Pan troglodytes (chimpanzee): 461669 Help Entry 461669            CDS       T01005                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X2   KO K02187   caspase 3 [EC:3.4.22.56] Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr01524   Platinum drug resistance ptr04010   MAPK signaling pathway ptr04115   p53 signaling pathway ptr04148   Efferocytosis ptr04210   Apoptosis ptr04215   Apoptosis - multiple species ptr04623   Cytosolic DNA-sensing pathway ptr04650   Natural killer cell mediated cytotoxicity ptr04657   IL-17 signaling pathway ptr04668   TNF signaling pathway ptr04726   Serotonergic synapse ptr04932   Non-alcoholic fatty liver disease ptr04933   AGE-RAGE signaling pathway in diabetic complications ptr04936   Alcoholic liver disease ptr05010   Alzheimer disease ptr05012   Parkinson disease ptr05014   Amyotrophic lateral sclerosis ptr05016   Huntington disease ptr05020   Prion disease ptr05022   Pathways of neurodegeneration - multiple diseases ptr05132   Salmonella infection ptr05133   Pertussis ptr05134   Legionellosis ptr05145   Toxoplasmosis ptr05146   Amoebiasis ptr05152   Tuberculosis ptr05160   Hepatitis C ptr05161   Hepatitis B ptr05162   Measles ptr05163   Human cytomegalovirus infection ptr05164   Influenza A ptr05165   Human papillomavirus infection ptr05167   Kaposi sarcoma-associated herpesvirus infection ptr05168   Herpes simplex virus 1 infection ptr05169   Epstein-Barr virus infection ptr05170   Human immunodeficiency virus 1 infection ptr05200   Pathways in cancer ptr05203   Viral carcinogenesis ptr05205   Proteoglycans in cancer ptr05206   MicroRNAs in cancer ptr05210   Colorectal cancer ptr05222   Small cell lung cancer ptr05416   Viral myocarditis ptr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ptr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     461669 (CASP3)    04668 TNF signaling pathway     461669 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     461669 (CASP3)   09143 Cell growth and death    04210 Apoptosis     461669 (CASP3)    04215 Apoptosis - multiple species     461669 (CASP3)    04115 p53 signaling pathway     461669 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     461669 (CASP3)    04650 Natural killer cell mediated cytotoxicity     461669 (CASP3)    04657 IL-17 signaling pathway     461669 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     461669 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     461669 (CASP3)    05206 MicroRNAs in cancer     461669 (CASP3)    05205 Proteoglycans in cancer     461669 (CASP3)    05203 Viral carcinogenesis     461669 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     461669 (CASP3)    05222 Small cell lung cancer     461669 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     461669 (CASP3)    05161 Hepatitis B     461669 (CASP3)    05160 Hepatitis C     461669 (CASP3)    05164 Influenza A     461669 (CASP3)    05162 Measles     461669 (CASP3)    05168 Herpes simplex virus 1 infection     461669 (CASP3)    05163 Human cytomegalovirus infection     461669 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     461669 (CASP3)    05169 Epstein-Barr virus infection     461669 (CASP3)    05165 Human papillomavirus infection     461669 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     461669 (CASP3)    05133 Pertussis     461669 (CASP3)    05134 Legionellosis     461669 (CASP3)    05152 Tuberculosis     461669 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     461669 (CASP3)    05145 Toxoplasmosis     461669 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     461669 (CASP3)    05012 Parkinson disease     461669 (CASP3)    05014 Amyotrophic lateral sclerosis     461669 (CASP3)    05016 Huntington disease     461669 (CASP3)    05020 Prion disease     461669 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     461669 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     461669 (CASP3)    05416 Viral myocarditis     461669 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     461669 (CASP3)    04932 Non-alcoholic fatty liver disease     461669 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     461669 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     461669 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ptr01002]     461669 (CASP3) Enzymes [BR:ptr01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      461669 (CASP3) Peptidases and inhibitors [BR:ptr01002]  Cysteine peptidases   Family C14: caspase family    461669 (CASP3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 SICA_beta Motif Other DBs NCBI-GeneID:  461669 NCBI-ProteinID:  XP_016806492 Ensembl:  ENSPTRG00000016640 VGNC:  2081 UniProt:  Q5IS54 A0A663DA81 K7D0A9 LinkDB All DBs Position 3:complement(186269277..186291091) Genome browser AA seq 277 aa AA seqDB search MENTENSVDSKSIKNLEPKIIHGSQSMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacaccgaaaactcagtggattcaaaatccattaaaaatttggaaccaaagatc atacatggaagccaatcgatggactctggaatatccctggacaacagttataaaatggat tatcctgagatgggtttatgtataatcattaataataagaattttcataaaagcactgga atgacatctcggtctggtacagatgtcgatgcagcaaacctcagggaaacattcagaaac ttgaaatatgaagtcaggaataaaaatgatcttacacgtgaagaaattgtggaattgatg cgtgatgtttctaaagaagatcacagcaaaaggagcagttttgtttgtgtgcttctgagc catggtgaagaaggaataatttttggaacaaatggacctgttgacctgaaaaaaataaca aactttttcagaggggatcgttgtagaagtctaactggaaaacccaaacttttcattatt caggcctgccgtggtacagaactggactgtggcattgagacagacagtggtgttgatgat gacatggcgtgtcataaaataccagtggaggccgacttcttgtatgcatactccacagca cctggttattattcttggcgaaattcaaaggatggctcctggttcatccagtcgctttgt gccatgctgaaacagtatgccgacaagcttgaatttatgcacattcttacccgggttaac cgaaaggtggcaacagaatttgagtccttttcctttgacgctacttttcatgcaaagaaa cagattccatgtattgtttccatgctcacaaaagaactctatttttatcactaa

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