Rattus norvegicus (rat): 296925
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Entry
296925 CDS
T01003
Symbol
Aass
Name
(RefSeq) alpha-aminoadipic semialdehyde synthase, mitochondrial precursor
KO
K14157
alpha-aminoadipic semialdehyde synthase [EC:
1.5.1.8
1.5.1.9
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00310
Lysine degradation
rno01100
Metabolic pathways
Module
rno_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
296925 (Aass)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming)
296925 (Aass)
1.5.1.9 saccharopine dehydrogenase (NAD+, L-glutamate-forming)
296925 (Aass)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Sacchrp_dh_C
Sacchrp_dh_NADP
AlaDh_PNT_N
AlaDh_PNT_C
DUF2325
Shikimate_DH
Motif
Other DBs
NCBI-GeneID:
296925
NCBI-ProteinID:
NP_001094433
RGD:
1310811
Ensembl:
ENSRNOG00000039494
UniProt:
A2VCW9
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All DBs
Position
4:complement(52572146..52628811)
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AA seq
926 aa
AA seq
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MLRAQRLRLARLRACVSRGLHHKPVMALRREDVNAWERRAPLAPKHIKGITKLGYKVLIQ
PSNRRAIHDKEYVRAGGILQEDITEACLILGVKRPPEEKLMSKKTYAFFSHTIKAQEANM
SLLDEVLKQEIRLIDYEKMVDHRGSRIVAFGHWAGVAGMINILHGMGLRLLALGHHTPFM
HLGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEVFNELPC
EYVEPHELKEVSKTGDLRKVYGTVLSRHHHLVRKTDGVYDPVEYEKYPERYISRFNADIA
PYTTCLINGIYWEQNTPRLLTRQDAQSLLVPVKSSVVPVEGCPELPHKLVAICDISADTG
GSIDFMTECTTIERPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATEYFGDMLY
PYVEEMLLSDASQPLESQNFSPVVRDAVITSNGLLTDKYKYIQKLRESRERIQFLSMSTK
KKVLVLGSGYVSGPVLEYLSRGNNIEITLGSDMTNQMQQLSKKYDINTVNVTVGKQEDKL
QSLVESQDLVISLLPYVLHPVVAKACIDSKVNMVTASYITPAMKELEKSVDDAGITVIGE
LGLDPGLDHMLAMETIDKAKDLGATIESYVSYCGGLPAPEHSDNPLRYKFSWSPVGVLMN
IMQPASYLLNGKVVNVTGGVSFLNSVTPMDYFPGLNLEGYPNRDSTKYAEIYGISSAHTL
LRGTLRYKGYSKALNGFVKLGLINRETYPALRPEANPLTWKQLLCDLVGISRSSSCEKLK
EVVFTKLGGDSTQLEAAEWLGLLGDEQVPQAESIVDAFSKHLVSKLSYGPEEKDMIVMRD
SFGIRHPSGHLENKTIDLVVYGDFNGFSAMAKTVGLPTAMAAKMLLDGEIETKGLMGPFS
KEIYGPILERIKAEGIVFNTQSTIKL
NT seq
2781 nt
NT seq
+upstream
nt +downstream
nt
atgctgagagcacagaggctgagactggccaggctgagagcctgcgtctccagaggcctc
caccacaagccggtcatggcgctccgaagggaggacgtgaacgcctgggagcgcagggcg
cctctggctcccaagcacatcaagggcatcaccaaactgggatacaaggtcttgatacag
ccttccaatagacgagccattcacgacaaggagtatgtcagggccggtggcattcttcag
gaggacattacagaagcctgcctgattttgggggtaaaaaggcctccagaggaaaaactg
atgtccaagaagacttatgccttcttctcccacacaataaaagctcaggaagctaatatg
agcttgctggatgaggtcctgaaacaggaaatccggcttattgattatgagaaaatggtg
gatcacagagggtctcggatagtggcttttggacattgggcaggtgtggcaggaatgatt
aatattttacatggaatgggtttaaggctccttgctttgggacatcatacgcctttcatg
catctcggcatggctcacaactacaggaacagcagtcaagctgtacaggctgtccgcgat
gctggctatgaaatatctctgggtttaatgccaaagtcaatagggcccttaacgtttgta
ttcacagggactggcaacgtatccaagggagcccaagaagtctttaatgagctaccttgt
gagtatgtggagccccatgaattaaaagaagtttcaaaaactggagacctcaggaaagtg
tatgggacggtgttaagtcgccatcatcatcttgtcaggaaaacagatggtgtgtacgat
cctgtagaatacgagaaatatcctgagcgctacataagtcgttttaatgcagatattgca
ccctacacaacttgtttaatcaatggaatctactgggagcaaaacacccctcggctgctc
acacgtcaggatgcccagagtctcctggtcccagtgaagtcctcagttgttcctgttgaa
ggatgtcctgaattaccacacaaacttgtggcaatatgtgacatttcagcagacacagga
ggctctatagattttatgactgagtgcactaccatagaacggcccttttgcatgtatgac
gcagaccagcatattattcacgacagtgttgaaggctccgggattctgatgtgctccatt
gacaatttgccagcgcagcttccaattgaggccacagaatactttggagacatgctttac
ccttatgtcgaagagatgctgttatcagatgcgtcacagcctctggaaagccagaacttc
tctccggtcgtgcgagatgcagtgattacatccaatggtctattgacggacaaatacaaa
tatatacagaaactccgggaaagcagagaacgaatccaattcctttcaatgagtaccaag
aagaaggttttggttcttgggtctggctatgtatctgggcctgttttggagtacctgtca
agaggcaacaatatagaaataacactaggctctgacatgacgaaccaaatgcagcagctg
agcaagaaatacgacattaacactgtcaatgtgaccgtcggcaagcaggaagacaagctg
cagtccctggtcgaatcccaggatcttgtcatcagcttgttgccttatgtgttgcatcct
gttgtggccaaggcctgcattgatagcaaggttaatatggtcactgcaagctacatcaca
ccagctatgaaagaactggaaaaaagtgtggatgacgctggcatcacagtcattggagaa
ttgggattagatcctggtcttgatcacatgttggcaatggaaacaattgataaagccaaa
gatctgggagccacgattgagtcgtatgtttcctactgcggtggtcttccagccccagag
cattcagataatcccttgcgatataagttcagctggagtccagtgggagtcttgatgaac
ataatgcagcctgctagctatctcctcaacggaaaggttgtgaatgtgacagggggagtc
tcttttctcaattctgtcacacccatggattacttcccaggcctaaacttggaagggtat
cctaacagagatagcacaaaatatgctgagatttatggaatttcatctgcccatacattg
ttgaggggaacactgagatataagggatattccaaagctttgaacggatttgtgaagttg
ggactcatcaacagagaaacatatcctgccctccgacctgaggccaaccctctcacgtgg
aaacagctcctgtgtgacctagttgggatttcccgctcctcctcatgtgagaagcttaag
gaagttgtctttacaaagttgggaggggacagtacccagctagaggctgctgaatggttg
ggcttactgggggatgagcaggttcctcaggcagagtccattgtggatgcattctccaag
cacttggtctcaaagctctcctatggccccgaagaaaaggatatgattgtgatgcgggac
agctttggcattagacatccatctggacatttagaaaacaagaccattgatcttgtggtt
tatggagacttcaatggcttttcggcaatggctaagactgtggggttgccaacagccatg
gcagccaaaatgttactcgatggtgaaattgaaaccaaaggcctaatgggaccattttca
aaggagatctacgggccaatattggagcggattaaagcagaaggcattgtgtttaataca
cagagcacaatcaagctataa
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