcacatatggacgaggatgggtttgagaag
gaccccttcccaaatagcagcacagccgccaagtcatttgaggatctcacggaccatccg
gtcaccagaagtgaaaaggctgcctcctttaaactgcagcgtcagaatcgtgttgacagc
aaagaaacagagtgctag
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