Pan troglodytes (chimpanzee): 741876
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Entry
741876 CDS
T01005
Symbol
GPX4
Name
(RefSeq) phospholipid hydroperoxide glutathione peroxidase
KO
K05361
phospholipid-hydroperoxide glutathione peroxidase [EC:
1.11.1.12
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00480
Glutathione metabolism
ptr00590
Arachidonic acid metabolism
ptr01100
Metabolic pathways
ptr04216
Ferroptosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
741876 (GPX4)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
741876 (GPX4)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
741876 (GPX4)
Enzymes [BR:
ptr01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase
741876 (GPX4)
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Gene cluster
GFIT
Motif
Pfam:
GSHPx
AhpC-TSA
Motif
Other DBs
NCBI-GeneID:
741876
NCBI-ProteinID:
NP_001139295
Ensembl:
ENSPTRG00000010184
VGNC:
2549
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Position
19:945311..947475
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AA seq
234 aa
AA seq
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MGRAGARSPGRRRQRCQSRGRRRPRAPRRRKAPACRRRRARRRRKKPCPRSLRPEIHECP
ESQDPCASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQL
VDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPL
WKWMKIQPKGKGILGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF
NT seq
705 nt
NT seq
+upstream
nt +downstream
nt
atgggccgcgcgggcgcacgctcccccgggcgccgcaggcagcggtgccagagccggggc
aggcggcggccgcgagcccctcggcggcggaaggccccagcgtgcaggcgcaggagggcg
cggcgccggcggaagaagccctgtccccgcagcttgcgaccggagatccacgaatgtccc
gagtcccaggacccgtgcgcgtcccgggacgactggcgctgtgcgcgctccatgcacgag
ttttccgccaaggacatcgacgggcacatggttaacctggacaagtaccggggcttcgtg
tgcatcgtcaccaacgtggcctcccagtgaggcaagaccgaagtaaactacactcagctc
gtcgacctgcacgcccgatacgctgagtgtggtttgcggatcctggccttcccgtgtaac
cagttcgggaagcaggagccagggagtaacgaagagatcaaagagttcgccgcgggctac
aacgtcaaattcgatatgttcagcaagatctgcgtgaacggggatgacgcccacccgctg
tggaagtggatgaagatccaacccaagggcaagggcatcctgggaaatgccatcaagtgg
aacttcaccaagttcctcatcgacaagaacggctgcgtggtgaagcgctacggacccatg
gaggagcccctggtgatagagaaggacctgccccactatttctag
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